Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 2 Interacts with a Host Protein Complex Involved in Mitochondrial Biogenesis and Intracellular Signaling
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from...
Saved in:
| Published in | Journal of Virology Vol. 83; no. 19; pp. 10314 - 10318 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Washington, DC
American Society for Microbiology
01.10.2009
American Society for Microbiology (ASM) |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0022-538X 1098-5514 1098-5514 |
| DOI | 10.1128/JVI.00842-09 |
Cover
| Abstract | Article Usage Stats
Services
JVI
Citing Articles
Google Scholar
PubMed
Related Content
Social Bookmarking
CiteULike
Delicious
Digg
Facebook
Google+
Mendeley
Reddit
StumbleUpon
Twitter
current issue
Spotlights in the Current Issue
JVI
About
JVI
Subscribers
Authors
Reviewers
Advertisers
Inquiries from the Press
Permissions & Commercial Reprints
ASM Journals Public Access Policy
JVI
RSS Feeds
1752 N Street N.W. • Washington DC 20036
202.737.3600 • 202.942.9355 fax • journals@asmusa.org
Print ISSN:
0022-538X
Online ISSN:
1098-5514
Copyright © 2014
by the
American Society for Microbiology.
For an alternate route to
JVI
.asm.org, visit:
JVI
|
|---|---|
| AbstractList | The severe acute respiratory syndrome coronavirus (SARS-CoV) generates 16 nonstructural proteins (nsp's) through proteolytic cleavage of a large precursor protein. Although several nsp's exhibit catalytic activities that are important for viral replication and transcription, other nsp's have less clearly defined roles during an infection. In order to gain a better understanding of their functions, we attempted to identify host proteins that interact with nsp's during SARS-CoV infections. For nsp2, we identified an interaction with two host proteins, prohibitin 1 (PHB1) and PHB2. Our results suggest that nsp2 may be involved in the disruption of intracellular host signaling during SARS-CoV infections.The severe acute respiratory syndrome coronavirus (SARS-CoV) generates 16 nonstructural proteins (nsp's) through proteolytic cleavage of a large precursor protein. Although several nsp's exhibit catalytic activities that are important for viral replication and transcription, other nsp's have less clearly defined roles during an infection. In order to gain a better understanding of their functions, we attempted to identify host proteins that interact with nsp's during SARS-CoV infections. For nsp2, we identified an interaction with two host proteins, prohibitin 1 (PHB1) and PHB2. Our results suggest that nsp2 may be involved in the disruption of intracellular host signaling during SARS-CoV infections. The severe acute respiratory syndrome coronavirus (SARS-CoV) generates 16 nonstructural proteins (nsp's) through proteolytic cleavage of a large precursor protein. Although several nsp's exhibit catalytic activities that are important for viral replication and transcription, other nsp's have less clearly defined roles during an infection. In order to gain a better understanding of their functions, we attempted to identify host proteins that interact with nsp's during SARS-CoV infections. For nsp2, we identified an interaction with two host proteins, prohibitin 1 (PHB1) and PHB2. Our results suggest that nsp2 may be involved in the disruption of intracellular host signaling during SARS-CoV infections. Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology. For an alternate route to JVI .asm.org, visit: JVI |
