IL‐2 therapy preferentially expands adoptively transferred donor‐specific Tregs improving skin allograft survival - Ratnasothy, Kulachelvy; Jacob, Jacintha; Tung, Sim; Boardman, Dominic; Lechler, Robert Ian; Sanchez-Fueyo, Alberto; Martinez‐Llordella, Marc; Lombardi, Giovanna (American journal of transplantation, 2019)
Keywords: Adoptive Transfer; Allografts; Animal models; Animals; antigen presentation/recognition; Autoimmune diseases; basic (laboratory) research/science; Brief Communication; Brief Communications; CTLA-4 protein; Drug Synergism; Graft Survival; Histocompatibility - immunology; immune regulation; immunobiology; Immunological tolerance; Immunoregulation; immunosuppression/immune modulation; Immunotherapy; Interleukin-2 - administration & dosage; Lymph nodes; Lymphocytes T; Major histocompatibility complex; Mice; Mice, Inbred CBA; Mice, Transgenic; organ transplantation in general; Receptors, Antigen, T-Cell - immunology; Receptors, Antigen, T-Cell - metabolism; Skin; Skin Transplantation - methods; T cell biology; T-Lymphocytes, Regulatory - immunology; T-Lymphocytes, Regulatory - pathology; T-Lymphocytes, Regulatory - transplantation; Tissue Donors; tolerance; translational research/science; Transplantation; Transplantation Tolerance - immunology; Transplantation, Homologous; Transplants & implants; translational research/science; antigen presentation/recognition; immunosuppression/immune modulation; organ transplantation in general; T cell biology; graft survival; immunobiology; immune regulation; tolerance; basic (laboratory) research/science