C-reactive protein, procalcitonin, interleukin-6, vascular endothelial growth factor and oxidative metabolites in diagnosis of infection and staging in patients with gastric cancer
The current study was to determine the serum/plasmalevels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide(NO), PCT and CRP in gastric carcinoma and correlation withthe stages of the disease and accompanying infection.
Saved in:
| Published in | World journal of gastroenterology : WJG Vol. 10; no. 8; pp. 1115 - 1120 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Department of Biochemistry and Clinical Biochemistry, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Department of General Surgery, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Division of Immunology, Firat University Firat Medical Centre, 23119, Elazig, Turkey
15.04.2004
Baishideng Publishing Group Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1007-9327 2219-2840 |
| DOI | 10.3748/wjg.v10.i8.1115 |
Cover
| Abstract | The current study was to determine the serum/plasmalevels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide(NO), PCT and CRP in gastric carcinoma and correlation withthe stages of the disease and accompanying infection. |
|---|---|
| AbstractList | The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and correlation with the stages of the disease and accompanying infection.AIMThe current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and correlation with the stages of the disease and accompanying infection.We examined the levels of serum VEGF, IL-6, PCT, CRP and plasma MDA, NO in 42 preoperative gastric cancer patients and 23 healthy subjects. There were infection anamneses that had no definite origin in 19 cancer patients.METHODSWe examined the levels of serum VEGF, IL-6, PCT, CRP and plasma MDA, NO in 42 preoperative gastric cancer patients and 23 healthy subjects. There were infection anamneses that had no definite origin in 19 cancer patients.The VEGF levels (mean+/-SD; pg/mL) were 478.05+/-178.29 and 473.85+/-131.24 in gastric cancer patients with and without infection, respectively, and these values were not significantly different (P>0.05). The levels of VEGF, CRP, PCT, IL-6, MDA and NO in cancer patients were significantly higher than those in healthy controls and the levels of CRP, PCT, IL-6, MDA and NO were statistically increased in infection group when compared with non-infection group (P<0.001).RESULTSThe VEGF levels (mean+/-SD; pg/mL) were 478.05+/-178.29 and 473.85+/-131.24 in gastric cancer patients with and without infection, respectively, and these values were not significantly different (P>0.05). The levels of VEGF, CRP, PCT, IL-6, MDA and NO in cancer patients were significantly higher than those in healthy controls and the levels of CRP, PCT, IL-6, MDA and NO were statistically increased in infection group when compared with non-infection group (P<0.001).Although serum VEGF concentrations were increased in gastric cancer, this increase might not be related to infection. CRP, PCT, IL-6, MDA and NO have obvious drawbacks in the diagnosis of infections in cancer patients. These markers may not help to identify infections in the primary evaluation of cancer patients and hence to avoid unnecessary antibiotic treatments as well as hospitalization. According to the results of this study, IL-6, MDA, NO and especially VEGF can be used as useful parameters to diagnose and grade gastric cancer.CONCLUSIONAlthough serum VEGF concentrations were increased in gastric cancer, this