| Author | John R. Yates III Lujian Liao Michael J. Buchmeier Cromwell T. Cornillez-Ty Peter Kuhn |
| AuthorAffiliation | Molecular and Integrative Neurosciences Department, 1 Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, 2 Department of Molecular Biology and Biochemistry, 3 Division of Infectious Disease, Department of Medicine, University of California, Irvine, 3205 McGaugh Hall, Irvine, California 92697-3900 4 |
| AuthorAffiliation_xml | – name: Molecular and Integrative Neurosciences Department, 1 Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, 2 Department of Molecular Biology and Biochemistry, 3 Division of Infectious Disease, Department of Medicine, University of California, Irvine, 3205 McGaugh Hall, Irvine, California 92697-3900 4 |
| Author_xml | – sequence: 1 givenname: Cromwell T. surname: Cornillez-Ty fullname: Cornillez-Ty, Cromwell T. organization: Molecular and Integrative Neurosciences Department, Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037 – sequence: 2 givenname: Lujian surname: Liao fullname: Liao, Lujian organization: Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037 – sequence: 3 givenname: John R. surname: Yates fullname: Yates, John R. organization: Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037 – sequence: 4 givenname: Peter surname: Kuhn fullname: Kuhn, Peter organization: Department of Cell Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037 – sequence: 5 givenname: Michael J. surname: Buchmeier fullname: Buchmeier, Michael J. organization: Molecular and Integrative Neurosciences Department, Department of Molecular Biology and Biochemistry, Division of Infectious Disease, Department of Medicine, University of California, Irvine, 3205 McGaugh Hall, Irvine, California 92697-3900 |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21955760$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/19640993$$D View this record in MEDLINE/PubMed |
| BookMark | eNptkl9v0zAUxSM0xLrBG8_IEoInMmzHTpyXSaPaWNH4IwqIN8txb1pPiV1sJ6PfiQ-JS0sFiCdLvr97zrn2PcmOrLOQZY8JPiOEipdvvszOMBaM5ri-l00IrkXOOWFH2QRjSnNeiK_H2UkItxgTxkr2IDsmdclwXReT7MccRvCALvQQAX2EsDZeRec3aL6xC-96QFPnnVWj8UNA75wN0Q86Dl516IN3EYxFFM1sBK90DOjOxBVS6NqFeKhPXb_u4HuiRteNsEDp7q2JTq9c8jBJ6ZVxS7AQTEDKLrZySQ26buiUR3OztKozdvkwu9-qLsCj_Xmafb66_DS9zm_ev55NL25yzRiOeUsJp6xtW2iEaEoQvEkPQuqmFrgsCOesXVBGWq6hLaui4A2QFipNCGtIg4viNDvf6a6HpoeFhm2cTq696ZXfSKeM_LtizUou3ShpxQSmLAk83wt4922AEGVvwnYeZcENQZZVWQjCqwQ--dPpYPH7gxLwbA-ooFXXemW1CQeOkprzqsSJoztOexeCh1ZqE1U0bhvQdJJgud0WmbZF_toWievU9OKfpoP___GnO3xllqs740Gq0Mvb0UhRpMSpqSCs-Ak8vNC6 |
| CitedBy_id | crossref_primary_10_1002_iub_1366 crossref_primary_10_1002_jobm_202000537 crossref_primary_10_1016_j_bbagen_2020_129839 crossref_primary_10_3390_molecules27092723 crossref_primary_10_1128_JVI_00763_17 crossref_primary_10_1089_ars_2022_0126 crossref_primary_10_1089_dna_2020_5703 crossref_primary_10_1002_jmv_27009 crossref_primary_10_1099_jgv_0_001334 crossref_primary_10_1016_j_isci_2022_104646 crossref_primary_10_3390_jcm11195571 crossref_primary_10_3389_fviro_2022_918806 crossref_primary_10_1016_j_virusres_2024_199392 