Reproductive biology and IVF: ovarian stimulation and luteal phase consequences

Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called ‘controlled’ ovarian hyperstimulation, using maximum stimulation by exogenous gonadotropins, together with the gonadotropin-releasing hormone (GnRH) agoni...

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Published inTrends in endocrinology and metabolism Vol. 14; no. 5; pp. 236 - 242
Main Authors Fauser, Bart C.J.M., Devroey, Paul
Format Journal Article
LanguageEnglish
Published London Elsevier Ltd 01.07.2003
Elsevier
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Online AccessGet full text
ISSN1043-2760
1879-3061
DOI10.1016/S1043-2760(03)00075-4

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Abstract Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called ‘controlled’ ovarian hyperstimulation, using maximum stimulation by exogenous gonadotropins, together with the gonadotropin-releasing hormone (GnRH) agonist long-protocol. Potential detrimental effects of this approach with regard to oocyte quality, corpus luteum function and endometrial receptivity have been largely ignored. These factors might by themselves have a major impact on IVF outcome and should therefore be considered seriously. The recent introduction of GnRH antagonists along with the current emphasis on the need for transfer of a reduced number of embryos enables a careful re-evaluation of current IVF strategies. We can now render stimulation protocols simpler, starting with a spontaneous menstrual cycle, allowing for more subtle interference with single dominant follicle selection. Here, we discuss recent approaches to ovarian stimulation, the induction of oocyte maturation, and effects of these altered follicular phase interventions on corpus luteum function following ovarian stimulation.
AbstractList Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called 'controlled' ovarian hyperstimulation, using maximum stimulation by exogenous gonadotropins, together with the gonadotropin-releasing hormone (GnRH) agonist long-protocol. Potential detrimental effects of this approach with regard to oocyte quality, corpus luteum function and endometrial receptivity have been largely ignored. These factors might by themselves have a major impact on IVF outcome and should therefore be considered seriously. The recent introduction of GnRH antagonists along with the current emphasis on the need for transfer of a reduced number of embryos enables a careful re-evaluation of current IVF strategies. We can now render stimulation protocols simpler, starting with a spontaneous menstrual cycle, allowing for more subtle interference with single dominant follicle selection. Here, we discuss recent approaches to ovarian stimulation, the induction of oocyte maturation, and effects of these altered follicular phase interventions on corpus luteum function following ovarian stimulation.
Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called ‘controlled’ ovarian hyperstimulation, using maximum stimulation by exogenous gonadotropins, together with the gonadotropin-releasing hormone (GnRH) agonist long-protocol. Potential detrimental effects of this approach with regard to oocyte quality, corpus luteum function and endometrial receptivity have been largely ignored. These factors might by themselves have a major impact on IVF outcome and should therefore be considered seriously. The recent introduction of GnRH antagonists along with the current emphasis on the need for transfer of a reduced number of embryos enables a careful re-evaluation of current IVF strategies. We can now render stimulation protocols simpler, starting with a spontaneous menstrual cycle, allowing for more subtle interference with single dominant follicle selection. Here, we discuss recent approaches to ovarian stimulation, the induction of oocyte maturation, and effects of these altered follicular phase interventions on corpus luteum function following ovarian stimulation.
Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called 'controlled' ovarian hyperstimulation, using maximum stimulation by exogenous gonadotropins, together with the gonadotropin-releasing hormone (GnRH) agonist long-protocol. Potential detrimental effects of this approach with regard to oocyte quality, corpus luteum function and endometrial receptivity have been largely ignored. These factors might by themselves have a major impact on IVF outcome and should therefore be considered seriously. The recent introduction of GnRH antagonists along with the current emphasis on the need for transfer of a reduced number of embryos enables a careful re-evaluation of current IVF strategies. We can now render stimulation protocols simpler, starting with a spontaneous menstrual cycle, allowing for more subtle interference with single dominant follicle selection. Here, we discuss recent approaches to ovarian stimulation, the induction of oocyte maturation, and effects of these altered follicular phase interventions on corpus luteum function following ovarian stimulation.Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called 'controlled' ovarian hyperstimulation, using maximum stimulation by exogenous gonadotropins, together with the gonadotropin-releasing hormone (GnRH) agonist long-protocol. Potential detrimental effects of this approach with regard to oocyte quality, corpus luteum function and endometrial receptivity have been largely ignored. These factors might by themselves have a major impact on IVF outcome and should therefore be considered seriously. The recent introduction of GnRH antagonists along with the current emphasis on the need for transfer of a reduced number of embryos enables a careful re-evaluation of current IVF strategies. We can now render stimulation protocols simpler, starting with a spontaneous menstrual cycle, allowing for more subtle interference with single dominant follicle selection. Here, we discuss recent approaches to ovarian stimulation, the induction of oocyte maturation, and effects of these altered follicular phase interventions on corpus luteum function following ovarian stimulation.
