Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions

Fabulous Fluorine: The synthesis of fluorinated products 1 and 2 by [2+2] photocycloaddition was readily feasible after optimization of the irradiation conditions. The electron‐deficient trifluoroolefin unit reacted intramolecularly to products 1 (nine examples, d.r.>95:5). The reaction was also...

Full description

Saved in:

Bibliographic Details
Published in	Angewandte Chemie International Edition Vol. 51; no. 40; pp. 10169 - 10172
Main Authors	Fort, Diego A., Woltering, Thomas J., Nettekoven, Matthias, Knust, Henner, Bach, Thorsten
Format	Journal Article
Language	English
Published	Weinheim WILEY-VCH Verlag 01.10.2012 WILEY‐VCH Verlag Wiley Wiley Subscription Services, Inc
Edition	International ed. in English
Subjects	Chemistry Chemistry, Multidisciplinary cycloaddition diastereoselectivity fluorine Irradiation photochemistry Physical Sciences Science & Technology strained molecules strained molecules MECHANISM diastereoselectivity REGIOSELECTIVITY MOLECULES MEDICINAL CHEMISTRY ALKENES KETONES cycloaddition photochemistry VALENCE ISOMERS OLEFINS DERIVATIVES fluorine
Online Access	Get full text
ISSN	1433-7851 1521-3773
DOI	10.1002/anie.201204080

Cover

Abstract	Fabulous Fluorine: The synthesis of fluorinated products 1 and 2 by [2+2] photocycloaddition was readily feasible after optimization of the irradiation conditions. The electron‐deficient trifluoroolefin unit reacted intramolecularly to products 1 (nine examples, d.r.>95:5). The reaction was also investigated after modification of position 2 of the side chain both with one or two fluoro substituents (e.g. to yield product 2).
AbstractList	Fabulous Fluorine: The synthesis of fluorinated products 1 and 2 by [2+2] photocycloaddition was readily feasible after optimization of the irradiation conditions. The electron‐deficient trifluoroolefin unit reacted intramolecularly to products 1 (nine examples, d.r.>95:5). The reaction was also investigated after modification of position 2 of the side chain both with one or two fluoro substituents (e.g. to yield product 2). Fabulous Fluorine: The synthesis of fluorinated products 1 and 2 by [2+2]photocycloaddition was readily feasible after optimization of the irradiation conditions. The electron-deficient trifluoroolefin unit reacted intramolecularly to products 1 (nine examples, d.r.>95:5). The reaction was also investigated after modification of position2 of the side chain both with one or two fluoro substituents (e.g. to yield product 2).
Author	Woltering, Thomas J. Fort, Diego A. Nettekoven, Matthias Knust, Henner Bach, Thorsten
Author_xml	– sequence: 1 givenname: Diego A. surname: Fort fullname: Fort, Diego A. organization: Lehrstuhl für Organische Chemie I, Technische Universität München, Lichtenbergstr. 4, 85747 Garching (Germany) http://www.oc1.ch.tum.de/home_en/ – sequence: 2 givenname: Thomas J. surname: Woltering fullname: Woltering, Thomas J. organization: Discovery Chemistry, PRCB, F. Hoffmann-La Roche AG, Grenzacherstrasse 124, 4070 Basel (Switzerland) – sequence: 3 givenname: Matthias surname: Nettekoven fullname: Nettekoven, Matthias organization: Discovery Chemistry, PRCB, F. Hoffmann-La Roche AG, Grenzacherstrasse 124, 4070 Basel (Switzerland) – sequence: 4 givenname: Henner surname: Knust fullname: Knust, Henner organization: Discovery Chemistry, PRCB, F. Hoffmann-La Roche AG, Grenzacherstrasse 124, 4070 Basel (Switzerland) – sequence: 5 givenname: Thorsten surname: Bach fullname: Bach, Thorsten email: thorsten.bach@ch.tum.de organization: Lehrstuhl für Organische Chemie I, Technische Universität München, Lichtenbergstr. 4, 85747 Garching (Germany) http://www.oc1.ch.tum.de/home_en/
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/22962009$$D View this record in MEDLINE/PubMed
BookMark	eNqNkUuLFDEURoOMOA_dupQCl0O1eVUlWQ7tPBqaUewWFyIhlUqYjNXJTFKF1s7N_FF_iSm6pxFBdJW7OOfem_sdgwMfvAHgJYIzBCF-o7wzMwwRhhRy-AQcoQqjkjBGDnJNCSkZr9AhOE7pNvOcw_oZOMRY1BhCcQT0avT9jUkuFcEWF90QovOqN22xjk6PunO6WGllbejaVDRjsfB9VJvQGT10Khaf8Sn-8vPHw_ub0IeJD6ptXe-CLz4YpaciPQdPreqSebF7T8DHi_P1_KpcvrtczM-WpaaUwtIwZoVCEDGjkdFt3aBG1aLhmCFhm9ZQyxrKuBCEQ1tZ3oiWVMJYTFFeUJET8Hrb9y6G-8GkXt6GIfo8UiLEUMV4DXGmXu2oodmYVt5Ft1FxlI83yQDfAt9ME2zSznht9hiEkECBOGK5onDuejV9ch4G32f19P_VTNMtrWNIKRor9a5bPrHrJIJyylhOGct9xlmb_aE9DvirIHZbuc6M_6Dl2fXi_He33Lou9eb73lXxq6wZYZX8dH0pCVrSFXq7lhX5BTglx8Y
CODEN	ACIEAY
CitedBy_id	crossref_primary_10_1021_acs_orglett_0c01065 crossref_primary_10_1002_chin_201311094 crossref_primary_10_1002_ejoc_201403620 crossref_primary_10_1039_c3ra42106f crossref_primary_10_1002_anie_201407832 crossref_primary_10_1021_acs_joc_7b02910 crossref_primary_10_1021_acs_joc_6b01620 crossref_primary_10_1021_acs_jafc_3c05758 crossref_primary_10_1021_acs_joc_6b01066 crossref_primary_10_1002_chem_201603303 crossref_primary_10_1016_j_jphotochem_2015_09_020 crossref_primary_10_1039_c3cc40757h crossref_primary_10_1039_c3ob40645h crossref_primary_10_1002_ange_201808578 crossref_primary_10_1021_acs_joc_8b00077 crossref_primary_10_1016_j_arabjc_2015_11_004 crossref_primary_10_3987_COM_13_S_S_67 crossref_primary_10_1002_ange_201407832 crossref_primary_10_1021_jo401126p crossref_primary_10_3390_molecules18032942 crossref_primary_10_1002_adsc_201700062 crossref_primary_10_1021_acs_joc_7b01678 crossref_primary_10_1021_acs_chemrev_5b00723 crossref_primary_10_1002_chem_202102621 crossref_primary_10_1016_j_tetlet_2013_06_106 crossref_primary_10_1002_anie_201808578 crossref_primary_10_1021_acs_joc_8b00238 crossref_primary_10_1021_acs_orglett_9b00309
Cites_doi	10.1055/s-1998-2054 10.1021/cr60115a001 10.1002/anie.201102027 10.1002/9780470133521.ch2 10.1126/science.4038558 10.1246/bcsj.53.764 10.1021/ol902381w 10.1039/B711844A 10.1002/macp.1993.021940802 10.1002/anie.200352171 10.1002/chem.201000036 10.1002/ange.201102027 10.1016/S0022-1139(00)83610-6 10.1039/B610213C 10.1002/9783527628193.ch6 10.1039/B613985J 10.1021/ja00316a087 10.1002/ange.200352171 10.1002/352760393X 10.1021/jo00075a040 10.1016/0040-4020(82)80229-9 10.1021/jo961196h 10.1002/9780470988589 10.1021/jm8015014 10.1002/jlac.19254440112 10.1007/BF00714432 10.1016/j.tet.2011.10.002 10.1021/ja00422a066 10.1021/cr980379w 10.1248/cpb.40.2319 10.1021/cr00017a001 10.1002/cber.19911240442 10.1021/jo00189a017 10.1002/ejoc.200400551 10.1016/S0022-1139(02)00201-4 10.1002/cbic.200301023 10.1055/s-0028-1087806 10.1021/jm800219f 10.1002/ange.19260390504 10.1016/j.jfluchem.2006.01.011 10.1016/j.jfluchem.2006.06.007 10.1021/jo201066d 10.1021/ja00103a003 10.1016/j.jfluchem.2006.05.006 10.1021/jo010828j 10.1055/s-0029-1218793 10.1055/s-2006-941571 10.1039/b610213c 10.1039/b613985j 10.1039/b711844a
ContentType	Journal Article
Copyright	Copyright © 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Copyright_xml	– notice: Copyright © 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim – notice: Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
DBID	BSCLL AAYXX CITATION 17B 1KM 1KN BLEPL DTL EGQ GKHJH NPM 7TM K9.