crossref_primary_10_3390_ph15070783 crossref_primary_10_1002_slct_202001709 crossref_primary_10_1016_j_scr_2021_102436 crossref_primary_10_3390_ijms241310818 crossref_primary_10_22207_JPAM_15_2_52 crossref_primary_10_1016_j_chembiol_2013_02_006 crossref_primary_10_1155_2021_5553173 crossref_primary_10_3390_ijms23073711 crossref_primary_10_1016_j_celrep_2021_109482 crossref_primary_10_1002_open_202000332 crossref_primary_10_1016_j_freeradbiomed_2020_09_027 crossref_primary_10_1080_14737159_2022_2015330 crossref_primary_10_3390_foods12183470 crossref_primary_10_1016_j_ijbiomac_2021_10_172 crossref_primary_10_1186_s12964_023_01104_5 crossref_primary_10_1186_s12967_020_02480_z crossref_primary_10_2217_fvl_2020_0124 crossref_primary_10_1016_j_tim_2020_12_007 crossref_primary_10_1016_j_virol_2022_03_005 crossref_primary_10_1007_s00705_023_05818_2 crossref_primary_10_1073_pnas_2204539119 crossref_primary_10_3390_v16050757 crossref_primary_10_7717_peerj_10609 crossref_primary_10_1590_1678_4685_gmb_2020_0212 crossref_primary_10_1007_s12250_015_3711_3 crossref_primary_10_1590_1678_4685_gmb_2020_0452 crossref_primary_10_3390_ijms22020532 crossref_primary_10_1016_j_meegid_2020_104474 crossref_primary_10_33073_pjm_2022_022 crossref_primary_10_1016_j_compbiomed_2020_104166 crossref_primary_10_21307_PM_2020_59_3_14 crossref_primary_10_3390_life10080152 crossref_primary_10_1371_journal_pone_0267847 crossref_primary_10_3390_cells10040821 crossref_primary_10_1016_j_virusres_2013_12_004 crossref_primary_10_3390_ijms22084260 crossref_primary_10_3390_ijms25042428 crossref_primary_10_1007_s11010_022_04393_5 crossref_primary_10_3389_fmolb_2020_605236 crossref_primary_10_1002_cbf_3766 crossref_primary_10_3390_cimb45120638 crossref_primary_10_3390_v14112436 crossref_primary_10_1186_s12985_021_01633_w crossref_primary_10_1128_JVI_01565_17 crossref_primary_10_1016_j_meegid_2021_104800 crossref_primary_10_1038_s41392_022_00884_5 crossref_primary_10_1016_j_cll_2022_02_005 crossref_primary_10_1128_JVI_00496_21 crossref_primary_10_1007_s12264_023_01110_0 crossref_primary_10_1007_s00249_021_01575_9 crossref_primary_10_1007_s10930_020_09901_4 crossref_primary_10_3389_fphys_2024_1406635 crossref_primary_10_1128_JVI_00197_15 crossref_primary_10_12688_f1000research_72896_1 crossref_primary_10_1111_cei_13523 crossref_primary_10_1038_s41586_021_03493_4 crossref_primary_10_1371_journal_pone_0088758 crossref_primary_10_1371_journal_pone_0246150 crossref_primary_10_3389_fviro_2024_1405680 crossref_primary_10_3390_ijms241613002 crossref_primary_10_1021_acs_analchem_3c05225 crossref_primary_10_1016_j_cellsig_2011_06_005 crossref_primary_10_3390_v16010156 crossref_primary_10_1590_1678_9199_jvatitd_2020_0183 crossref_primary_10_31083_j_fbl2702065 crossref_primary_10_1371_journal_ppat_1008100 crossref_primary_10_2174_0929867329666221004104430 crossref_primary_10_1016_j_mcp_2024_101973 crossref_primary_10_1038_s41467_021_24007_w crossref_primary_10_3389_fcimb_2020_575404 crossref_primary_10_1093_nar_gkaa1116 crossref_primary_10_3390_v16081331 crossref_primary_10_1007_s12250_021_00431_6 crossref_primary_10_1111_1348_0421_12230 crossref_primary_10_7554_eLife_69314 crossref_primary_10_1128_mbio_03368_23 crossref_primary_10_1128_CMR_00102_14 crossref_primary_10_1128_jvi_00555_23 