increase might not be related to infection. CRP, PCT, IL-6, MDA and NO have obvious drawbacks in the diagnosis of infections in cancer patients. These markers may not help to identify infections in the primary evaluation of cancer patients and hence to avoid unnecessary antibiotic treatments as well as hospitalization. According to the results of this study, IL-6, MDA, NO and especially VEGF can be used as useful parameters to diagnose and grade gastric cancer. The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and correlation with the stages of the disease and accompanying infection. We examined the levels of serum VEGF, IL-6, PCT, CRP and plasma MDA, NO in 42 preoperative gastric cancer patients and 23 healthy subjects. There were infection anamneses that had no definite origin in 19 cancer patients. The VEGF levels (mean+/-SD; pg/mL) were 478.05+/-178.29 and 473.85+/-131.24 in gastric cancer patients with and without infection, respectively, and these values were not significantly different (P>0.05). The levels of VEGF, CRP, PCT, IL-6, MDA and NO in cancer patients were significantly higher than those in healthy controls and the levels of CRP, PCT, IL-6, MDA and NO were statistically increased in infection group when compared with non-infection group (P<0.001). Although serum VEGF concentrations were increased in gastric cancer, this increase might not be related to infection. CRP, PCT, IL-6, MDA and NO have obvious drawbacks in the diagnosis of infections in cancer patients. These markers may not help to identify infections in the primary evaluation of cancer patients and hence to avoid unnecessary antibiotic treatments as well as hospitalization. According to the results of this study, IL-6, MDA, NO and especially VEGF can be used as useful parameters to diagnose and grade gastric cancer. R5; AIM: The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and correlation with the stages of the disease and accompanying infection.METHODS: We examined the levels of serum VEGF, IL-6,PCT, CRP and plasma MDA, NO in 42 preoperative gastric cancer patients and 23 healthy subjects. There were infection anamneses that had no definite origin in 19 cancer patients.RESULTS: The VEGF levels (mean±SD; pg/mL) were 478.05±178.29 and 473.85±131.24 in gastric cancer patients with and without infection, respectively, and these values were not significantly different (P＞0.05). The levels of VEGF,CRP, PCT, IL-6, MDA and NO in cancer patients were significantly higher than those in healthy controls and the levels of CRP, PCT, IL-6, MDA and NO were statistically increased in infection group when compared with noninfection group (P＜0.001).CONCLUSION: Although serum VEGF concentrations were increased in gastric cancer, this increase might not be related to infection. CRP, PCT, IL-6, MDA and NO have obvious drawbacks in the diagnosis of infections in cancer patients.These markers may not help to identify infections in the primary evaluation of cancer patients and hence to avoid unnecessary antibiotic treatments as well as hospitalization.According to the results of this study, IL-6, MDA, NO and especially VEGF can be used as useful parameters to diagnose and grade gastric cancer. The current study was to determine the serum/plasmalevels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide(NO), PCT and CRP in gastric carcinoma and correlation withthe stages of the disease and accompanying infection. AIM: The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and correlation with the stages of the