Author Fauser, Bart C.J.M.
Devroey, Paul
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  givenname: Paul
  surname: Devroey
  fullname: Devroey, Paul
  organization: Center for Reproductive Medicine, University Hospital, Dutch-speaking Free University of Brussels (Vrije Universiteit), Brussels, Belgium
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Issue 5
Keywords In vitro fertilization embryo transfer
Assisted procreation
Ovary
Stimulation
Luteal phase
Female genital system
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References Contemporary pharmacological manipulation in assisted reproduction.
Elter, Nelson (BIB33) 2001; 56
Fluker (BIB36) 2001; 75
Collins (BIB65) 2002; 8
Fauser (BIB2) 2002; 8
Strandell (BIB58) 2000; 15
Edwards (BIB55) 1996; 11
Toner (BIB60) 2002; 78
Ragni (BIB53) 2001; 16
Hernandez (BIB37) 2000; 15
Kligman, Rosenwaks (BIB64) 2001; 76
Gonen (BIB41) 1990; 71
Beckers (BIB6) 2002; 78
Wortham (BIB9) 1983; 40
Huirne, J.A.
Fauser (BIB4) 1999; 14
Wikland (BIB25) 2001; 16
fertilization.
Pantos (BIB51) 1994; 61
Delvigne, Rozenberg (BIB22) 2002; 8
Janssens (BIB30) 2000; 15
Jennings (BIB1) 1996; 52
Trounson (BIB8) 1981; 212
Hugues, Cedrin (BIB31) 1998; 4
Borm, Mannaerts (BIB35) 2000; 15
Dickey (BIB14) 2002; 77
Al Inany, Aboulghar (BIB23) 2002; 17
Gerris (BIB56) 1999; 14
Hillier (BIB66) 1985; 12
Macklon, Fauser (BIB61) 2000; 6
Filicori (BIB20) 2002; 17
(in press).
Beckers, N.G.
Jones (BIB48) 1996; 11
Albano (BIB34) 2000; 15
Bancsi (BIB5) 2002; 77
Westergaard (BIB18) 2000; 15
Oehninger, Hodgen (BIB67) 1990; 4
Sykes (BIB13) 2001; 16
Casper, Yen (BIB45) 1979; 205
Mais (BIB46) 1986; 62
Edwards (BIB7) 1980; 87
(BIB16) 2001; 86
Hohmann (BIB29) 2003; 88
Shoham (BIB40) 1995; 64
Out (BIB11) 1995; 10
Bouchard, Fauser (BIB32) 2000; 73
Pelinck (BIB62) 2002; 8
79, 621–623.
Fleming (BIB19) 2000; 15
Simon (BIB43) 1998; 70
Beckers (BIB54) 2002
Macklon (BIB63) 2002; 8
Martikainen (BIB57) 2001; 16
de Jong (BIB38) 2001; 75
Smitz (BIB49) 1992; 7
Duffy (BIB44) 1999; 84
(2003) First live birth after ovarian stimulation using a chimeric long-acting human recombinant follicle-stimulating hormone (FSH) agonist (recFSH–CTP) for
Whelan, Vlahos (BIB21) 2000; 73
van Heusden, Fauser (BIB27) 2002; 8
Nygren, Andersen (BIB59) 2001; 16
(BIB15) 2002; 78
Frydman (BIB52) 1991; 56
Hohmann (BIB28) 2001; 16
Fauser (BIB42) 2002; 87
Daya (BIB12) 2002; 77
Fauser, van Heusden (BIB26) 1997; 18
Filicori (BIB39) 2001; 86
Weissman (BIB47) 1996; 11
Fauser (BIB10) 1998; 13
Out (BIB24) 2001; 16
Pritts, Atwood (BIB50) 2002; 17
References_xml – volume: 16
  start-page: 2459
  year: 2001
  end-page: 2471
  ident: BIB59
  article-title: Assisted reproductive technology in Europe, 1998. Results generated from European registers by ESHRE. European society of human reproduction and embryology
  publication-title: Hum. Reprod.