DOI	10.1002/anie.201204080
DatabaseName	Istex CrossRef Web of Knowledge Index Chemicus Current Chemical Reactions Web of Science Core Collection Science Citation Index Expanded Web of Science Primary (SCIE, SSCI & AHCI) Web of Science - Science Citation Index Expanded - 2012 PubMed Nucleic Acids Abstracts ProQuest Health & Medical Complete (Alumni)
DatabaseTitle	CrossRef Web of Science PubMed ProQuest Health & Medical Complete (Alumni) Nucleic Acids Abstracts
DatabaseTitleList	ProQuest Health & Medical Complete (Alumni)
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 1KN name: Current Chemical Reactions url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/woscc/search-with-editions?editions=WOS.CCR sourceTypes: Enrichment Source Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Chemistry
EISSN	1521-3773
Edition	International ed. in English
EndPage	10172
ExternalDocumentID	2819549371 22962009 000309181700040 10_1002_anie_201204080 ANIE201204080 ark_67375_WNG_31L4S1DT_5
Genre	shortCommunication Journal Article
GrantInformation_xml	– fundername: Roche Postdoc Fellowship (RPF) Program
GroupedDBID	--- -DZ -~X .3N .GA .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 23M 31~ 33P 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5RE 5VS 66C 6TJ 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHQN AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABDBF ABEML ABIJN ABJNI ABLJU ABPPZ ABPVW ACAHQ ACBWZ ACCZN ACFBH ACGFS ACIWK ACNCT ACPOU ACPRK ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN AEIGN AEIMD AETEA AEUYR AEYWJ AFBPY AFFNX AFFPM AFGKR AFRAH AFWVQ AFZJQ AGQPQ AGYGG AHBTC AHMBA AITYG AIURR AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ATUGU AUFTA AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BSCLL BTSUX BY8 CS3 D-E D-F D0L DCZOG DPXWK DR1 DR2 DRFUL DRSTM EBS EJD F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.T H.X HBH HF~ HGLYW HHY HHZ HVGLF HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M53 MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB O66 O9- OIG P2P P2W P2X P4D PQQKQ Q.N Q11 QB0 QRW R.K RNS ROL RX1 RYL SUPJJ TN5 UB1 UPT V2E W8V W99 WBFHL WBKPD WH7 WIB WIH WIK WJL WOHZO WQJ WXSBR WYISQ XG1 XPP XSW XV2 YZZ ZZTAW ~IA ~KM ~WT AAHHS ACCFJ ADZOD AEEZP AEQDE AEUQT AFPWT AIWBW AJBDE RWI VQA WRC .GJ .HR 186 9M8 AAYJJ AAYOK AAYXX ABDPE ABEFU ADXHL AGCDD AGHNM AI. ASPBG AVWKF CITATION H~9 MVM NHB OHT PALCI RIWAO RJQFR RWH S10 SAMSI UQL VH1 WHG XOL YYP ZCG ZE2 ZGI ZXP ZY4 17B 1KM 1KN BLEPL DTL GROUPED_WOS_SCIENCE_CITATION_INDEX_EXPANDED GROUPED_WOS_WEB_OF_SCIENCE NPM 7TM K9.
ID	FETCH-LOGICAL-c4440-e77f9a1017ec1ecd6b1ba69b82719fbde4f7b47899380f5f8b9d359ef241affa3
IEDL.DBID	DR2
ISICitedReferencesCount	30
ISICitedReferencesURI	https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=CitingArticles&UT=000309181700040
ISSN	1433-7851
IngestDate	Fri Jul 25 10:23:57 EDT 2025 Thu Apr 03 07:03:33 EDT 2025 Wed Jul 09 08:40:16 EDT 2025 Fri Sep 26 20:33:10 EDT 2025 Tue Jul 01 02:53:05 EDT 2025 Thu Apr 24 23:05:26 EDT 2025 Wed Jan 22 16:38:03 EST 2025 Sun Sep 21 06:18:46 EDT 2025
IsPeerReviewed	true
IsScholarly	true
Issue	40
Keywords	strained molecules MECHANISM diastereoselectivity REGIOSELECTIVITY MOLECULES MEDICINAL CHEMISTRY ALKENES KETONES cycloaddition photochemistry VALENCE ISOMERS OLEFINS DERIVATIVES fluorine
Language	English
License	http://onlinelibrary.wiley.com/termsAndConditions#vor
LinkModel	DirectLink
LogoURL	https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg
MergedId	FETCHMERGED-LOGICAL-c4440-e77f9a1017ec1ecd6b1ba69b82719fbde4f7b47899380f5f8b9d359ef241affa3
Notes	ark:/67375/WNG-31L4S1DT-5 ArticleID:ANIE201204080 D.A.F. wishes to acknowledge funding by the Roche Postdoc Fellowship (RPF) Program. istex:E1E89017FFB5009B066D06FFCDB5EB9ED7F0C798 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14
ORCID	0000-0002-1342-0202
PMID	22962009
PQID	1171578602
PQPubID	946352
PageCount	4
ParticipantIDs	crossref_citationtrail_10_1002_anie_201204080 istex_primary_ark_67375_WNG_31L4S1DT_5 proquest_journals_1171578602 crossref_primary_10_1002_anie_201204080 pubmed_primary_22962009 webofscience_primary_000309181700040CitationCount wiley_primary_10_1002_anie_201204080_ANIE201204080 webofscience_primary_000309181700040
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	October 1, 2012
PublicationDateYYYYMMDD	2012-10-01
PublicationDate_xml	– month: 10 year: 2012 text: October 1, 2012 day: 01
PublicationDecade	2010
PublicationPlace	Weinheim
PublicationPlace_xml	– name: Weinheim – name: WEINHEIM – name: Germany
PublicationTitle	Angewandte Chemie International Edition
PublicationTitleAbbrev	ANGEW CHEM INT EDIT
PublicationTitleAlternate	Angew. Chem. Int. Ed
PublicationYear	2012
Publisher	WILEY-VCH Verlag WILEY‐VCH Verlag Wiley Wiley Subscription Services, Inc
Publisher_xml	– name: WILEY-VCH Verlag – name: WILEY‐VCH Verlag – name: Wiley – name: Wiley Subscription Services, Inc
References	Fluorinated Heterocyclic Compounds (Ed.: V. A. Petrov), Wiley, Hoboken, 2009 M. Fleck, C. Yang, T. Wada, Y. Inoue, T. Bach, Chem. Commun. 2007, 822-824 A. J. Wexler, J. S. Swenton, J. Am. Chem. Soc. 1976, 98, 1602-1604 D. I. Schuster, G. N. Lem, A. Kaprinidis, Chem. Rev. 1993, 93, 3-22. W. K. Hagmann, J. Med. Chem. 2008, 51, 4359-4369 W. R. Li, S. T. Lin, N.-M. Hsu, M. S. Chern, J. Org. Chem. 2002, 67, 4702-4706. T. I. Gorbunova, A. Y. Zapevalov, V. I. Saloutin, Russ. Chem. Bull. 1995, 44, 1470-1473 P. Margaretha in Molecular and Supramolecular Photochemistry, Vol. 12 (Eds.: A. G. Griesbeck, J. Mattay), Marcel Dekker, New York, 2005, pp. 211-237 A. Verley, Bull. Soc. Chim. Fr. 1925, 37, 537 R. A. Correa, N. Jing, J. Org. Chem. 1993, 58, 6406-6409. S. L. Schreiber, Science 1985, 227, 857-863 J. P. Pete in CRC Handbook of Organic Photochemistry and Photobiology, 2nd ed. (Eds.: W. Horspool, F. Lenci), CRC, Boca Raton, 2004, pp. 71/1-71/14 M. T. Crimmins, T. L. Reinhold, Org. React. 1993, 44, 297-588. H.