disease and accompanying infection. METHODS: We examined the levels of serum VEGF, IL-6, PCT, CRP and plasma MDA, NO in 42 preoperative gastric cancer patients and 23 healthy subjects. There were infection anamneses that had no definite origin in 19 cancer patients. RESULTS: The VEGF levels (mean ± SD; pg/mL) were 478.05 ± 178.29 and 473.85 ± 131.24 in gastric cancer patients with and without infection, respectively, and these values were not significantly different (P>0.05). The levels of VEGF, CRP, PCT, IL-6, MDA and NO in cancer patients were significantly higher than those in healthy controls and the levels of CRP, PCT, IL-6, MDA and NO were statistically increased in infection group when compared with non-infection group (P<0.001). CONCLUSION: Although serum VEGF concentrations were increased in gastric cancer, this increase might not be related to infection. CRP, PCT, IL-6, MDA and NO have obvious drawbacks in the diagnosis of infections in cancer patients. These markers may not help to identify infections in the primary evaluation of cancer patients and hence to avoid unnecessary antibiotic treatments as well as hospitalization. According to the results of this study, IL-6, MDA, NO and especially VEGF can be used as useful parameters to diagnose and grade gastric cancer. |
| Author | NevinIlhan NecipIlhan YavuzIlhan HandanAkbulut MehmetKǖiǖksu |
| AuthorAffiliation | DepartmentofGeneralSurgery,FiratUniversityFiratMedicalCentre,23119,Elazig,Turkey DepartmentofBiochemistryandClinicalBiochemistry,FiratUniversityFiratMedicalCentre,23119,Elazig,Turkey DivisionofImmunology,FiratUniversityFiratMedicalCentre,23119,Elazig,Turkey |
| AuthorAffiliation_xml | – name: Department of Biochemistry and Clinical Biochemistry, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Department of General Surgery, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Division of Immunology, Firat University Firat Medical Centre, 23119, Elazig, Turkey |
| Author_xml | – sequence: 1 givenname: Nevin surname: Ilhan fullname: Ilhan, Nevin – sequence: 2 givenname: Necip surname: Ilhan fullname: Ilhan, Necip – sequence: 3 givenname: Yavuz surname: Ilhan fullname: Ilhan, Yavuz – sequence: 4 givenname: Handan surname: Akbulut fullname: Akbulut, Handan – sequence: 5 givenname: Mehmet surname: Küçüksu fullname: Küçüksu, Mehmet |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/15069709$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1Uk1vEzEUXKEimhbO3NAiIU7d1PZ-eS-VUMSXVIkLnK233ueNU8dObW8C_4sfiLcJFSBxsf3kmXljz7vIzqyzmGUvKVmWbcWvD5txuU-F5ktKaf0kWzBGu4LxipxlC0pIW3Qla8-zixA2hLCyrNmz7JzWpOla0i2yn6vCI8io95jvvIuo7dV8kGCkjs7OpbYRvcHpTtuiucr3EORkwOdoBxfXaDSYfPTuENe5SlLO52CH3H3XAzzobjFC74yOGJJWPmgYrQs65E6lWmHq7uwDJ0QYtR1n1C5x0caQH3TSHSFEr2UuwUr0z7OnCkzAF6f9Mvv24f3X1afi9svHz6t3t4WsqioWHMqhh1IRhgOrOiAl69Or5dBKShreNl1DUaW164ATVQLwVikGKHs51A0pL7Obo-5u6rc4yOTHgxE7r7fgfwgHWvx9Y_VajG4vqqZuyqpKAm-OAgewCuwoNm7yNlkWKThGSEU4ITzB3p76eHc_YYhiq4NEY8Cim4JoKaesrlgCvvrT0KOT33kmQH0ESO9C8KhEShHm_03-tBGUiHlu5vYizY3QXMxzk3jX__Aepf_LeH1irJ0d71Nqogd5p7RB0bVp8igvfwFz4Ne1 |