– volume: 15
  start-page: 2333
  year: 2000
  end-page: 2340
  ident: BIB30
  article-title: Dose-finding study of triptorelin acetate for prevention of a premature LH surge in IVF: a prospective, randomized, double-blind, placebo-controlled study
  publication-title: Hum. Reprod.
– volume: 17
  start-page: 874
  year: 2002
  end-page: 885
  ident: BIB23
  article-title: GnRH antagonist in assisted reproduction: a Cochrane review
  publication-title: Hum. Reprod.
– reference: (in press).
– volume: 16
  start-page: 2557
  year: 2001
  end-page: 2562
  ident: BIB13
  article-title: The cost-effectiveness of IVF in the UK: a comparison of three gonadotrophin treatments
  publication-title: Hum. Reprod.
– volume: 8
  start-page: 1
  year: 2002
  end-page: 9
  ident: BIB2
  article-title: Alternative approaches in IVF
  publication-title: Hum. Reprod. Update
– volume: 15
  start-page: 1440
  year: 2000
  end-page: 1445
  ident: BIB19
  article-title: Suppression of LH during ovarian stimulation: effects differ in cycles stimulated with purified urinary FSH and recombinant FSH
  publication-title: Hum. Reprod.
– reference: fertilization.
– volume: 14
  start-page: 2581
  year: 1999
  end-page: 2587
  ident: BIB56
  article-title: Prevention of twin pregnancy after
  publication-title: Hum. Reprod.
– volume: 14
  start-page: 2681
  year: 1999
  end-page: 2686
  ident: BIB4
  article-title: Minimal ovarian stimulation for IVF: appraisal of potential benefits and drawbacks
  publication-title: Hum. Reprod.
– volume: 8
  start-page: 265
  year: 2002
  end-page: 277
  ident: BIB65
  article-title: An international survey of the health economics of IVF and ICSI
  publication-title: Hum. Reprod. Update
– volume: 56
  start-page: 576
  year: 2001
  end-page: 588
  ident: BIB33
  article-title: Use of third generation gonadotropin-releasing hormone antagonists in
  publication-title: Obstet. Gynecol. Surv.
– volume: 17
  start-page: 517
  year: 2002
  end-page: 520
  ident: BIB20
  article-title: The potential value of mid-follicular phase LH
  publication-title: Hum. Reprod.
– reference: 79, 621–623.
– volume: 76
  start-page: 1185
  year: 2001
  end-page: 1190
  ident: BIB64
  article-title: Differentiating clinical profiles: predicting good responders, poor responders, and hyperresponders
  publication-title: Fertil. Steril.
– volume: 15
  start-page: 1490
  year: 2000
  end-page: 1498
  ident: BIB35
  article-title: Treatment with the GnRH antagonist ganirelix in women undergoing ovarian stimulation with recombinant FSH is effective, safe and convenient: results of a controlled, randomized, multi center trial
  publication-title: Hum. Reprod.
– reference: Contemporary pharmacological manipulation in assisted reproduction.
– volume: 11
  start-page: 943
  year: 1996
  end-page: 949
  ident: BIB47
  article-title: Recovery of corpus luteum function after prolonged deprivation from gonadotrophin stimulation
  publication-title: Hum. Reprod.
– volume: 77
  start-page: 328
  year: 2002
  end-page: 336
  ident: BIB5
  article-title: Predictors of poor ovarian response in
  publication-title: Fertil. Steril.
– volume: 40
  start-page: 170
  year: 1983
  end-page: 177
  ident: BIB9
  article-title: Vital initiation of pregnancy using human menopausal gonadotropin and human chorionic gonadotropin ovulation induction: phase II–1981
  publication-title: Fertil. Steril.