-J. Böhm, D. Banner, S. Bendels, M. Kansy, B. Kuhn, K. Müller, U. Obst-Sander, M. Stahl, ChemBioChem 2004, 5, 637-643 P. Kirsch, Modern Fluoroorganic Chemistry: Synthesis Reactivity, Applications, Wiley-VCH, Weinheim, 2004. M. M. Kremlev, I. S. Mazny, Y. L. Yagupolskii, J. Fluorine Chem. 1991, 54, 100 S. Fustero, J. F. Sanz-Cervera, J. L. Aceña, M. Sánchez-Roselló, Synlett 2009, 525-549 L. E. Zimmer, C. Sparr, R. Gilmour, Angew. Chem. 2011, 123, 12062-12074 J. P. Bégué, D. Bonnet-Delpon, J. Fluorine Chem. 2006, 127, 992-1012 S. Jarosz, A. Zamojski, Tetrahedron 1982, 38, 1453-1456 J. P. Hehn, C. Müller, T. Bach in Handbook of Synthetic Photochemistry (Eds.: A. Albini, M. Fagnoni), Wiley-VCH, Weinheim, 2009, pp. 171-215 W. P. Dailey, D. M. Lemal, J. Am. Chem. Soc. 1984, 106, 1169-1170 J.-P. Pete, Adv. Photochem. 1996, 21, 135-216 H. Kimoto, K. Takahashi, H. Muramatsu, Bull. Chem. Soc. Jpn. 1980, 53, 764-769 C. Gauzy, B. Saby, E. Pereira, S. Faure, D. J. Aitken, Synlett 2006, 1394-1398. A. J. Wexler, R. J. Balchunis, J. S. Swenton, J. Org. Chem. 1984, 49, 2733-2738 J. P. Hehn, D. Gamba-Sánchez, M. Kemmler, M. Fleck, B. Basler, T. Bach, Synthesis 2010, 2308-2312 J. Mattay, R. Conrads, R. Hoffmann in Methoden der Organischen Chemie (Houben-Weyl) 4te Aufl., Band E 21c (Eds.: G. Helmchen, R. W. Hoffmann, J. Mulzer, E. Schaumann), Thieme, Stuttgart, 1995, pp. 3085-3132 R. Weixler, J. P. Hehn, T. Bach, J. Org. Chem. 2011, 76, 5924-5935. S. A. Fleming in Molecular and Supramolecular Photochemistry, Vol. 12 (Eds.: A. G. Griesbeck, J. Mattay), Marcel Dekker, New York, 2005, pp. 141-160 D. Andrew, D. J. Hastings, A. C. Weedon, J. Am. Chem. Soc. 1994, 116, 10870-10882. A. Mengel, O. Reiser, Chem. Rev. 1999, 99, 1191-1223. S. Purser, P. R. Moore, S. Swallow, V. Gouverneur, Chem. Soc. Rev. 2008, 37, 320-330 A. K. Podichetty, S. Wagner, S. Schröer, A. Faust, O. Schober, M. Schäfers, K. Kopka, G. Haufe, J. Med. Chem. 2009, 52, 3484-3495. Angew. Chem. Int. Ed. 2003, 42, 4824-4826 T. Bach, Synthesis 1998, 683-703 J. Yin, M. A. Huffman, K. M. Conrad, J. D. Armstrong III, J. Org. Chem. 1996, 61, 8805-8810. T. Iwaoka, N. Katagiri, M. Sato, C. Kaneko, Chem. Pharm. Bull. 1992, 40, 2319-2324 A. N. Tkachenko, D. S. Radchenko, P. K. Mykhailiuk, O. O. Grygorenko, I. V. Komarov, Org. Lett. 2009, 11, 5674-5676. A. Arnone, D. D. DesMareau, B. Novo, V. A. Petrov, M. Pregnolato, G. Resnati, J. Org. Chem. 1996, 61, 8805-8810. T. Hiyama, Organofluorine Compounds, Springer, Berlin, 2010 C. Žagar, H.-D. Scharf, Chem. Ber. 1991, 124, 967-969. H. Meerwein, R. Schmidt, Justus Liebigs Ann. Chem. 1925, 444, 221-238 M. Kemmler, T. Bach, Angew. Chem. 2003, 115, 4973-4975 K. Uneyama, Organofluorine Chemistry, Blackwell, Oxford, 2006 Y. Tada, M. Sato, N. Takeno, Y. Nakacho, K. Shigehara, Makromol. Chem. 1993, 194, 2163-2171. F. M. D. Ismail, J. Fluorine Chem. 2002, 118, 27-33 K. L. Kirk, J. Fluorine Chem. 2006, 127, 1013-1029 M. Kemmler, T. Bach, Eur. J. Org. Chem. 2004, 4582-4595 D. O'Hagan, Chem. Soc. Rev. 2008, 37, 308-319 Angew. Chem. Int. Ed. 2011, 50, 11860-11871. C. Isanbor, D. O'Hagan, J. Fluorine Chem. 2006, 127, 303-319 M. Fleck, T. Bach, Chem. Eur. J. 2010, 16, 6015-6032 A. G. O'Brien, Tetrahedron 2011, 67, 9639-9667 W. Ponndorf, Angew. Chem. 1926, 39, 138-143 G. R. Waitkins, C. W. Clark, Chem. Rev. 1945, 36, 235-289. 1994; 116 2010; 16 1982; 38 2010 1984; 49 1991; 54 1993; 44 1984; 106 1945; 36 2009 1998 2008; 37 2002; 118 2007 2006 2004; 5 1995 2011; 76 2005 1926; 39 2004 1985; 227 2011 2011; 123 50 2008; 51 1976; 98 1993; 58 2009; 11 1925; 37 2009; 52 2003 2003; 115 42 1991; 124 1980; 53 1993; 93 2002; 67 1995; 44 1996; 61 1993; 194 1999; 99 2011; 67 1925; 444 2006; 127 1996; 21 1992; 40 e_1_2_2_24_2 e_1_2_2_47_2 e_1_2_2_4_2 e_1_2_2_49_2 e_1_2_2_6_2 e_1_2_2_20_2 e_1_2_2_62_2 e_1_2_2_41_2 e_1_2_2_64_2 e_1_2_2_41_3 e_1_2_2_8_2 e_1_2_2_28_2 e_1_2_2_43_2 e_1_2_2_66_2 e_1_2_2_60_2 Crimmins M. T. (e_1_2_2_27_2) 1993; 44 Gauzy C. (e_1_2_2_38_2) 2006 e_1_2_2_13_2 e_1_2_2_36_2 e_1_2_2_59_2 Hiyama T. (e_1_2_2_2_2) 2010 e_1_2_2_11_2 Fleming S. A. (e_1_2_2_21_2) 2005 e_1_2_2_51_2 e_1_2_2_19_2 e_1_2_2_30_2 e_1_2_2_53_2 e_1_2_2_17_2 e_1_2_2_32_2 e_1_2_2_55_2 e_1_2_2_15_2 e_1_2_2_34_2 Margaretha P. (e_1_2_2_22_2) 2005 Pete J. P. (e_1_2_2_23_2) 2004 Hehn J. P. (e_1_2_2_45_2) 2010 e_1_2_2_3_2 e_1_2_2_48_2 e_1_2_2_5_2 Verley A. (e_1_2_2_57_2) 1925; 37 e_1_2_2_1_2 (e_1_2_2_16_2) 2009 Mattay J. (e_1_2_2_26_2) 1995 e_1_2_2_40_2 e_1_2_2_61_2 e_1_2_2_29_2 e_1_2_2_42_2 e_1_2_2_63_2 e_1_2_2_7_2 e_1_2_2_44_2 e_1_2_2_65_2 e_1_2_2_9_2 e_1_2_2_25_2 e_1_2_2_46_2 e_1_2_2_12_2 e_1_2_2_37_2 e_1_2_2_58_2 e_1_2_2_10_2 e_1_2_2_39_2 e_1_2_2_50_2 e_1_2_2_18_3 e_1_2_2_18_2 e_1_2_2_31_2 e_1_2_2_52_2 e_1_2_2_33_2 e_1_2_2_54_2 e_1_2_2_14_2 e_1_2_2_35_2 e_1_2_2_56_2 Pete, J.-P. (000309181700040.38) 1996; 21 Tkachenko, AN (WOS:000272461800027) 2009; 11 WAITKINS, GR (WOS:A1945UP00300001) 1945; 36 Fleck, M (WOS:000244252600012) 2007 Uneyama, K. (000309181700040.47) 2006 Kirk, KL (WOS:000239874500002) 2006; 127 Gauzy, C (WOS:000238142900023) 2006 Bach, T (WOS:000073687900001) 1998 ANDREW, D (WOS:A1994PX30900003) 1994; 116 JAROSZ, S (WOS:A1982NW72700013) 1982; 38 Pete, J. P. (000309181700040.37) 2004 Begue, JP (WOS:000239874500001) 2006; 127 WEXLER, A (WOS:A1976BK06700066) 1976; 98 SCHREIBER, SL (WOS:A1985ABT5400009) 1985; 227 Hehn, JP (WOS:000280299200026) 2010 SCHUSTER, DI (WOS:A1993KL64800002) 1993; 93 Bohm, HJ (WOS:000221270500007) 2004; 5 KIMOTO, H (WOS:A1980JL24000039) 1980; 53 WEXLER, AJ (WOS:A1984TC06400017) 1984; 49 Yin, J. (000309181700040.53) 1996; 61 Li, WR (WOS:000176600400010) 2002; 67 O'Hagan, D (WOS:000252411800006) 2008; 37 Weixler, R (WOS:000293252600006) 2011; 76 Mengel, A (WOS:000080452700006) 1999; 99 Margaretha, P (CCC:000228482200008) 2005; 12 Zimmer, L. E. (000309181700040.56) 2011; 123 Hehn, J. P. (000309181700040.17) 2009 Kemmler, M (WOS:000186128300025) 2003; 42 Hiyama, T. (000309181700040.18) 2010 Hagmann, WK (WOS:000258289800001) 2008; 51 Kemmler, M. (000309181700040.25) 2003; 115 Ismail, FMD (WOS:000179614100004) 2002; 118 ZAGAR, C (WOS:A1991FJ64500041) 1991; 124 Podichetty, AK (WOS:000266718600009) 2009; 52 Verley, A. (000309181700040.48) 1925; 37 Zimmer, LE (WOS:000298085000009) 2011; 50 Meerwein, H (WOS:000200663100011) 1925; 444 IWAOKA, T (WOS:A1992JR95500015) 1992; 40 Kirsch, P. (000309181700040.28) 2004 CORREA, RA (WOS:A1993MF51600040) 1993; 58 Ponndorf, W. (000309181700040.41) 1926; 39 O'Brien, AG (WOS:000297485800001) 2011; 67 TADA, Y (WOS:A1993LP87400002) 1993; 194 Kremlev, M. M. (000309181700040.29) 1991; 54 Mattay, J. (000309181700040.32) 1995; E 21c Arnone, A (WOS:A1996VY22000022) 1996; 61 Crimmins, M. T. (000309181700040.7) 1993; 44 DAILEY, WP (WOS:A1984SE19900087) 1984; 106 Fustero, S (WOS:000264658300002) 2009 Purser, S (WOS:000252411800007) 2008; 37 Fleck, M (WOS:000278596600024) 2010; 16 GORBUNOVA, TI (WOS:A1995TG56600020) 1995; 44 Petrov, V. A. (000309181700040.39) 2009 Kemmler, M (WOS:000225420600009) 2004; 2004 Fleming, SA (CCC:000228482200005) 2005; 12 Isanbor, C (WOS:000236926300001) 2006; 127