| CitedBy_id | crossref_primary_10_1021_acs_bioconjchem_1c00146 crossref_primary_10_1002_cam4_3514 crossref_primary_10_1016_j_jacc_2014_07_948 crossref_primary_10_1016_j_nano_2009_04_004 crossref_primary_10_3233_CBM_210251 crossref_primary_10_1186_s43042_025_00634_6 crossref_primary_10_18632_oncotarget_25661 crossref_primary_10_1111_j_1349_7006_2011_02033_x crossref_primary_10_3892_ol_2016_4913 crossref_primary_10_1186_1471_2407_9_155 crossref_primary_10_1007_s00464_016_5272_4 crossref_primary_10_18632_oncotarget_8492 crossref_primary_10_1007_s10787_010_0031_y crossref_primary_10_1155_2021_6657434 crossref_primary_10_1186_s13104_018_3204_1 crossref_primary_10_1002_ijc_34495 crossref_primary_10_1002_cncr_27602 crossref_primary_10_1007_s11845_009_0315_7 crossref_primary_10_1007_s12029_015_9700_9 crossref_primary_10_1097_MD_0000000000019362 crossref_primary_10_1007_s11596_018_1849_6 crossref_primary_10_5230_jgc_2017_17_e1 crossref_primary_10_3233_CBM_160593 crossref_primary_10_1093_carcin_bgq010 crossref_primary_10_1080_07357907_2016_1197237 crossref_primary_10_3109_09537104_2013_783689 crossref_primary_10_3109_09537104_2013_821607 crossref_primary_10_3892_ol_2015_3783 crossref_primary_10_3892_ol_2015_3784 crossref_primary_10_3389_fonc_2020_566804 crossref_primary_10_3748_wjg_v11_i45_7174 crossref_primary_10_1002_jbt_22371 crossref_primary_10_1007_s10238_010_0114_5 crossref_primary_10_1016_j_ccc_2011_01_002 crossref_primary_10_1017_S0007114512002954 crossref_primary_10_1038_s41598_021_84367_7 crossref_primary_10_1111_j_1349_7006_2011_01860_x crossref_primary_10_1093_cid_ciy331 crossref_primary_10_1007_s10120_018_0892_0 crossref_primary_10_1097_MD_0000000000027945 crossref_primary_10_1016_j_leukres_2014_07_006 crossref_primary_10_1093_jjco_hyaa099 crossref_primary_10_1016_j_ygyno_2015_09_017 crossref_primary_10_1245_s10434_018_6385_x crossref_primary_10_1007_s11605_020_04523_8 crossref_primary_10_1007_s10989_022_10399_w |
| Cites_doi | 10.1111/j.1365-3083.1995.tb03687.x 10.1093/oxfordjournals.epirev.a036288 10.1128/IAI.68.8.4769-4772.2000 10.1038/359843a0 10.1016/S0039-6060(98)70187-4 10.1074/jbc.270.47.28316 10.1007/s00428-002-0697-7 10.1023/A:1005912906436 10.1016/S0076-6879(84)05042-4 10.1016/S0959-8049(00)00018-6 10.1021/tx00045a020 10.1172/JCI117336 10.1038/sj.bjc.6690437 10.1136/gut.38.2.177 10.1016/S0959-8049(02)00596-8 10.1210/edrv.18.1.0287 10.1056/NEJM199412013312203 10.1016/S0140-6736(00)04046-0 10.1111/j.1476-5381.1993.tb12886.x 10.1007/BF02934081 10.1016/S0002-9610(02)01377-6 10.1023/A:1006918212866 10.1136/gut.42.3.351 10.1128/IAI.68.2.664-671.2000 10.1056/NEJM199011013231802 10.1111/j.1349-7006.1997.tb00314.x 10.1177/014107689608901205 10.1016/0304-3835(95)03895-4 10.1067/msy.2000.107265 10.1111/j.1365-3083.1984.tb00919.x 10.1007/BF00690598 10.1159/000236988 10.1093/oxfordjournals.bmb.a011682 10.1007/BF01740811 10.1161/01.CIR.94.7.1647 10.4049/jimmunol.152.8.4149 10.1056/NEJM199512283332608 10.1093/carcin/19.5.711 10.1016/1043-4666(92)90079-7 10.1007/s004230050202 10.1097/00004836-200305001-00009 10.1038/sj.bjp.0701691 10.1093/oxfordjournals.bmb.a011665 10.1056/NEJM199110173251603 10.1016/0003-2697(82)90118-X 10.1093/carcin/14.8.1555 10.1056/NEJM199902113400607 10.1093/oxfordjournals.bmb.a011664 10.1093/carcin/22.12.1947 10.1054/bjoc.1999.1253 |
| ClassificationCodes | R5 |
| ContentType | Journal Article |
| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved. 2004 |
| Copyright_xml | – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved. – notice: The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved. 2004 |
| DBID | 2RA 92L CQIGP W91 ~WA AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 2B. 4A8 92I 93N PSX TCJ 5PM |
| DOI | 10.3748/wjg.v10.i8.1115 |
| DatabaseName | 维普期刊资源整合服务平台 中文科技期刊数据库-CALIS站点 维普中文期刊数据库 维普中文医药期刊数据库 中文科技期刊数据库- 镜像站点 CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic Wanfang Data Journals - Hong Kong WANFANG Data Centre Wanfang Data Journals 万方数据期刊 - 香港版 China Online Journals (COJ) China Online Journals (COJ) PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2219-2840 |