– volume: 86
  start-page: 337
  year: 2001
  end-page: 343
  ident: BIB39
  article-title: Luteinizing hormone activity in menotropins optimizes folliculogenesis and treatment in controlled ovarian stimulation
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 6
  start-page: 307
  year: 2000
  end-page: 312
  ident: BIB61
  article-title: Regulation of follicle development and novel approaches to ovarian stimulation for IVF
  publication-title: Hum. Reprod. Update
– volume: 70
  start-page: 234
  year: 1998
  end-page: 239
  ident: BIB43
  article-title: Increasing uterine receptivity by decreasing estradiol levels during the preimplantation period in high responders with the use of a follicle-stimulating hormone step-down regimen
  publication-title: Fertil. Steril.
– volume: 84
  start-page: 342
  year: 1999
  end-page: 349
  ident: BIB44
  article-title: Titrating luteinizing hormone replacement to sustain the structure and function of the corpus luteum after gonadotropin-releasing hormone antagonist treatment in rhesus monkeys
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 10
  start-page: 2534
  year: 1995
  end-page: 2540
  ident: BIB11
  article-title: A prospective, randomized, assessor-blind, multicentre study comparing recombinant and urinary follicle stimulating hormone (Puregon versus Metrodin) in
  publication-title: Hum. Reprod.
– volume: 62
  start-page: 1250
  year: 1986
  end-page: 1255
  ident: BIB46
  article-title: The dependency of folliculogenesis and corpus luteum function on pulsatile gonadotropin secretion in cycling women using a gonadotropin-releasing hormone antagonist as a probe
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 75
  start-page: 38
  year: 2001
  end-page: 45
  ident: BIB36
  article-title: Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation
  publication-title: Hum. Reprod.
– volume: 71
  start-page: 918
  year: 1990
  end-page: 922
  ident: BIB41
  article-title: Use of gonadotropin-releasing hormone agonist to trigger follicular maturation for
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 205
  start-page: 408
  year: 1979
  end-page: 410
  ident: BIB45
  article-title: Induction of luteolysis in the human with a long-acting analog of luteinizing hormone-releasing factor
  publication-title: Science
– volume: 87
  start-page: 709
  year: 2002
  end-page: 715
  ident: BIB42
  article-title: Endocrine profiles after triggering of final oocyte maturation with GnRH agonist after cotreatment with the GnRH antagonist ganirelix during ovarian hyperstimulation for
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 61
  start-page: 709
  year: 1994
  end-page: 713
  ident: BIB51
  article-title: Prospective study of a modified gonadotropin-releasing hormone agonist long protocol in an
  publication-title: Fertil. Steril.
– volume: 18
  start-page: 71
  year: 1997
  end-page: 106
  ident: BIB26
  article-title: Manipulation of human ovarian function: physiological concepts and clinical consequences
  publication-title: Endocr. Rev.
– volume: 4
  start-page: 83
  year: 1998
  end-page: 101
  ident: BIB31
  article-title: Revisiting gonadotrophin-releasing hormone agonist protocols and management of poor ovarian responses to gonadotrophins
  publication-title: Hum. Reprod. Update
– volume: 11
  start-page: 917
  year: 1996
  end-page: 919
  ident: BIB55
  article-title: Time to revolutionize ovarian stimulation
  publication-title: Hum. Reprod.
– volume: 64
  start-page: 237
  year: 1995
  end-page: 251
  ident: BIB40
  article-title: The luteinizing hormone surge – the final stage in ovulation induction: modern aspects of ovulation triggering
  publication-title: Fertil. Steril.
– volume: 77
  start-page: 711
  year: 2002
  end-page: 714
  ident: BIB12
  article-title: Updated meta-analysis of recombinant follicle-stimulating hormone (FSH) versus urinary FSH for ovarian stimulation in assisted reproduction
  publication-title: Fertil. Steril.
– volume: 86
  start-page: 2607
  year: 2001
  end-page: 2618
  ident: BIB16
  article-title: Human recombinant luteinizing hormone is as effective as, but safer than, urinary human chorionic gonadotropin in inducing final follicular maturation and ovulation in
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 15
  start-page: 2520
  year: 2000
  end-page: 2525
  ident: BIB58
  article-title: Selection of patients suitable for one-embryo transfer may reduce the rate of multiple births by half without impairment of overall birth rates
  publication-title: Hum. Reprod.