References_xml	– reference: K. L. Kirk, J. Fluorine Chem. 2006, 127, 1013-1029; – reference: A. N. Tkachenko, D. S. Radchenko, P. K. Mykhailiuk, O. O. Grygorenko, I. V. Komarov, Org. Lett. 2009, 11, 5674-5676. – reference: S. Purser, P. R. Moore, S. Swallow, V. Gouverneur, Chem. Soc. Rev. 2008, 37, 320-330; – reference: K. Uneyama, Organofluorine Chemistry, Blackwell, Oxford, 2006; – reference: M. Kemmler, T. Bach, Eur. J. Org. Chem. 2004, 4582-4595; – reference: W. Ponndorf, Angew. Chem. 1926, 39, 138-143; – reference: J. Yin, M. A. Huffman, K. M. Conrad, J. D. Armstrong III, J. Org. Chem. 1996, 61, 8805-8810. – reference: H.-J. Böhm, D. Banner, S. Bendels, M. Kansy, B. Kuhn, K. Müller, U. Obst-Sander, M. Stahl, ChemBioChem 2004, 5, 637-643; – reference: M. Fleck, C. Yang, T. Wada, Y. Inoue, T. Bach, Chem. Commun. 2007, 822-824; – reference: C. Žagar, H.-D. Scharf, Chem. Ber. 1991, 124, 967-969. – reference: T. Hiyama, Organofluorine Compounds, Springer, Berlin, 2010; – reference: J. P. Hehn, C. Müller, T. Bach in Handbook of Synthetic Photochemistry (Eds.: A. Albini, M. Fagnoni), Wiley-VCH, Weinheim, 2009, pp. 171-215; – reference: W. R. Li, S. T. Lin, N.-M. Hsu, M. S. Chern, J. Org. Chem. 2002, 67, 4702-4706. – reference: D. O'Hagan, Chem. Soc. Rev. 2008, 37, 308-319; – reference: A. K. Podichetty, S. Wagner, S. Schröer, A. Faust, O. Schober, M. Schäfers, K. Kopka, G. Haufe, J. Med. Chem. 2009, 52, 3484-3495. – reference: A. J. Wexler, R. J. Balchunis, J. S. Swenton, J. Org. Chem. 1984, 49, 2733-2738; – reference: M. T. Crimmins, T. L. Reinhold, Org. React. 1993, 44, 297-588. – reference: J. P. Pete in CRC Handbook of Organic Photochemistry and Photobiology, 2nd ed. (Eds.: W. Horspool, F. Lenci), CRC, Boca Raton, 2004, pp. 71/1-71/14; – reference: Angew. Chem. Int. Ed. 2011, 50, 11860-11871. – reference: T. I. Gorbunova, A. Y. Zapevalov, V. I. Saloutin, Russ. Chem. Bull. 1995, 44, 1470-1473; – reference: H. Kimoto, K. Takahashi, H. Muramatsu, Bull. Chem. Soc. Jpn. 1980, 53, 764-769; – reference: A. J. Wexler, J. S. Swenton, J. Am. Chem. Soc. 1976, 98, 1602-1604; – reference: P. Kirsch, Modern Fluoroorganic Chemistry: Synthesis Reactivity, Applications, Wiley-VCH, Weinheim, 2004. – reference: P. Margaretha in Molecular and Supramolecular Photochemistry, Vol. 12 (Eds.: A. G. Griesbeck, J. Mattay), Marcel Dekker, New York, 2005, pp. 211-237; – reference: A. Verley, Bull. Soc. Chim. Fr. 1925, 37, 537; – reference: C. Isanbor, D. O'Hagan, J. Fluorine Chem. 2006, 127, 303-319; – reference: J.-P. Pete, Adv. Photochem. 1996, 21, 135-216; – reference: T. Iwaoka, N. Katagiri, M. Sato, C. Kaneko, Chem. Pharm. Bull. 1992, 40, 2319-2324; – reference: F. M. D. Ismail, J. Fluorine Chem. 2002, 118, 27-33; – reference: W. P. Dailey, D. M. Lemal, J. Am. Chem. Soc. 1984, 106, 1169-1170; – reference: S. Fustero, J. F. Sanz-Cervera, J. L. Aceña, M. Sánchez-Roselló, Synlett 2009, 525-549; – reference: R. A. Correa, N. Jing, J. Org. Chem. 1993, 58, 6406-6409. – reference: Y. Tada, M. Sato, N. Takeno, Y. Nakacho, K. Shigehara, Makromol. Chem. 1993, 194, 2163-2171. – reference: G. R. Waitkins, C. W. Clark, Chem. Rev. 1945, 36, 235-289. – reference: L. E. Zimmer, C. Sparr, R. Gilmour, Angew. Chem. 2011, 123, 12062-12074; – reference: S. A. Fleming in Molecular and Supramolecular Photochemistry, Vol. 12 (Eds.: A. G. Griesbeck, J. Mattay), Marcel Dekker, New York, 2005, pp. 141-160; – reference: D. Andrew, D. J. Hastings, A. C. Weedon, J. Am. Chem. Soc. 1994, 116, 10870-10882. – reference: J. P. Bégué, D. Bonnet-Delpon, J. Fluorine Chem. 2006, 127, 992-1012; – reference: J. Mattay, R. Conrads, R. Hoffmann in Methoden der Organischen Chemie (Houben-Weyl) 4te Aufl., Band E 21c (Eds.: G. Helmchen, R. W. Hoffmann, J. Mulzer, E. Schaumann), Thieme, Stuttgart, 1995, pp. 3085-3132; – reference: M. M. Kremlev, I. S. Mazny, Y. L. Yagupolskii, J. Fluorine Chem. 1991, 54, 100; – reference: R. Weixler, J. P. Hehn, T. Bach, J. Org. Chem. 2011, 76, 5924-5935. – reference: D. I. Schuster, G. N. Lem, A. Kaprinidis, Chem. Rev. 1993, 93, 3-22. – reference: W. K. Hagmann, J. Med. Chem. 2008, 51, 4359-4369; – reference: M. Fleck, T. Bach, Chem. Eur. J. 2010, 16, 6015-6032; – reference: C. Gauzy, B. Saby, E. Pereira, S. Faure, D. J. Aitken, Synlett 2006, 1394-1398. – reference: Fluorinated Heterocyclic Compounds (Ed.: V. A. Petrov), Wiley, Hoboken, 2009; – reference: T. Bach, Synthesis 1998, 683-703; – reference: A. Mengel, O. Reiser, Chem. Rev. 1999, 99, 1191-1223. – reference: Angew. Chem. Int. Ed. 2003, 42, 4824-4826; – reference: H. Meerwein, R. Schmidt, Justus Liebigs Ann. Chem. 1925, 444, 221-238; – reference: S. Jarosz, A. Zamojski, Tetrahedron 1982, 38, 1453-1456; – reference: S. L. Schreiber, Science 1985, 227, 857-863; – reference: A. Arnone, D. D. DesMareau, B. Novo, V. A. Petrov, M. Pregnolato, G. Resnati, J. Org. Chem. 1996, 61, 8805-8810. – reference: M. Kemmler, T. Bach, Angew. Chem. 2003, 115, 4973-4975; – reference: J. P. Hehn, D. Gamba-Sánchez, M. Kemmler, M. Fleck, B. Basler, T. Bach, Synthesis 2010, 2308-2312; – reference: A. G. O'Brien, Tetrahedron 2011, 67, 9639-9667; – volume: 5 start-page: 637 year: 2004 end-page: 643 publication-title: ChemBioChem – volume: 444 start-page: 221 year: 1925 end-page: 238 publication-title: Justus Liebigs Ann. Chem. – volume: 37 start-page: 537 year: 1925 publication-title: Bull. Soc. Chim. Fr. – year: 