| EndPage | 1120 |
| ExternalDocumentID | PMC4656344 wjg200408008 15069709 10_3748_wjg_v10_i8_1115 9710018 |
| Genre | Journal Article |
| GroupedDBID | --- 123 29R 2B. 2RA 2WC 36B 53G 5VR 8WL 92F 92I 92L 93N AAKDD ACGFO AENEX AFUIB ALMA_UNASSIGNED_HOLDINGS CCEZO CHBEP CIEJG CQIGP CS3 CW9 DIK DU5 E3Z EBS EJD EMB F5P FA0 FRP GX1 HYE M~E OK1 P2P RNS RPM SV3 TCJ TGQ TR2 W91 WFFXF XSB ~WA AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 4A8 PSX 5PM |
| ID | FETCH-LOGICAL-c444t-8a3dba3f02ed249a032b970cd7c106876961ef69699a80f3aa87ff2aecbcd5603 |
| ISSN | 1007-9327 |
| IngestDate | Tue Sep 30 16:38:36 EDT 2025 Thu May 29 04:01:26 EDT 2025 Wed Oct 01 14:01:22 EDT 2025 Wed Oct 16 00:47:21 EDT 2024 Wed Oct 01 02:54:14 EDT 2025 Thu Apr 24 23:07:15 EDT 2025 Tue Jan 07 06:24:55 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 8 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c444t-8a3dba3f02ed249a032b970cd7c106876961ef69699a80f3aa87ff2aecbcd5603 |
| Notes | 14-1219/R R730.43 R735.2 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Correspondence to: Dr. Nevin Ilhan, Flrat Universitesi, Flrat Tlp Merkezi, Biyokimya ve Klinik Biyokimya AD, 23119, Elazig, Turkey. drnilhan@yahoo.com Telephone: +90-424-2333555-2147 Fax: +90-424-2388660 Author contributions: All authors contributed equally to the work. |
| OpenAccessLink | https://www.wjgnet.com/1007-9327/full/v10/i8/1115.htm |
| PMID | 15069709 |
| PQID | 71812542 |
| PQPubID | 23479 |
| PageCount | 6 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_4656344 wanfang_journals_wjg200408008 proquest_miscellaneous_71812542 pubmed_primary_15069709 crossref_citationtrail_10_3748_wjg_v10_i8_1115 crossref_primary_10_3748_wjg_v10_i8_1115 chongqing_backfile_9710018 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2004-04-15 |
| PublicationDateYYYYMMDD | 2004-04-15 |
| PublicationDate_xml | – month: 04 year: 2004 text: 2004-04-15 day: 15 |
| PublicationDecade | 2000 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | World journal of gastroenterology : WJG |
| PublicationTitleAlternate | World Journal of Gastroenterology |
| PublicationTitle_FL | WORLD JOURNAL OF GASTROENTEROLOGY |
| PublicationYear | 2004 |
| Publisher | Department of Biochemistry and Clinical Biochemistry, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Department of General Surgery, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Division of Immunology, Firat University Firat Medical Centre, 23119, Elazig, Turkey Baishideng Publishing Group Inc |
| Publisher_xml | – name: Department of Biochemistry and Clinical Biochemistry, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Department of General Surgery, Firat University Firat Medical Centre, 23119, Elazig, Turkey%Division of Immunology, Firat University Firat Medical Centre, 23119, Elazig, Turkey – name: Baishideng Publishing Group Inc |
| References | ref13 ref57 ref12 ref56 ref15 ref59 ref14 ref58 ref53 ref52 ref11 ref55 ref10 ref54 ref17 ref16 ref19 ref18 ref51 ref50 ref46 ref45 ref48 ref47 ref42 ref41 ref44 ref43 ref49 ref8 ref7 ref9 ref4 ref3 ref6 ref5 ref40 ref35 ref34 ref37 ref36 ref31 ref30 ref33 ref32 ref2 ref1 ref39 ref38 ref24 ref23 ref26 ref25 ref20 ref22 ref21 ref28 ref27 ref29 ref60 ref61 |