crossref_primary_10_1016_j_ejmech_2020_112653 crossref_primary_10_3390_microorganisms8060850 crossref_primary_10_3389_fmolb_2021_653148 crossref_primary_10_1016_j_scs_2020_102466 crossref_primary_10_1021_acsinfecdis_0c00500 crossref_primary_10_2174_1568026623666230327125918 crossref_primary_10_1016_j_mito_2023_01_005 crossref_primary_10_3390_v15030611 crossref_primary_10_3390_vetsci11110531 crossref_primary_10_1016_j_fsi_2023_108689 crossref_primary_10_1002_ddr_21710 crossref_primary_10_1016_j_coviro_2017_01_002 crossref_primary_10_1016_j_arcmed_2022_08_006 crossref_primary_10_3389_fmicb_2021_612432 crossref_primary_10_1016_j_heliyon_2020_e05001 crossref_primary_10_1016_j_ijbiomac_2024_134850 crossref_primary_10_1093_mtomcs_mfac047 crossref_primary_10_1134_S0026893322010022 crossref_primary_10_1371_journal_ppat_1005501 crossref_primary_10_1016_j_compbiomed_2022_105575 crossref_primary_10_3389_fmicb_2022_907422 crossref_primary_10_1016_j_bbrep_2020_100847 crossref_primary_10_3390_ijms23126394 crossref_primary_10_3390_pathogens11121555 crossref_primary_10_3390_ijms231810716 crossref_primary_10_1016_j_jbc_2024_105632 crossref_primary_10_1016_j_prmcm_2023_100320 crossref_primary_10_3389_fphar_2021_616993 crossref_primary_10_1128_mBio_00524_13 crossref_primary_10_1016_j_jiph_2021_08_014 crossref_primary_10_7717_peerj_11171 crossref_primary_10_1038_s41598_022_13373_0 crossref_primary_10_1186_s12985_023_02021_2 crossref_primary_10_1146_annurev_biochem_052521_115653 crossref_primary_10_1038_s42003_021_01754_6 crossref_primary_10_1016_j_virol_2020_12_010 crossref_primary_10_1016_j_jiph_2021_05_009 crossref_primary_10_1038_s41588_022_01131_x crossref_primary_10_1016_j_micpath_2021_104809 crossref_primary_10_1016_j_isci_2020_101631 crossref_primary_10_1126_science_abm1208 crossref_primary_10_1074_mcp_M110_007443 crossref_primary_10_1111_febs_16275 crossref_primary_10_1128_JVI_00901_10 crossref_primary_10_1055_s_0041_1732782 crossref_primary_10_1016_j_biochi_2022_04_002 crossref_primary_10_1016_j_jchemneu_2023_102321 crossref_primary_10_3390_pathogens7040097 crossref_primary_10_1016_j_ijbiomac_2021_02_212 crossref_primary_10_15252_msb_202010079 crossref_primary_10_1152_ajpcell_00224_2020 crossref_primary_10_7717_peerj_10234 crossref_primary_10_1039_C5BM00113G crossref_primary_10_1016_j_biopha_2020_110493 crossref_primary_10_1073_pnas_2103554118 crossref_primary_10_1186_s43556_021_00060_1 crossref_primary_10_1080_07391102_2021_2017354 |
| Cites_doi | 10.1128/JVI.79.21.13399-13411.2005 10.1016/S0092-8674(03)00424-0 10.1056/NEJMoa030781 10.1371/journal.ppat.0030112 10.1128/JVI.00547-07 10.1073/pnas.0508200103 10.1056/NEJMoa030747 10.1128/JVI.01358-06 10.1128/JVI.00407-08 10.1128/JVI.02817-06 10.1016/j.molcel.2004.05.006 10.1073/pnas.1332608100 10.1242/jcs.01142 10.1074/jbc.M806061200 10.1371/journal.pbio.0060226 10.1126/science.1085953 10.1128/JVI.01296-07 10.1126/science.1085952 10.1056/NEJMoa030634 10.1038/sj.onc.1202684 10.1128/JVI.78.22.12218-12224.2004 10.1016/j.jmb.2006.06.021 10.1007/978-0-387-33012-9_8 10.1038/ncb1283 10.1016/j.bbamcr.2008.05.013 10.1074/jbc.M305171200 10.1073/pnas.0601708103 10.1099/vir.0.19424-0 10.1128/MCB.26.3.871-882.2006 10.1128/JVI.78.11.5619-5632.2004 10.1016/j.virol.2005.02.017 10.1128/JVI.02472-07 10.1038/85686 10.1074/jbc.M708375200 10.1128/JVI.79.10.6180-6193.2005 |