– volume: 78
  start-page: 291
  year: 2002
  end-page: 297
  ident: BIB6
  article-title: Women with regular menstrual cycles and a poor response to ovarian hyperstimulation for
  publication-title: Fertil. Steril.
– volume: 4
  start-page: 541
  year: 1990
  end-page: 573
  ident: BIB67
  article-title: Induction of ovulation for assisted reproduction programmes
  publication-title: Baillieres Clin. Obstet. Gynaecol.
– volume: 12
  start-page: 687
  year: 1985
  end-page: 723
  ident: BIB66
  article-title: Superovulation strategy before
  publication-title: Clin. Obstet. Gynaecol.
– volume: 15
  start-page: 1211
  year: 2000
  end-page: 1216
  ident: BIB37
  article-title: Embryo implantation and GnRH antagonists: embryo implantation: the Rubicon for GnRH antagonists
  publication-title: Hum. Reprod.
– reference: (2003) First live birth after ovarian stimulation using a chimeric long-acting human recombinant follicle-stimulating hormone (FSH) agonist (recFSH–CTP) for
– volume: 16
  start-page: 2258
  year: 2001
  end-page: 2262
  ident: BIB53
  article-title: Comparison of luteal phase profile in gonadotrophin stimulated cycles with or without a gonadotrophin-releasing hormone antagonist
  publication-title: Hum. Reprod.
– reference: Huirne, J.A.
– volume: 11
  start-page: 7
  year: 1996
  end-page: 24
  ident: BIB48
  article-title: What has happened? Where are we?
  publication-title: Hum. Reprod.
– volume: 7
  start-page: 1098
  year: 1992
  end-page: 1102
  ident: BIB49
  article-title: The effect of gonadotrophin-releasing hormone (GnRH) agonist in the follicular phase on
  publication-title: Hum. Reprod.
– volume: 56
  start-page: 923
  year: 1991
  end-page: 927
  ident: BIB52
  article-title: Prevention of premature luteinizing hormone and progesterone rise with a gonadotropin-releasing hormone antagonist, Nal-Glu, in controlled ovarian hyperstimulation
  publication-title: Fertil. Steril.
– volume: 212
  start-page: 681
  year: 1981
  end-page: 682
  ident: BIB8
  article-title: Pregnancies in humans by fertilization
  publication-title: Science
– volume: 75
  start-page: 688
  year: 2001
  end-page: 693
  ident: BIB38
  article-title: Dynamics of the development of multiple follicles during ovarian stimulation for
  publication-title: Fertil. Steril.
– volume: 17
  start-page: 2287
  year: 2002
  end-page: 2299
  ident: BIB50
  article-title: Luteal phase support in infertility treatment: a meta-analysis of the randomized trials
  publication-title: Hum. Reprod.
– reference: Beckers, N.G.
– volume: 77
  start-page: 1202
  year: 2002
  end-page: 1208
  ident: BIB14
  article-title: Comparison of the efficacy and safety of a highly purified human follicle-stimulating hormone (Bravelle) and recombinant follitropin-β for
  publication-title: Fertil. Steril.
– volume: 8
  start-page: 345
  year: 2002
  end-page: 358
  ident: BIB27
  article-title: Residual ovarian activity during oral steroid contraception
  publication-title: Hum. Reprod. Update
– volume: 16
  start-page: 1900
  year: 2001
  end-page: 1903
  ident: BIB57
  article-title: One versus two embryo transfer after IVF and ICSI: a randomized study
  publication-title: Hum. Reprod.
– volume: 8
  start-page: 129
  year: 2002
  end-page: 139
  ident: BIB62
  article-title: Efficacy of natural cycle IVF: a review of the literature
  publication-title: Hum. Reprod. Update
– volume: 78
  start-page: 520
  year: 2002
  end-page: 528
  ident: BIB15
  article-title: Efficacy and safety of highly purified menotropin versus recombinant follicle-stimulating hormone in
  publication-title: Fertil. Steril.
– volume: 87
  start-page: 737
  year: 1980
  end-page: 756
  ident: BIB7
  article-title: Establishing full-term human pregnancies using cleaving embryos grown
  publication-title: Br. J. Obstet. Gynaecol.