| References_xml | – ident: ref1 – ident: ref59 doi: 10.1111/j.1365-3083.1995.tb03687.x – ident: ref20 doi: 10.1093/oxfordjournals.epirev.a036288 – ident: ref30 doi: 10.1128/IAI.68.8.4769-4772.2000 – ident: ref15 doi: 10.1038/359843a0 – ident: ref50 doi: 10.1016/S0039-6060(98)70187-4 – ident: ref16 doi: 10.1074/jbc.270.47.28316 – ident: ref4 doi: 10.1007/s00428-002-0697-7 – ident: ref40 doi: 10.1023/A:1005912906436 – ident: ref11 – ident: ref47 doi: 10.1016/S0076-6879(84)05042-4 – ident: ref42 doi: 10.1016/S0959-8049(00)00018-6 – ident: ref58 doi: 10.1021/tx00045a020 – ident: ref36 – ident: ref26 doi: 10.1172/JCI117336 – ident: ref53 doi: 10.1038/sj.bjc.6690437 – ident: ref25 doi: 10.1136/gut.38.2.177 – ident: ref34 doi: 10.1016/S0959-8049(02)00596-8 – ident: ref14 doi: 10.1210/edrv.18.1.0287 – ident: ref9 doi: 10.1056/NEJM199412013312203 – ident: ref52 doi: 10.1016/S0140-6736(00)04046-0 – ident: ref57 doi: 10.1111/j.1476-5381.1993.tb12886.x – ident: ref38 doi: 10.1007/BF02934081 – ident: ref5 doi: 10.1016/S0002-9610(02)01377-6 – ident: ref18 doi: 10.1023/A:1006918212866 – ident: ref37 doi: 10.1136/gut.42.3.351 – ident: ref3 – ident: ref31 doi: 10.1128/IAI.68.2.664-671.2000 – ident: ref19 doi: 10.1056/NEJM199011013231802 – ident: ref29 – ident: ref32 doi: 10.1111/j.1349-7006.1997.tb00314.x – ident: ref22 doi: 10.1177/014107689608901205 – ident: ref33 doi: 10.1016/0304-3835(95)03895-4 – ident: ref51 – ident: ref12 doi: 10.1067/msy.2000.107265 – ident: ref45 doi: 10.1111/j.1365-3083.1984.tb00919.x – ident: ref49 doi: 10.1007/BF00690598 – ident: ref8 doi: 10.1159/000236988 – ident: ref27 doi: 10.1093/oxfordjournals.bmb.a011682 – ident: ref43 doi: 10.1007/BF01740811 – ident: ref17 doi: 10.1161/01.CIR.94.7.1647 – ident: ref7 doi: 10.4049/jimmunol.152.8.4149 – ident: ref6 doi: 10.1056/NEJM199512283332608 – ident: ref55 – ident: ref41 doi: 10.1093/carcin/19.5.711 – ident: ref61 doi: 10.1016/1043-4666(92)90079-7 – ident: ref13 doi: 10.1007/s004230050202 – ident: ref2 doi: 10.1097/00004836-200305001-00009 – ident: ref39 doi: 10.1038/sj.bjp.0701691 – ident: ref28 doi: 10.1093/oxfordjournals.bmb.a011665 – ident: ref35 doi: 10.1056/NEJM199110173251603 – ident: ref46 – ident: ref48 doi: 10.1016/0003-2697(82)90118-X – ident: ref60 doi: 10.1093/carcin/14.8.1555 – ident: ref21 – ident: ref44 doi: 10.1056/NEJM199902113400607 – ident: ref56 – ident: ref23 doi: 10.1093/oxfordjournals.bmb.a011664 – ident: ref24 doi: 10.1093/carcin/22.12.1947 – ident: ref54 doi: 10.1054/bjoc.1999.1253 – ident: ref10 |
| SSID | ssj0023352 |
| Score | 2.0096579 |
| Snippet | The current study was to determine the serum/plasmalevels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide(NO), PCT and CRP in gastric carcinoma and... The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and... R5; AIM: The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma... AIM: The current study was to determine the serum/plasma levels of VEGF, IL-6, malondialdehyde (MDA), nitric oxide (NO), PCT and CRP in gastric carcinoma and... |
| SourceID | pubmedcentral wanfang proquest pubmed crossref chongqing |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1115 |
| SubjectTerms | Abdominal Pain - blood Abdominal Pain - diagnosis Aged Biomarkers Biomarkers, Tumor - blood C-Reactive Protein - metabolism Calcitonin - blood Calcitonin Gene-Related Peptide C反应蛋白 Female Gastric Cancer Helicobacter Infections - blood Helicobacter Infections - diagnosis Humans Interleukin-6 - blood Male Malnutrition - blood Malnutrition - diagnosis Malondialdehyde - blood Middle Aged Neoplasm Staging Nitric Oxide - blood Oxidative Stress Protein Precursors - blood Stomach Neoplasms - blood Stomach Neoplasms - pathology Vascular Endothelial Growth Factor A - blood Vomiting - blood Vomiting - diagnosis Weight Loss 氧化代谢物 白细胞介素-6 肿瘤标志物 胃癌 血管内皮生长因子 |