2009 – volume: 44 start-page: 297 year: 1993 end-page: 588 publication-title: Org. React. – volume: 93 start-page: 3 year: 1993 end-page: 22 publication-title: Chem. Rev. – volume: 16 start-page: 6015 year: 2010 end-page: 6032 publication-title: Chem. Eur. J. – volume: 227 start-page: 857 year: 1985 end-page: 863 publication-title: Science – start-page: 2308 year: 2010 end-page: 2312 publication-title: Synthesis – volume: 36 start-page: 235 year: 1945 end-page: 289 publication-title: Chem. Rev. – volume: 67 start-page: 9639 year: 2011 end-page: 9667 publication-title: Tetrahedron – volume: 106 start-page: 1169 year: 1984 end-page: 1170 publication-title: J. Am. Chem. Soc. – volume: 40 start-page: 2319 year: 1992 end-page: 2324 publication-title: Chem. Pharm. Bull. – volume: 39 start-page: 138 year: 1926 end-page: 143 publication-title: Angew. Chem. – volume: 37 start-page: 320 year: 2008 end-page: 330 publication-title: Chem. Soc. Rev. – volume: 54 start-page: 100 year: 1991 publication-title: J. Fluorine Chem. – volume: 61 start-page: 8805 year: 1996 end-page: 8810 publication-title: J. Org. Chem. – volume: 124 start-page: 967 year: 1991 end-page: 969 publication-title: Chem. Ber. – start-page: 211 year: 2005 end-page: 237 – year: 2004 – volume: 67 start-page: 4702 year: 2002 end-page: 4706 publication-title: J. Org. Chem. – volume: 118 start-page: 27 year: 2002 end-page: 33 publication-title: J. Fluorine Chem. – start-page: 4582 year: 2004 end-page: 4595 publication-title: Eur. J. Org. Chem. – volume: 123 50 start-page: 12062 11860 year: 2011 2011 end-page: 12074 11871 publication-title: Angew. Chem. Angew. Chem. Int. Ed. – start-page: 683 year: 1998 end-page: 703 publication-title: Synthesis – volume: 76 start-page: 5924 year: 2011 end-page: 5935 publication-title: J. Org. Chem. – volume: 127 start-page: 303 year: 2006 end-page: 319 publication-title: J. Fluorine Chem. – volume: 127 start-page: 1013 year: 2006 end-page: 1029 publication-title: J. Fluorine Chem. – start-page: 525 year: 2009 end-page: 549 publication-title: Synlett – start-page: 1394 year: 2006 end-page: 1398 publication-title: Synlett – volume: 11 start-page: 5674 year: 2009 end-page: 5676 publication-title: Org. Lett. – volume: 37 start-page: 308 year: 2008 end-page: 319 publication-title: Chem. Soc. Rev. – volume: 38 start-page: 1453 year: 1982 end-page: 1456 publication-title: Tetrahedron – start-page: 171 year: 2009 end-page: 215 – volume: 116 start-page: 10870 year: 1994 end-page: 10882 publication-title: J. Am. Chem. Soc. – volume: 99 start-page: 1191 year: 1999 end-page: 1223 publication-title: Chem. Rev. – volume: 44 start-page: 1470 year: 1995 end-page: 1473 publication-title: Russ. Chem. Bull. – volume: 49 start-page: 2733 year: 1984 end-page: 2738 publication-title: J. Org. Chem. – volume: 194 start-page: 2163 year: 1993 end-page: 2171 publication-title: Makromol. Chem. – start-page: 3085 year: 1995 end-page: 3132 – year: 2010 – start-page: 71 year: 2004 end-page: 71 – volume: 53 start-page: 764 year: 1980 end-page: 769 publication-title: Bull. Chem. Soc. Jpn. – volume: 127 start-page: 992 year: 2006 end-page: 1012 publication-title: J. Fluorine Chem. – start-page: 141 year: 2005 end-page: 160 – volume: 115 42 start-page: 4973 4824 year: 2003 2003 end-page: 4975 4826 publication-title: Angew. Chem. Angew. Chem. Int. Ed. – volume: 98 start-page: 1602 year: 1976 end-page: 1604 publication-title: J. Am. Chem. Soc. – volume: 51 start-page: 4359 year: 2008 end-page: 4369 publication-title: J. Med. Chem. – volume: 52 start-page: 3484 year: 2009 end-page: 3495 publication-title: J. Med. Chem. – year: 2006 – volume: 58 start-page: 6406 year: 1993 end-page: 6409 publication-title: J. Org. Chem. – start-page: 822 year: 2007 end-page: 824 publication-title: Chem. Commun. – volume: 21 start-page: 135 year: 1996 end-page: 216 publication-title: Adv. Photochem. – ident: e_1_2_2_24_2 doi: 10.1055/s-1998-2054 – ident: e_1_2_2_53_2 doi: 10.1021/cr60115a001 – ident: e_1_2_2_18_3 doi: 10.1002/anie.201102027 – ident: e_1_2_2_25_2 doi: 10.1002/9780470133521.ch2 – ident: e_1_2_2_62_2 doi: 10.1126/science.4038558 – ident: e_1_2_2_28_2 – ident: e_1_2_2_32_2 doi: 10.1246/bcsj.53.764 – ident: e_1_2_2_39_2 doi: 10.1021/ol902381w – volume-title: Fluorinated Heterocyclic Compounds year: 2009 ident: e_1_2_2_16_2 – ident: e_1_2_2_3_2 doi: 10.1039/B711844A – start-page: 141 volume-title: Molecular and Supramolecular Photochemistry, Vol. 12 year: 2005 ident: e_1_2_2_21_2 – ident: e_1_2_2_51_2 doi: 10.1002/macp.1993.021940802 – ident: e_1_2_2_19_2 – ident: e_1_2_2_41_3 doi: 10.1002/anie.200352171 – ident: e_1_2_2_44_2 doi: 10.1002/chem.201000036 – ident: e_1_2_2_18_2 doi: 10.1002/ange.201102027 – ident: e_1_2_2_48_2 doi: 10.1016/S0022-1139(00)83610-6 – ident: e_1_2_2_13_2 doi: 10.1039/B610213C – ident: e_1_2_2_60_2 – ident: e_1_2_2_20_2 doi: 10.1002/9783527628193.ch6 – ident: e_1_2_2_43_2 doi: 10.1039/B613985J – ident: e_1_2_2_29_2 doi: 10.1021/ja00316a087 – ident: e_1_2_2_41_2 doi: 10.1002/ange.200352171 – start-page: 211 volume-title: Molecular and Supramolecular Photochemistry, Vol. 12 year: 2005 ident: e_1_2_2_22_2 – ident: e_1_2_2_5_2 doi: 10.1002/352760393X – ident: e_1_2_2_40_2 – ident: e_1_2_2_30_2 doi: 10.1021/jo00075a040 – start-page: 1394 year: 2006 ident: e_1_2_2_38_2 publication-title: Synlett – start-page: 2308 year: 2010 ident: e_1_2_2_45_2 publication-title: Synthesis – ident: e_1_2_2_61_2 doi: 10.1016/0040-4020(82)80229-9 – ident: e_1_2_2_59_2 doi: 10.1021/jo961196h – ident: e_1_2_2_4_2 doi: 10.1002/9780470988589 – ident: e_1_2_2_14_2 doi: 10.1021/jm8015014 – ident: e_1_2_2_56_2 doi: 10.1002/jlac.19254440112 – volume: 44 start-page: 297 year: 1993 ident: e_1_2_2_27_2 publication-title: Org. React. – ident: e_1_2_2_49_2 doi: 10.1007/BF00714432 – ident: e_1_2_2_64_2 – ident: e_1_2_2_65_2 doi: 10.1016/j.tet.2011.10.002 – ident: e_1_2_2_35_2 doi: 10.1021/ja00422a066 – ident: e_1_2_2_66_2 doi: 10.1021/cr980379w – ident: e_1_2_2_37_2 doi: 10.1248/cpb.40.2319 – ident: e_1_2_2_54_2 doi: 10.1021/cr00017a001 – start-page: 71 volume-title: CRC Handbook of Organic Photochemistry