| ContentType | Journal Article |
| Copyright | 2009 INIST-CNRS Copyright © 2009, American Society for Microbiology |
| Copyright_xml | – notice: 2009 INIST-CNRS – notice: Copyright © 2009, American Society for Microbiology |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 7X8 5PM |
| DOI | 10.1128/JVI.00842-09 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic CrossRef MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1098-5514 |
| EndPage | 10318 |
| ExternalDocumentID | PMC2748024 19640993 21955760 10_1128_JVI_00842_09 jvi_83_19_10314 |
| Genre | Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NIAID NIH HHS grantid: T32 AI007354 – fundername: NIAID NIH HHS grantid: AI059799 – fundername: NINDS NIH HHS grantid: P30 NS057096 – fundername: NIAID NIH HHS grantid: T32 AI-07354 – fundername: NINDS NIH HHS grantid: P30NS057096 – fundername: NIAID NIH HHS grantid: R01 AI059799 – fundername: NCRR NIH HHS grantid: P41 RR011823 – fundername: PHS HHS grantid: HHSN266200400058C |
| GroupedDBID | --- -~X .55 .GJ 0R~ 18M 29L 2WC 39C 3O- 4.4 41~ 53G 5GY 5RE 5VS 6TJ 85S AAFWJ AAGFI AAYJJ AAYXX ABPPZ ACGFO ACNCT ADBBV ADXHL AENEX AFFNX AGVNZ AI. ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BTFSW C1A CITATION CS3 D0S DIK E3Z EBS EJD F5P FRP GX1 H13 HYE HZ~ IH2 KQ8 MVM N9A O9- OHT OK1 P2P RHI RNS RPM RSF TR2 UPT VH1 W2D W8F WH7 WOQ X7M Y6R YQT ZGI ZXP ~02 ~KM IQODW CGR CUY CVF ECM EIF NPM 7X8 5PM |
| ID | FETCH-LOGICAL-c440t-f21524fffeb88b6e85b55119b980631554fd241f5cef67335be1fe7c114b1b033 |
| ISSN | 0022-538X 1098-5514 |
| IngestDate | Thu Aug 21 13:56:45 EDT 2025 Thu Sep 04 21:41:05 EDT 2025 Thu Apr 03 07:10:07 EDT 2025 Mon Jul 21 09:15:34 EDT 2025 Tue Jul 01 00:57:37 EDT 2025 Thu Apr 24 23:08:11 EDT 2025 Wed May 18 15:25:41 EDT 2016 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 19 |
| Keywords | Infection Virus Lung disease Mitochondria Coronavirus Respiratory disease Viral disease Severe acute respiratory syndrome Intracellular Coronaviridae Nidovirales Protein |
| Language | English |
| License | CC BY 4.0 |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c440t-f21524fffeb88b6e85b55119b980631554fd241f5cef67335be1fe7c114b1b033 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Corresponding author. Mailing address: Department of Molecular Biology and Biochemistry and Division of Infectious Disease, Department of Medicine, University of California, Irvine, 3205 McGaugh Hall, Irvine, CA 92697-3900. Phone: (949) 824-5781. Fax: (949) 824-9437. E-mail: m.buchmeier@uci.edu |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/2748024 |
| PMID | 19640993 |
| PQID | 67638157 |
| PQPubID | 23479 |
| PageCount | 5 |
| ParticipantIDs | pubmed_primary_19640993 pubmedcentral_primary_oai_pubmedcentral_nih_gov_2748024 pascalfrancis_primary_21955760 crossref_primary_10_1128_JVI_00842_09 crossref_citationtrail_10_1128_JVI_00842_09 proquest_miscellaneous_67638157 highwire_asm_jvi_83_19_10314 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2009-10-01 |
| PublicationDateYYYYMMDD | 2009-10-01 |
| PublicationDate_xml | – month: 10 year: 2009 text: 2009-10-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | Washington, DC |
| PublicationPlace_xml | – name: Washington, DC – name: United States |