– volume: 16
  start-page: 1676
  year: 2001
  end-page: 1681
  ident: BIB25
  article-title: A prospective, randomized comparison of two starting doses of recombinant FSH in combination with cetrorelix in women undergoing ovarian stimulation for IVF/ICSI
  publication-title: Hum. Reprod.
– volume: 15
  start-page: 526
  year: 2000
  end-page: 531
  ident: BIB34
  article-title: Ovarian stimulation with HMG: results of a prospective randomized phase III European study comparing the luteinizing hormone-releasing hormone (LHRH)-antagonist cetrorelix and the LHRH-agonist buserelin
  publication-title: Hum. Reprod.
– start-page: O
  year: 2002
  end-page: 157
  ident: BIB54
  article-title: Comparison of the non-supplemented luteal phase characteristics after recombinant (r)HCG, rLH or GnRH agonist for oocyte maturation in IVF
  publication-title: Hum. Reprod. (Abstr.)
– volume: 52
  start-page: 313
  year: 1996
  end-page: 343
  ident: BIB1
  publication-title: Drugs
– volume: 15
  start-page: 1003
  year: 2000
  end-page: 1008
  ident: BIB18
  article-title: Increased risk of early pregnancy loss by profound suppression of luteinizing hormone during ovarian stimulation in normogonadotrophic women undergoing assisted reproduction
  publication-title: Hum. Reprod.
– volume: 16
  start-page: 846
  year: 2001
  end-page: 854
  ident: BIB28
  article-title: Low-dose exogenous FSH initiated during the early, mid or late follicular phase can induce multiple dominant follicle development
  publication-title: Hum. Reprod.
– volume: 16
  start-page: 1104
  year: 2001
  end-page: 1109
  ident: BIB24
  article-title: A randomized, double-blind clinical trial using fixed daily doses of 100 or 200 IU of recombinant FSH in ICSI cycles
  publication-title: Hum. Reprod.
– volume: 78
  start-page: 943
  year: 2002
  end-page: 950
  ident: BIB60
  article-title: Progress we can be proud of: US trends in assisted reproduction over the first 20 years
  publication-title: Fertil. Steril.
– volume: 88
  start-page: 166
  year: 2003
  end-page: 173
  ident: BIB29
  article-title: A randomized comparison of two ovarian stimulation protocols with GnRH antagonist cotreatment for IVF commencing recombinant FSH on cycle day 2 or 5 with the standard long GnRH agonist protocol
  publication-title: J. Clin. Endocrinol. Metab.
– volume: 73
  start-page: 883
  year: 2000
  end-page: 896
  ident: BIB21
  article-title: The ovarian hyperstimulation syndrome
  publication-title: Fertil. Steril.
– volume: 73
  start-page: 18
  year: 2000
  end-page: 20
  ident: BIB32
  article-title: Gonadotropin-releasing hormone antagonist: new tools vs. old habits
  publication-title: Fertil. Steril.
– volume: 8
  start-page: 333
  year: 2002
  end-page: 343
  ident: BIB63
  article-title: Conception to ongoing pregnancy: the ‘black box’ of early pregnancy loss
  publication-title: Hum. Reprod. Update
– volume: 13
  start-page: 36
  year: 1998
  end-page: 46
  ident: BIB10
  article-title: Developments in human recombinant follicle stimulating hormone technology: are we going in the right direction?
  publication-title: Hum. Reprod.
– volume: 8
  start-page: 291
  year: 2002
  end-page: 296
  ident: BIB22
  article-title: A qualitative systematic review of coasting, a procedure to avoid ovarian hyperstimulation syndrome in IVF patients
  publication-title: Hum. Reprod. Update
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Snippet Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called ‘controlled’...
Most clinicians working in in vitro fertilization (IVF) centers worldwide have taken for granted for more than a decade the paradigm of so-called 'controlled'...
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SubjectTerms Adult
Animals
Biological and medical sciences
Birth control
Female
Fertilization in Vitro
Fundamental and applied biological sciences. Psychology
Gonadotropins - pharmacology
Gynecology. Andrology. Obstetrics
Hormone metabolism and regulation
Humans
Luteal Phase - physiology
Mammalian female genital system
Medical sciences
Ovulation Induction
Pregnancy
Reproduction - physiology
Sterility. Assisted procreation
Vertebrates: reproduction
Title Reproductive biology and IVF: ovarian stimulation and luteal phase consequences
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