and Photobiology, 2nd year: 2004 ident: e_1_2_2_23_2 – ident: e_1_2_2_63_2 doi: 10.1002/cber.19911240442 – ident: e_1_2_2_36_2 doi: 10.1021/jo00189a017 – ident: e_1_2_2_55_2 – start-page: 3085 volume-title: Methoden der Organischen Chemie (Houben‐Weyl) 4te Aufl. year: 1995 ident: e_1_2_2_26_2 – ident: e_1_2_2_6_2 – ident: e_1_2_2_42_2 doi: 10.1002/ejoc.200400551 – ident: e_1_2_2_7_2 doi: 10.1016/S0022-1139(02)00201-4 – ident: e_1_2_2_8_2 doi: 10.1002/cbic.200301023 – ident: e_1_2_2_17_2 doi: 10.1055/s-0028-1087806 – ident: e_1_2_2_12_2 doi: 10.1021/jm800219f – ident: e_1_2_2_47_2 – volume: 37 start-page: 537 year: 1925 ident: e_1_2_2_57_2 publication-title: Bull. Soc. Chim. Fr. – ident: e_1_2_2_58_2 doi: 10.1002/ange.19260390504 – ident: e_1_2_2_1_2 – ident: e_1_2_2_11_2 doi: 10.1016/j.jfluchem.2006.01.011 – volume-title: Organofluorine Compounds year: 2010 ident: e_1_2_2_2_2 – ident: e_1_2_2_50_2 doi: 10.1021/jo961196h – ident: e_1_2_2_10_2 doi: 10.1016/j.jfluchem.2006.06.007 – ident: e_1_2_2_46_2 doi: 10.1021/jo201066d – ident: e_1_2_2_33_2 doi: 10.1021/ja00103a003 – ident: e_1_2_2_34_2 – ident: e_1_2_2_9_2 doi: 10.1016/j.jfluchem.2006.05.006 – ident: e_1_2_2_31_2 – ident: e_1_2_2_52_2 doi: 10.1021/jo010828j – ident: e_1_2_2_15_2 – volume: 44 start-page: 1470 year: 1995 ident: WOS:A1995TG56600020 article-title: SYNTHESIS OF OXIRANES BASED ON 1,1,2,3,3-PENTAFLUORO-1,5-HEXADIENE publication-title: RUSSIAN CHEMICAL BULLETIN – volume: 37 start-page: 537 year: 1925 ident: 000309181700040.48 publication-title: Bull. Soc. Chim. Fr – volume: 11 start-page: 5674 year: 2009 ident: WOS:000272461800027 article-title: 4-Fluoro-2,4-methanoproline publication-title: ORGANIC LETTERS doi: 10.1021/ol902381w – volume: 36 start-page: 235 year: 1945 ident: WOS:A1945UP00300001 article-title: SELENIUM DIOXIDE - PREPARATION, PROPERTIES, AND USE AS OXIDIZING AGENT publication-title: CHEMICAL REVIEWS – start-page: 2308 year: 2010 ident: WOS:000280299200026 article-title: [2+2]-Photocycloaddition Reactions of Tetronic Acid Esters and Amides publication-title: SYNTHESIS-STUTTGART doi: 10.1055/s-0029-1218793 – start-page: 525 year: 2009 ident: WOS:000264658300002 article-title: Nitrogen-Containing Organofluorine Derivatives: An Overview publication-title: SYNLETT doi: 10.1055/s-0028-1087806 – volume: 40 start-page: 2319 year: 1992 ident: WOS:A1992JR95500015 article-title: USE OF 1,3-DIOXIN-4-ONES AND RELATED-COMPOUNDS IN SYNTHESIS .38. USE OF 1,3-DIOXIN-4-ONES HAVING A FLUORINE OR TRIFLUOROMETHYL GROUP AT THE 5-POSITION AS PI-2 COMPONENTS IN [2 + 2]-PHOTOCYCLOADDITION AND DIELS-ALDER REACTIONS publication-title: CHEMICAL & PHARMACEUTICAL BULLETIN – start-page: 1394 year: 2006 ident: WOS:000238142900023 article-title: The [2+2] photocycloaddition of uracil derivatives with ethylene as a general route to cis-cyclobutane beta-amino acids publication-title: SYNLETT doi: 10.1055/s-2006-941571 – volume: 115 start-page: 4973 year: 2003 ident: 000309181700040.25 publication-title: Angew. Chem – volume: 127 start-page: 1013 year: 2006 ident: WOS:000239874500002 article-title: Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules publication-title: JOURNAL OF FLUORINE CHEMISTRY doi: 10.1016/j.jfluchem.2006.06.007 – volume: 42 start-page: 4824 year: 2003 ident: WOS:000186128300025 article-title: [2+2] photocycloaddition of tetronates publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.200352171 – volume: 37 start-page: 320 year: 2008 ident: WOS:000252411800007 article-title: Fluorine in medicinal chemistry publication-title: CHEMICAL SOCIETY REVIEWS doi: 10.1039/b610213c – volume: 227 start-page: 857 year: 1985 ident: WOS:A1985ABT5400009 article-title: [2+2] PHOTOCYCLOADDITIONS IN THE SYNTHESIS OF CHIRAL MOLECULES publication-title: SCIENCE – volume: 5 start-page: 637 year: 2004 ident: WOS:000221270500007 article-title: Fluorine in medicinal chemistry publication-title: CHEMBIOCHEM doi: 10.1002/cbic.200301023 – volume: 99 start-page: 1191 year: 1999 ident: WOS:000080452700006 article-title: Around and beyond Cram's rule publication-title: CHEMICAL REVIEWS – volume: 50 start-page: 11860 year: 2011 ident: WOS:000298085000009 article-title: Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.201102027 – volume: 116 start-page: 10870 year: 1994 ident: WOS:A1994PX30900003 article-title: THE MECHANISM OF THE PHOTOCHEMICAL CYCLOADDITION REACTION BETWEEN 2-CYCLOPENTENONE AND POLAR ALKENES - TRAPPING OF TRIPLET 1,4-BIRADICAL INTERMEDIATES WITH HYDROGEN SELENIDE publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY – volume: 194 start-page: 2163 year: 1993 ident: WOS:A1993LP87400002 article-title: ION-CONDUCTION OF LITHIUM FLUOROALKYLSULFONATES IN OLIGO(OXYETHYLENE)-BRANCHED POLY(PHOSPHAZENE) publication-title: MAKROMOLEKULARE CHEMIE-MACROMOLECULAR CHEMISTRY AND PHYSICS – start-page: 171 year: 2009 ident: 000309181700040.17 publication-title: Handbook of Synthetic Photochemistry – volume: 21 start-page: 135 year: 1996 ident: 000309181700040.38 publication-title: Adv. Photochem – volume: 118 start-page: 27 year: 2002 ident: WOS:000179614100004 article-title: Important fluorinated drugs in experimental and clinical use publication-title: JOURNAL OF FLUORINE CHEMISTRY – volume: 123 start-page: 12062 year: 2011 ident: 000309181700040.56 publication-title: Angew. Chem – volume: 53 start-page: 764 year: 1980 ident: WOS:A1980JL24000039 article-title: PHOTO-CYCLOADDITION OF INDENE TO CHLOROFLUOROETHYLENES AND SOME REACTIONS CONCERNING THE ADDUCTS publication-title: BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN – volume: 54 start-page: 100 year: 1991 ident: 000309181700040.29 publication-title: J. Fluorine Chem – volume: 67 start-page: 9639 year: 2011 ident: WOS:000297485800001 article-title: Recent advances in acyclic stereocontrol publication-title: TETRAHEDRON doi: 10.1016/j.tet.2011.10.002 – start-page: 822 year: 2007 ident: WOS:000244252600012 article-title: Regioselective [2+2]-photocycloaddition reactions of chiral tetronates - influence of temperature, pressure, and reaction medium publication-title: CHEMICAL COMMUNICATIONS doi: 10.1039/b613985j – year: 2004 