| PublicationTitle | Journal of Virology |
| PublicationTitleAlternate | J Virol |
| PublicationYear | 2009 |
| Publisher | American Society for Microbiology American Society for Microbiology (ASM) |
| Publisher_xml | – name: American Society for Microbiology – name: American Society for Microbiology (ASM) |
| References | e_1_3_2_26_2 e_1_3_2_27_2 e_1_3_2_28_2 e_1_3_2_29_2 e_1_3_2_20_2 e_1_3_2_21_2 e_1_3_2_22_2 e_1_3_2_23_2 e_1_3_2_24_2 e_1_3_2_25_2 e_1_3_2_9_2 e_1_3_2_15_2 e_1_3_2_8_2 e_1_3_2_16_2 e_1_3_2_37_2 e_1_3_2_7_2 e_1_3_2_17_2 e_1_3_2_6_2 e_1_3_2_18_2 e_1_3_2_19_2 e_1_3_2_30_2 e_1_3_2_32_2 e_1_3_2_10_2 e_1_3_2_31_2 e_1_3_2_11_2 e_1_3_2_34_2 e_1_3_2_4_2 e_1_3_2_12_2 e_1_3_2_33_2 e_1_3_2_3_2 e_1_3_2_13_2 e_1_3_2_36_2 e_1_3_2_2_2 e_1_3_2_14_2 e_1_3_2_35_2 (e_1_3_2_5_2) 2007; 40 18417574 - J Virol. 2008 Aug;82(16):8071-84 18809673 - J Biol Chem. 2008 Nov 21;283(47):32254-63 17696609 - PLoS Pathog. 2007 Aug 10;3(8):e112 11231557 - Nat Biotechnol. 2001 Mar;19(3):242-7 15175163 - Mol Cell. 2004 Jun 4;14(5):685-91 12809601 - Cell. 2003 Jun 13;113(6):701-2 15140959 - J Virol. 2004 Jun;78(11):5619-32 18558096 - Biochim Biophys Acta. 2009 Jan;1793(1):27-32 15173318 - J Cell Sci. 2004 Jun 15;117(Pt 14):3021-9 17804504 - J Virol. 2007 Nov;81(22):12135-44 12917450 - J Gen Virol. 2003 Sep;84(Pt 9):2305-15 16041367 - Nat Cell Biol. 2005 Aug;7(8):837-43 12690092 - N Engl J Med. 2003 May 15;348(20):1953-66 15840516 - Virology. 2005 May 10;335(2):165-76 12730500 - Science. 2003 May 30;300(5624):1394-9 12671061 - N Engl J Med. 2003 May 15;348(20):1995-2005 14500729 - J Biol Chem. 2003 Nov 28;278(48):47853-61 16227261 - J Virol. 2005 Nov;79(21):13399-411 17927896 - J Biochem Mol Biol. 2007 Sep 30;40(5):649-55 12690091 - N Engl J Med. 2003 May 15;348(20):1967-76 18798692 - PLoS Biol. 2008 Sep 16;6(9):e226 17037504 - Adv Exp Med Biol. 2006;581:55-60 16882730 - Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11892-7 16828802 - J Mol Biol. 2006 Aug 11;361(2):243-56 16928755 - J Virol. 2007 Jan;81(1):20-9 17898055 - J Virol. 2007 Dec;81(24):13587-97 12802011 - Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7480-5 18305050 - J Virol. 2008 May;82(9):4471-9 12730501 - Science. 2003 May 30;300(5624):1399-404 18045871 - J Biol Chem. 2008 Feb 8;283(6):3655-64 15507608 - J Virol. 2004 Nov;78(22):12218-24 16549795 - Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5108-13 17409150 - J Virol. 2007 Jun;81(12):6700-8 16428443 - Mol Cell Biol. 2006 Feb;26(3):871-82 10376528 - Oncogene. 1999 Jun 10;18(23):3501-10 15858003 - J Virol. 2005 May;79(10):6180-93 |
| References_xml | – ident: e_1_3_2_14_2 doi: 10.1128/JVI.79.21.13399-13411.2005 – ident: e_1_3_2_35_2 doi: 10.1016/S0092-8674(03)00424-0 – ident: e_1_3_2_21_2 doi: 10.1056/NEJMoa030781 – ident: e_1_3_2_9_2 doi: 10.1371/journal.ppat.0030112 – ident: e_1_3_2_19_2 doi: 10.1128/JVI.00547-07 – volume: 40 start-page: 649 year: 2007 ident: e_1_3_2_5_2 publication-title: J. Biochem. Mol. Biol. – ident: e_1_3_2_24_2 doi: 10.1073/pnas.0508200103 – ident: e_1_3_2_10_2 doi: 10.1056/NEJMoa030747 – ident: e_1_3_2_31_2 doi: 10.1128/JVI.01358-06 – ident: e_1_3_2_8_2 doi: 10.1128/JVI.00407-08 – ident: e_1_3_2_17_2 doi: 10.1128/JVI.02817-06 – ident: e_1_3_2_30_2 doi: 10.1016/j.molcel.2004.05.006 – ident: e_1_3_2_7_2 doi: 10.1073/pnas.1332608100 – ident: e_1_3_2_32_2 doi: 10.1242/jcs.01142 – ident: e_1_3_2_18_2 doi: 10.1074/jbc.M806061200 – ident: e_1_3_2_20_2 doi: 10.1371/journal.pbio.0060226 – ident: e_1_3_2_22_2 doi: 10.1126/science.1085953 – ident: e_1_3_2_12_2 doi: 10.1128/JVI.01296-07 – ident: e_1_3_2_29_2 doi: 10.1126/science.1085952 – ident: e_1_3_2_26_2 doi: 10.1056/NEJMoa030634 – ident: e_1_3_2_36_2 doi: 10.1038/sj.onc.1202684 – ident: e_1_3_2_2_2 doi: 10.1128/JVI.78.22.12218-12224.2004 – ident: e_1_3_2_4_2 doi: 10.1016/j.jmb.2006.06.021 – ident: e_1_3_2_11_2 doi: 10.1007/978-0-387-33012-9_8 – ident: e_1_3_2_27_2 doi: 10.1038/ncb1283 – ident: e_1_3_2_23_2 doi: 10.1016/j.bbamcr.2008.05.013 – ident: e_1_3_2_13_2 doi: 10.1074/jbc.M305171200 – ident: e_1_3_2_28_2 doi: 10.1073/pnas.0601708103 – ident: e_1_3_2_34_2 doi: 10.1099/vir.0.19424-0 – ident: e_1_3_2_15_2 doi: 10.1128/MCB.26.3.871-882.2006 – ident: e_1_3_2_16_2 doi: 10.1128/JVI.78.11.5619-5632.2004 – ident: e_1_3_2_6_2 doi: 10.1016/j.virol.2005.02.017 – ident: e_1_3_2_25_2 doi: 10.1128/JVI.02472-07 – ident: e_1_3_2_37_2 doi: 10.1038/85686 – ident: e_1_3_2_3_2 doi: 10.1074/jbc.M708375200 – ident: e_1_3_2_33_2 doi: 10.1128/JVI.79.10.6180-6193.2005 – reference: 15140959 - J Virol. 2004 Jun;78(11):5619-32 – reference: 12809601 - Cell. 2003 Jun 13;113(6):701-2 – reference: 15175163 - Mol Cell. 2004 Jun 4;14(5):685-91 – reference: 15507608 - J Virol. 2004 Nov;78(22):12218-24 – reference: 18417574 - J Virol. 2008 Aug;82(16):8071-84 – reference: 16882730 - Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11892-7 – reference: 11231557 - Nat Biotechnol. 2001 Mar;19(3):242-7 – reference: 17409150 - J Virol. 2007 Jun;81(12):6700-8 – reference: 18558096 - Biochim Biophys Acta. 2009 Jan;1793(1):27-32 – reference: 17037504 - Adv Exp Med Biol. 2006;581:55-60 – reference: 15858003 - J Virol. 2005 May;79(10):6180-93 – reference: 17696609 - PLoS Pathog. 2007 Aug 10;3(8):e112 – reference: 12690092 - N Engl J Med. 2003 May 15;348(20):1953-66 – reference: 15840516 - Virology. 2005 May 10;335(2):165-76 – reference: 16549795 - Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5108-13 – reference: 12917450 - J Gen Virol. 2003 Sep;84(Pt 9):2305-15 – reference: 17898055 - J Virol. 2007 Dec;81(24):13587-97 – reference: 12730500 - Science. 2003 May 30;300(5624):1394-9 – reference: 15173318 - J Cell Sci. 2004 Jun 15;117(Pt 14):3021-9 – reference: 10376528 - Oncogene. 1999 Jun 10;18(23):3501-10 – reference: 12690091 - N Engl J Med. 2003 May 15;348(20):1967-76 – reference: 12730501 - Science. 2003 May 30;300(5624):1399-404 – reference: 14500729 - J Biol Chem. 2003 Nov 28;278(48):47853-61 – reference: 16428443 - Mol Cell Biol. 2006 Feb;26(3):871-82 – reference: 18809673 - J Biol Chem. 2008 Nov 21;283(47):32254-63 – reference: 16041367 - Nat Cell Biol. 2005 Aug;7(8):837-43 – reference: 12671061 - N Engl J Med. 2003 May 15;348(20):1995-2005 – reference: 18798692 - PLoS Biol. 2008 Sep 16;6(9):e226 – reference: 17804504 - J Virol. 2007 Nov;81(22):12135-44 – reference: 16227261 - J Virol. 2005 Nov;79(21):13399-411 – reference: 18305050 - J Virol. 2008 May;82(9):4471-9 – reference: 16928755 - J Virol. 2007 Jan;81(1):20-9 – reference: 17927896 - J Biochem Mol Biol. 2007 Sep 30;40(5):649-55 – reference: 18045871 - J Biol Chem. 2008 Feb 8;283(6):3655-64 – reference: 16828802 - J Mol Biol. 2006 Aug 11;361(2):243-56 – reference: 12802011 - Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7480-5 |
