Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A - Naganawa, Mika; Gallezot, Jean-Dominique; Finnema, Sjoerd J.; Maguire, Ralph Paul; Mercier, Joël; Nabulsi, Nabeel B.; Kervyn, Sophie; Henry, Shannan; Nicolas, Jean-Marie; Huang, Yiyun; Chen, Ming-Kai; Hannestad, Jonas; et al. (EJNMMI research, 2022)
Keywords: Brain; Cardiac Imaging; Displacement; Drug dosages; Drugs; Emission analysis; Glycoproteins; Imaging; Kinetic modeling; Lower bounds; Mathematical models; Medicine; Medicine & Public Health; Nonlinear differential equations; Nuclear Medicine; Occupancy; Oncology; Original Research; Orthopedics; Parameters; Positron emission; Positron emission tomography; Radiology; SV2A; Kinetic modeling; SV2A; Positron emission tomography; Displacement; Occupancy