ident: 000309181700040.28 publication-title: Modern Fluoroorganic Chemistry: Synthesis Reactivity, Applications – volume: 16 start-page: 6015 year: 2010 ident: WOS:000278596600024 article-title: Total Synthesis of Punctaporonin C by a Regio- and Stereoselective [2+2]-Photocycloaddition publication-title: CHEMISTRY-A EUROPEAN JOURNAL doi: 10.1002/chem.201000036 – year: 2006 ident: 000309181700040.47 publication-title: Organofluorine Chemistry – volume: 39 start-page: 138 year: 1926 ident: 000309181700040.41 publication-title: Angew. Chem – start-page: 683 year: 1998 ident: WOS:000073687900001 article-title: Stereoselective intermolecular [2+2]-photocycloaddition reactions and their application in synthesis publication-title: SYNTHESIS-STUTTGART – volume: 49 start-page: 2733 year: 1984 ident: WOS:A1984TC06400017 article-title: PRODUCT STUDIES OF THE PHOTOCYCLOADDITION REACTIONS OF 5-CHLOROURACIL AND 5-FLUOROURACIL DERIVATIVES AND OLEFINS - AN INTERESTING AND USEFUL EFFECT OF FLUORINE ON REGIOSELECTIVITY publication-title: JOURNAL OF ORGANIC CHEMISTRY – start-page: 71/1 year: 2004 ident: 000309181700040.37 publication-title: CRC Handbook of Organic Photochemistry and Photobiology – volume: E 21c start-page: 3085 year: 1995 ident: 000309181700040.32 publication-title: Methoden der Organischen Chemie (Houben-Weyl) – volume: 58 start-page: 6406 year: 1993 ident: WOS:A1993MF51600040 article-title: INTERRELATIONSHIPS AMONG C6F10 VALENCE ISOMERS publication-title: JOURNAL OF ORGANIC CHEMISTRY – volume: 127 start-page: 303 year: 2006 ident: WOS:000236926300001 article-title: Fluorine in medicinal chemistry: A review of anti-cancer agents publication-title: JOURNAL OF FLUORINE CHEMISTRY doi: 10.1016/j.jfluchem.2006.01.011 – year: 2009 ident: 000309181700040.39 publication-title: Fluorinated Heterocyclic Compounds – volume: 124 start-page: 967 year: 1991 ident: WOS:A1991FJ64500041 article-title: CHIRAL INDUCTION IN PHOTOCHEMICAL-REACTIONS .13. THE PATERNO-BUCHI REACTION OF ACHIRAL AND CHIRAL ACYL CYANIDES WITH FURAN publication-title: CHEMISCHE BERICHTE – volume: 98 start-page: 1602 year: 1976 ident: WOS:A1976BK06700066 article-title: FLUORINE CONTROL OF REGIOSELECTIVITY IN PHOTOCYCLOADDITION REACTIONS - DIRECT FUNCTIONALIZATION OF URACIL VIA A NOVEL 1,4-FRAGMENTATION publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY – volume: 12 start-page: 141 year: 2005 ident: CCC:000228482200005 article-title: Photocycloaddition of alkenes to excited alkenes publication-title: SYNTHETIC ORGANIC PHOTOCHEMISTRY – volume: 106 start-page: 1169 year: 1984 ident: WOS:A1984SE19900087 article-title: PERFLUOROTROPILIDENE VALENCE ISOMERS AND THE PERFLUOROTROPYLIUM ION publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY – volume: 12 start-page: 211 year: 2005 ident: CCC:000228482200008 article-title: Photocycloaddition of cycloalk-2-enones to alkenes publication-title: SYNTHETIC ORGANIC PHOTOCHEMISTRY – volume: 61 start-page: 8805 year: 1996 ident: WOS:A1996VY22000022 article-title: Selective epoxidation of olefins by perfluoro-cis-2,3-dialkyloxaziridines publication-title: JOURNAL OF ORGANIC CHEMISTRY – volume: 127 start-page: 992 year: 2006 ident: WOS:000239874500001 article-title: Recent advances (1995-2005) in fluorinated pharmaceuticals based on natural products publication-title: JOURNAL OF FLUORINE CHEMISTRY doi: 10.1016/j.jfluchem.2006.05.006 – volume: 76 start-page: 5924 year: 2011 ident: WOS:000293252600006 article-title: On the Regioselectivity of the Intramolecular [2+2]-Photocycloaddition of Alk-3-enyl Tetronates publication-title: JOURNAL OF ORGANIC CHEMISTRY doi: 10.1021/jo201066d – volume: 93 start-page: 3 year: 1993 ident: WOS:A1993KL64800002 article-title: NEW INSIGHTS INTO AN OLD MECHANISM - [2 + 2] PHOTOCYCLOADDITION OF ENONES TO ALKENES publication-title: CHEMICAL REVIEWS – volume: 52 start-page: 3484 year: 2009 ident: WOS:000266718600009 article-title: Fluorinated Isatin Derivatives. Part 2. New N-Substituted 5-Pyrrolidinylsulfonyl Isatins as Potential Tools for Molecular Imaging of Caspases in Apoptosis publication-title: JOURNAL OF MEDICINAL CHEMISTRY doi: 10.1021/jm8015014 – year: 2010 ident: 000309181700040.18 publication-title: Organofluorine Compounds – volume: 44 start-page: 297 year: 1993 ident: 000309181700040.7 publication-title: Org. React – volume: 2004 start-page: 4582 year: 2004 ident: WOS:000225420600009 article-title: Inter- and intramolecular [2+2]-photocycloaddition of tetronates - Stereoselectivity, mechanism, scope and synthetic applications publication-title: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY doi: 10.1002/ejoc.200400551 – volume: 67 start-page: 4702 year: 2002 ident: WOS:000176600400010 article-title: Efficient total synthesis of pulchellalactam, a CD45 protein tyrosine phosphatase inhibitor publication-title: JOURNAL OF ORGANIC CHEMISTRY doi: 10.1021/jo010828j – volume: 38 start-page: 1453 year: 1982 ident: WOS:A1982NW72700013 article-title: ASYMMETRIC PHOTOCYCLOADDITION BETWEEN FURAN AND OPTICALLY-ACTIVE KETONES publication-title: TETRAHEDRON – volume: 51 start-page: 4359 year: 2008 ident: WOS:000258289800001 article-title: The many roles for fluorine in medicinal chemistry publication-title: JOURNAL OF MEDICINAL CHEMISTRY doi: 10.1021/jm800219f – volume: 61 start-page: 8805 year: 1996 ident: 000309181700040.53 publication-title: J. Org. Chem – volume: 37 start-page: 308 year: 2008 ident: WOS:000252411800006 article-title: Understanding organofluorine chemistry. An introduction to the C-F bond publication-title: CHEMICAL SOCIETY REVIEWS doi: 10.1039/b711844a – volume: 444 start-page: 221 year: 1925 ident: WOS:000200663100011 article-title: A new process for the reduction of aldehydes and ketones publication-title: JUSTUS LIEBIGS ANNALEN DER CHEMIE
SSID	ssj0028806
Score	2.2255466
Snippet	Fabulous Fluorine: The synthesis of fluorinated products 1 and 2 by [2+2] photocycloaddition was readily feasible after optimization of the irradiation... Fabulous Fluorine: The synthesis of fluorinated products 1 and 2 by [2+2]photocycloaddition was readily feasible after optimization of the irradiation...
