17β-Estradiol and/or estrogen receptor alpha signaling blocks protein phosphatase 1 mediated ISO induced cardiac hypertrophy - Fang, Hsin-Yuan; Hung, Meng-Yu; Lin, Yueh-Min; Pandey, Sudhir; Chang, Chia-Chien; Lin, Kuan-Ho; Shen, Chia-Yao; Viswanadha, Vijaya Padma; Kuo, Wei-Wen; Huang, Chih-Yang (PloS one, 2018)
Keywords: 17β-Estradiol; Activation; Adenosine triphosphatase; Animals; Apoptosis; Biology and Life Sciences; Ca2+-transporting ATPase; Calcium; Calcium (reticular); Calcium - metabolism; Calcium ions; Cardiac function; Cardiac muscle; Cardiomegaly - chemically induced; Cardiomegaly - metabolism; Cardiomegaly - prevention & control; Cardiomyocytes; Cell Enlargement - drug effects; Cell Line; Cell size; Estradiol - metabolism; Estradiol - pharmacology; Estrogen Receptor alpha - antagonists & inhibitors; Estrogen Receptor alpha - metabolism; Estrogen receptors; Estrogens; Gene expression; Heart; Heart failure; Hormone replacement therapy; Hospitals; Hypertrophy; Inhibitors; Isoproterenol; Isoproterenol - toxicity; Medical research; Medicine and Health Sciences; Melatonin; Models, Cardiovascular; Molecular modelling; Musculoskeletal system; Myocytes, Cardiac - drug effects; Myocytes, Cardiac - metabolism; Myocytes, Cardiac - pathology; Phosphatase; Phospholamban; Phosphoprotein phosphatase; Phosphorylation; Protein phosphatase; Protein Phosphatase 1 - metabolism; Proteins; Rats; Research and Analysis Methods; Rodents; Sarcoplasmic reticulum; Serine; Sex hormones; Signal transduction; Signal Transduction - drug effects; Signaling; Stem cells; Thoracic surgery; Threonine; United States--US; China; Missouri; Taiwan