| SSID | ssj0014464 |
| Score | 2.3975117 |
| Snippet | Article Usage Stats
Services
JVI
Citing Articles
Google Scholar
PubMed
Related Content
Social Bookmarking
CiteULike
Delicious
Digg
Facebook
Google+
Mendeley... The severe acute respiratory syndrome coronavirus (SARS-CoV) generates 16 nonstructural proteins (nsp's) through proteolytic cleavage of a large precursor... |
| SourceID | pubmedcentral proquest pubmed pascalfrancis crossref highwire |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 10314 |
| SubjectTerms | Amino Acid Sequence Biological and medical sciences Blotting, Western Catalysis Cell Line Fundamental and applied biological sciences. Psychology Humans Microbiology Miscellaneous Mitochondria - metabolism Molecular Sequence Data Protein Binding Protein Structure, Tertiary Repressor Proteins - chemistry SARS Virus - metabolism Signal Transduction Transcription, Genetic Viral Nonstructural Proteins - genetics Viral Nonstructural Proteins - metabolism Virology Virus-Cell Interactions |
| Title | Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 2 Interacts with a Host Protein Complex Involved in Mitochondrial Biogenesis and Intracellular Signaling |
| URI | http://jvi.asm.org/content/83/19/10314.abstract https://www.ncbi.nlm.nih.gov/pubmed/19640993 https://www.proquest.com/docview/67638157 https://pubmed.ncbi.nlm.nih.gov/PMC2748024 |
| Volume | 83 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Jb9QwFLaGIiQuiJ1AKT7AaRTI4mxHVLWUMpQDM2g4WbFj01TpDOosgv4jJH4k7zlxJoFBLJcoSixneZ_tZ_t73yPkaSClH0vJ3DBkgcuCIsRNQmh4sSfiSEaaMYwdfnsSH03Y8TSaDgbfOqyl1VI8l5db40r-x6pwDeyKUbL_YNm2UrgA52BfOIKF4fhXNn6v4JVRDwM3-y86m-ZWh2AoUaAgX5cXqMM6b9RijdKGEWgoZ8PAKEZgrJQNdBti4Ed733DO1RcoBR3ZWqFU0_AcugHoNuEZuN4uyvkn7DHLRSPltITaVFUZgivyQ_LKjo-_esEYZtdd2N_HOLGqUpfuuKYFw2eY9cWWzD0qc7O8O1qddaD9EX1myy3esCDfrE5nfRqyXeHIWq6c7ZRR8xQ9u3rM2nKt6cnrlDgWsVmnX8ZkFmz7iBFgFMTxh9codAtw9bLNyGjZACfv-OFkNOLjg-n4CrkaJImP7NFX05ZNhLNqQ2Cwr2VjLIL0RbfuvvdjFamRkJsvoE3qOpnKttnOz6Tdjhc0vkluNIajL2ss3iIDNbtNrtUJTb_eId9rRFKDSNpBJLWIpB1E0h4iaYM4GtAWkRQRSXOKiGzvN4ikFpFwQnuIpBtEUkAk7SGStoi8SyaHB-P9I7fJB-JKxrylqzEHM9NaK5GmIlZpJCLcBhdZCo42Osa6AIdUR1LpOAnDSChfq0TClF_4wgvDe2QHPkw9IFRleREleVrEgWRFrEUhmYdR3iIReaBzhwytnbhsxPIxZ0vFzaQ5SDlYlRurci9zyLO29OdaJOY35XatyXm-OOdn65KnIfczbvDpkL0eDNq6wKuIoiT2HPLE4oLDKIA_Lp-p-WrBY3ATUj9KHHK_RsnmPbKYwSwwdEjSw09bAPXl-3dm5anRmQ8SloIL__CPT31Erm_a7S7ZAeSox-CrL8WeaSU_AAf7-LI |
| linkProvider | Geneva Foundation for Medical Education and Research |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Severe+acute+respiratory+syndrome+coronavirus+nonstructural+protein+2+interacts+with+a+host+protein+complex+involved+in+mitochondrial+biogenesis+and+intracellular+signaling&rft.jtitle=Journal+of+virology&rft.au=Cornillez-Ty%2C+Cromwell+T&rft.au=Liao%2C+Lujian&rft.au=Yates%2C+John+R&rft.au=Kuhn%2C+Peter&rft.date=2009-10-01&rft.issn=1098-5514&rft.eissn=1098-5514&rft.volume=83&rft.issue=19&rft.spage=10314&rft_id=info:doi/10.1128%2FJVI.00842-09&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-538X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-538X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-538X&client=summon |