| Title | C-reactive protein, procalcitonin, interleukin-6, vascular endothelial growth factor and oxidative metabolites in diagnosis of infection and staging in patients with gastric cancer |
| URI | http://lib.cqvip.com/qk/84123X/20048/9710018.html https://www.ncbi.nlm.nih.gov/pubmed/15069709 https://www.proquest.com/docview/71812542 https://d.wanfangdata.com.cn/periodical/wjg200408008 https://pubmed.ncbi.nlm.nih.gov/PMC4656344 |
| Volume | 10 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVBFR databaseName: Free Medical Journals customDbUrl: eissn: 2219-2840 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0023352 issn: 1007-9327 databaseCode: DIK dateStart: 19980101 isFulltext: true titleUrlDefault: http://www.freemedicaljournals.com providerName: Flying Publisher – providerCode: PRVFQY databaseName: GFMER Free Medical Journals customDbUrl: eissn: 2219-2840 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0023352 issn: 1007-9327 databaseCode: GX1 dateStart: 0 isFulltext: true titleUrlDefault: http://www.gfmer.ch/Medical_journals/Free_medical.php providerName: Geneva Foundation for Medical Education and Research – providerCode: PRVAQN databaseName: PubMed Central (US National Library of Medicine) customDbUrl: eissn: 2219-2840 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0023352 issn: 1007-9327 databaseCode: RPM dateStart: 19970101 isFulltext: true titleUrlDefault: https://www.ncbi.nlm.nih.gov/pmc/ providerName: National Library of Medicine |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9NAEF61RUhcEIhXCoU9cECiDn5s_DiiCFQqteLQinKy1uu1kybdlNRuUX8XP5CZ3bVjkyBBL1aysddJ5tudh2e-IeRtmAQe-LKZI0LGHRaHgRNL8FI86QpYeyM_Y1jvfHQcHpyyw7PR2db2oJO1VFfZUNxurCu5i1RhDOSKVbL_Idl2UhiA1yBfOIKE4fhPMh47YPLpDeu95lswfACok_hcwFJVZgApIZZzWc-myglxoE0_lSrHCqw5hs1LcMiriW3Ao58pLH5Oc8MLfiErAAuWK5v0WZOfZ6hMmnQuk9UMxmZpy2QsZautnys5dggRmGUmbEawtYlNPk-HwkKfukCy0KVhiMKwxbfDtgvYl_nEhG2PQaurDaPCJGb3Rr_z6_q2hfcsq0EwWu9iKEX1gh86Z8aUf5oIH7aoxuar5VrUrp9HirkgDpiqRrdLPebDZu2AdnZ7ysDtgD7u7OygE0YdKwHMVHeTBkI2H4DNzXk5vIa303jYXNjB4-WFBiSSOyaRm6xUcZsg-fVojER2AWPb5J4fhaHfBKJsLAFL5fSDfPu7DGsV3v3DH_fWjafMjZA_ZLJQ5Q_4l_p22JpztZ4jfP-Gq4KrsmN-nTwiD63fRD-aRfCYbEn1hPxaLQBqF8A-7cF_n_bAv08b6NMO9KmBPjXQpwAI2kKfdqAPc9EW-nRR0Bb6-hoLfTyrgT5F6FMLfWqg_5Scfv50Mj5wbBsSRzDGKifmQZ7xoHB9mfss4W7gZ_BvijwSnhuCNZGEnizgmCQ8douA8zgqCp9LkYkcHIrgGdlRCyVfEJrzqIiihCd57jHfZRwcHDAwYk8Gnp9lowHZbQUEZqyYITlbmiADlxcPyLCRWCosgT_2kZmn4Mij5FOQfAqST6cxOvYw27v2gkvDXfP3U980EEhBv-BDQ67kor5KI3QBRswfkOcGEKupLKoGJOpBpT0Bmev7n6jpRDPYW2wPyJ4FVWo3mSv8YrjQ0ZGNd-8880vyYLVdvCI71bKWe-A9VNlrvY5-A6JaJwI |
| linkProvider | National Library of Medicine |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=C-reactive+protein%2C+procalcitonin%2C+interleukin-6%2C+vascular+endothelial+growth+factor+and+oxidative+metabolites+in+diagnosis+of+infection+and+staging+in+patients+with+gastric+cancer&rft.jtitle=World+journal+of+gastroenterology+%3A+WJG&rft.au=Ilhan%2C+Nevin&rft.au=Ilhan%2C+Necip&rft.au=Ilhan%2C+Yavuz&rft.au=Akbulut%2C+Handan&rft.date=2004-04-15&rft.pub=Baishideng+Publishing+Group+Inc&rft.issn=1007-9327&rft.eissn=2219-2840&rft.volume=10&rft.issue=8&rft.spage=1115&rft.epage=1120&rft_id=info:doi/10.3748%2Fwjg.v10.i8.1115&rft_id=info%3Apmid%2F15069709&rft.externalDocID=PMC4656344 |
| thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fimage.cqvip.com%2Fvip1000%2Fqk%2F84123X%2F84123X.jpg http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fwjg%2Fwjg.jpg |