Source	Web of Science
SourceID	proquest pubmed webofscience crossref wiley istex
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	10169
SubjectTerms	Chemistry Chemistry, Multidisciplinary cycloaddition diastereoselectivity fluorine Irradiation photochemistry Physical Sciences Science & Technology strained molecules
Title	Synthesis of Fluorinated Tricyclic Scaffolds by Intramolecular [2+2] Photocycloaddition Reactions
URI	https://api.istex.fr/ark:/67375/WNG-31L4S1DT-5/fulltext.pdf https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fanie.201204080 http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=FullRecord&UT=000309181700040 https://www.ncbi.nlm.nih.gov/pubmed/22962009 https://www.proquest.com/docview/1171578602
Volume	51
WOS	000309181700040
WOSCitedRecordID	wos000309181700040
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB6hcoALb2hoQT5UcEBp14-8jtW2S4tghbpbUQmhyE9RddlUTVZiOXHhj_JL8ORFtwKB4JYoYyt2PtufnZlvALY8E4odz0Ros4EMBbU6THViw4Qbo01kdZRivPObcXxwLF6dRCeXovgbfYj-wA1HRj1f4wCXqtz5KRqKEdjomsU8DFPctFMeo3j-3lGvH8U8OJvwIs5DzELfqTYO2M5q8ZVV6Tp28OdfUc4rq9Mqoa1XpNFtkF1bGkeUs-1Fpbb1lysyj__T2Dtwq6WrZLfB1124Zuf34MawyxJ3H_RkOfccsjwtSeHIaLZAhz7PXw2Z-hl2qWenmky0dK6YmZKoJTnE0-RPXVJe8p69YB--f_329mNRFWhfoIcTooUc2SboonwAx6P96fAgbBM3hFrgv2KbJC6TONit9l_fxIoqGWcqZQnNnDJWuESJxG_1eDpwkUtVZniUWefphH8hyR_C2ryY23UgMRMRF1L5arjw9ESmnlKlyhimtXYqDiDsPlyuW1VzTK4xyxs9ZpZj1-V91wXwvLc_b_Q8fmv5rMZBbyYvztALLonyd-OXOaevxYTuTfMogM0OKHk7AZSooU79ZBgPWACPGvD0FTGWxfhTKoCty2jqn9f71IzW0on-VQKgf2M2bFuPWgZVAKyG0x_amO-OD_f7u8f_UmgDbuJ149-4CWvVxcI-8TytUk_rsfgDGfsz1A
linkProvider	Wiley-Blackwell
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB6h9lAuvB8pBXyo4IDSbmzndayWLruwXaHuViAhZMUvUXXZVE1WYjlx4Y_yS_DkBVuBQHBMMo5i57P92Z75BmDXMaHIspT7Ju1lPg-M8hMVGz9mWisdGhUmGO98NImGJ_zl27D1JsRYmFofottww55RjdfYwXFDev-HaiiGYKNvFnU4TNyqfbM6pENedNwpSFEHzzrAiDEf89C3uo09ur9efm1e2sQm_vQr0nlpflqntNWcNLgOsq1N7Ypytrcs5Z76fEno8b-qewOuNYyVHNQQuwlXzOIWbPXbRHG3QU1XC0cji9OC5JYM5kv06XMUVpOZG2RXan6qyFRl1uZzXRC5IiPcUP7Y5uUl7-gz-v7bl6-vP-RljvY5OjkhYMixqeMuijtwMjic9Yd-k7vBVxyPi00c2zTD_m6UA4COZCCzKJUJjYPUSm24jSWP3WqPJT0b2kSmmoWpsY5RuA_K2F3YWOQLcx9IRHnIeCbdaxh3DCVLHKtKpNZUKWVl5IHf_jmhGmFzzK8xF7UkMxXYdKJrOg-edvbntaTHby2fVEDozLKLM3SEi0PxZvJCsGDMp8HzmQg92GmRIpoxoEAZ9cCNh1GPenCvRk_3IkrTCM-lPNj9GU7d82qpmgaVeqL7FA-CvzHrN7VHOYPSA1rh6Q91FAeT0WF3tf0vhR7D1nB2NBbj0eTVA7iK92t3xx3YKC-W5qGjbaV8VHXM705pN_I
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwEB6hVgIuvB-BAj5UcEBpN7bzOlbbLl0oq6q7FZUQsuKXWnW7qZqsxHLiwh_ll-DJi24FAsExydiKnc_2Z2fmG4B1x4Qiy1Lum7SX-Twwyk9UbPyYaa10aFSYYLzz-1G0e8jfHoVHl6L4a32I7sANR0Y1X-MAP9d286doKEZgo2sWdTBM3KZ9lUdurURadNAJSFGHzjq-iDEf09C3so09urlcfmlZWsUe_vwrznlleVpmtNWSNLgNWduY2hPldGNeyg315YrO4_-09g7cavgq2aoBdheumdk9uNFv08TdBzVezByJLE4KklsymM7Ro88RWE0mbopdqOmJImOVWZtPdUHkggzxOPmszcpLPtLX9NP3r9_2j_MyR_scXZwQLuTA1FEXxQM4HOxM-rt-k7nBVxx_Fps4tmmGo90o9_l1JAOZRalMaBykVmrDbSx57PZ6LOnZ0CYy1SxMjXV8wr1Qxh7CyiyfmcdAIspDxjPpqmHc8ZMscZwqkVpTpZSVkQd---GEamTNMbvGVNSCzFRg14mu6zx41dmf14Iev7V8WeGgM8suTtENLg7Fh9EbwYI9Pg62JyL0YK0FimhmgAJF1AM3GzpMevCoBk9XEaVphH-lPFi_jKbuebVRTYNKO9G9igfB35j1m9ajmEHpAa3g9Ic2iq3RcKe7evIvhV7A9f3tgdgbjt49hZt4u_Z1XIOV8mJunjnOVsrn1bD8AXIfNqE
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Synthesis+of+Fluorinated+Tricyclic+Scaffolds+by+Intramolecular+%5B2%2B2%5D%E2%80%85Photocycloaddition+Reactions&rft.jtitle=Angewandte+Chemie+International+Edition&rft.au=Fort%2C+Diego+A.&rft.au=Woltering%2C+Thomas+J.&rft.au=Nettekoven%2C+Matthias&rft.au=Knust%2C+Henner&rft.date=2012-10-01&rft.pub=WILEY%E2%80%90VCH+Verlag&rft.issn=1433-7851&rft.eissn=1521-3773&rft.volume=51&rft.issue=40&rft.spage=10169&rft.epage=10172&rft_id=info:doi/10.1002%2Fanie.201204080&rft.externalDBID=10.1002%252Fanie.201204080&rft.externalDocID=ANIE201204080
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1433-7851&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1433-7851&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1433-7851&client=summon