Nogo-A/Pir-B/TrkB Signaling Pathway Activation Inhibits Neuronal Survival and Axonal Regeneration After Experimental Intracerebral Hemorrhage in Rats - Liu, Yinlong; Ma, Chao; Li, Haiying; Shen, Haitao; Li, Xiang; Fu, Xi’an; Wu, Jiang; Chen, Gang (Journal of molecular neuroscience, 2019)
Keywords: Animals; Apoptosis; Biomedical and Life Sciences; Biomedicine; Brain; Brain - pathology; Brain injury; Carbazoles - toxicity; Cell Biology; Cell Death; Cerebral Hemorrhage - chemically induced; Cerebral Hemorrhage - drug therapy; Cerebral Hemorrhage - pathology; Cerebral Hemorrhage - physiopathology; Cognition Disorders - etiology; Cognition Disorders - prevention & control; Cognitive ability; Head injuries; Hemorrhage; Immunofluorescence; Indole Alkaloids - toxicity; Kinases; Lesions; Male; Maze Learning; Motor Activity; Myelin; Nerve Tissue Proteins - metabolism; Neurochemistry; Neurology; Neuronal Outgrowth - physiology; Neurons - pathology; Neurons - physiology; Neuroprotective Agents - therapeutic use; Neurosciences; Nogo protein; Nogo Proteins - biosynthesis; Nogo Proteins - physiology; Proteins; Proteomics; Quinolines - therapeutic use; Rats; Rats, Sprague-Dawley; Receptor, trkB - physiology; Receptors, Immunologic - biosynthesis; Receptors, Immunologic - physiology; Regeneration; Signal Transduction; Survival; TrkB receptors; Tropomyosin; Up-Regulation; Growth-associated protein 43; Nogo-A; Neuron cell death; Intracerebral hemorrhage; Tropomyosin receptor kinase B; Axonal regeneration