An Improved PID Algorithm Based on Insulin-on-Board Estimate for Blood Glucose Control with Type 1 Diabetes
Automated closed-loop insulin infusion therapy has been studied for many years. In closed-loop system, the control algorithm is the key technique of precise insulin infusion. The control algorithm needs to be designed and validated. In this paper, an improved PID algorithm based on insulin-on-board...
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| Published in | Computational and mathematical methods in medicine Vol. 2015; no. 2015; pp. 1 - 8 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Cairo, Egypt
Hindawi Publishing Corporation
01.01.2015
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1748-670X 1748-6718 1748-6718 |
| DOI | 10.1155/2015/281589 |
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| Abstract | Automated closed-loop insulin infusion therapy has been studied for many years. In closed-loop system, the control algorithm is the key technique of precise insulin infusion. The control algorithm needs to be designed and validated. In this paper, an improved PID algorithm based on insulin-on-board estimate is proposed and computer simulations are done using a combinational mathematical model of the dynamics of blood glucose-insulin regulation in the blood system. The simulation results demonstrate that the improved PID algorithm can perform well in different carbohydrate ingestion and different insulin sensitivity situations. Compared with the traditional PID algorithm, the control performance is improved obviously and hypoglycemia can be avoided. To verify the effectiveness of the proposed control algorithm, in silico testing is done using the UVa/Padova virtual patient software. |
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| AbstractList | Automated closed-loop insulin infusion therapy has been studied for many years. In closed-loop system, the control algorithm is the key technique of precise insulin infusion. The control algorithm needs to be designed and validated. In this paper, an improved PID algorithm based on insulin-on-board estimate is proposed and computer simulations are done using a combinational mathematical model of the dynamics of blood glucose-insulin regulation in the blood system. The simulation results demonstrate that the improved PID algorithm can perform well in different carbohydrate ingestion and different insulin sensitivity situations. Compared with the traditional PID algorithm, the control performance is improved obviously and hypoglycemia can be avoided. To verify the effectiveness of the proposed control algorithm, in silico testing is done using the UVa/Padova virtual patient software. Automated closed-loop insulin infusion therapy has been studied for many years. In closed-loop system, the control algorithm is the key technique of precise insulin infusion. The control algorithm needs to be designed and validated. In this paper, an improved PID algorithm based on insulin-on-board estimate is proposed and computer simulations are done using a combinational mathematical model of the dynamics of blood glucose-insulin regulation in the blood system. The simulation results demonstrate that the improved PID algorithm can perform well in different carbohydrate ingestion and different insulin sensitivity situations. Compared with the traditional PID algorithm, the control performance is improved obviously and hypoglycemia can be avoided. To verify the effectiveness of the proposed control algorithm, in silico testing is done using the UVa/Padova virtual patient software.Automated closed-loop insulin infusion therapy has been studied for many years. In closed-loop system, the control algorithm is the key technique of precise insulin infusion. The control algorithm needs to be designed and validated. In this paper, an improved PID algorithm based on insulin-on-board estimate is proposed and computer simulations are done using a combinational mathematical model of the dynamics of blood glucose-insulin regulation in the blood system. The simulation results demonstrate that the improved PID algorithm can perform well in different carbohydrate ingestion and different insulin sensitivity situations. Compared with the traditional PID algorithm, the control performance is improved obviously and hypoglycemia can be avoided. To verify the effectiveness of the proposed control algorithm, in silico testing is done using the UVa/Padova virtual patient software. Automated closed-loop insulin infusion therapy has been studied for many years. In closed-loop system, the control algorithm is the key technique of precise insulin infusion. The control algorithm needs to be designed and validated. In this paper, an improved PID algorithm based on insulin-on-board estimate is proposed and computer simulations are done using a combinational mathematical model of the dynamics of blood glucose-insulin regulation in the blood system. The simulation results demonstrate that the improved PID algorithm can perform well in different carbohydrate ingestion and different insulin sensitivity situations. Compared with the traditional PID algorithm, the control performance is improved obviously and hypoglycemia can be avoided. To verify the effectiveness of the proposed control algorithm, in silico testing is done using the UVa/Padova virtual patient software. |
| Author | Hu, Ruiqiang Li, Chengwei |
| AuthorAffiliation | School of Electrical Engineering and Automation, Harbin Institute of Technology, Harbin 150001, China |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26550021$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.bspc.2009.03.002 10.1016/j.conengprac.2012.11.015 10.1177/193229680900300319 10.1016/j.jtbi.2006.04.002 10.1089/dia.2007.0284 10.1016/j.cmpb.2010.08.013 10.1016/j.bspc.2013.06.008 10.1155/2013/712496 10.1016/j.conengprac.2014.02.012 10.1007/bf02442625 10.1016/j.amc.2008.06.030 10.1007/bf02477259 10.1109/tbme.2006.883792 10.1109/tbme.2008.915665 10.1088/0967-3334/25/4/010 10.1177/193229680800200414 10.1016/j.cmpb.2012.01.011 10.1016/j.bspc.2009.04.003 10.1089/dia.2005.7.849 10.1172/jci110398 |
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| Copyright | Copyright © 2015 Ruiqiang Hu and Chengwei Li. Copyright © 2015 R. Hu and C. Li. 2015 |
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| References | (16) 2006; 53 (10) 2013; 109 (19) 2013; 8 http://www.idf.org (8) 2009; 4 (15) 2004; 25 (4) 2008; 10 (3) 2008; 55 (9) 2009; 209 (12) 1965; 27 (18) 2009; 3 (17) 2013; 2013 (5) 2014; 28 (20) 2005; 7 (1) 2006; 242 (7) 2009; 4 (14) 1983; 21 (21) 2008; 2 (11) 2013; 21 (13) 1981; 68 (6) 2011; 102 11 12 13 14 15 16 17 18 19 1 3 4 5 6 7 8 9 20 10 21 19885239 - J Diabetes Sci Technol. 2008 Jul;2(4):630-5 15382830 - Physiol Meas. 2004 Aug;25(4):905-20 16386091 - Diabetes Technol Ther. 2005 Dec;7(6):849-62 21163548 - Comput Methods Programs Biomed. 2011 May;102(2):119-29 24260042 - Comput Math Methods Med. 2013;2013:712496 17153204 - IEEE Trans Biomed Eng. 2006 Dec;53(12 Pt 1):2472-8 18334377 - IEEE Trans Biomed Eng. 2008 Mar;55(3):857-65 6350741 - Med Biol Eng Comput. 1983 Jul;21(4):390-9 22424730 - Comput Methods Programs Biomed. 2013 Feb;109(2):144-56 5884133 - Bull Math Biophys. 1965;27:Suppl:21-37 19049372 - Diabetes Technol Ther. 2008 Dec;10(6):441-4 16712872 - J Theor Biol. 2006 Oct 7;242(3):722-35 20144293 - J Diabetes Sci Technol. 2009 May;3(3):536-44 7033284 - J Clin Invest. 1981 Dec;68(6):1456-67 |
| References_xml | – volume: 2013 year: 2013 end-page: 10 ident: 17 article-title: Systematically comparison of unihormonal and bihormonal artificial pancreas systems – volume: 102 start-page: 119 issue: 2 year: 2011 end-page: 129 ident: 6 article-title: A new general glucose homeostatic model using a proportional-integral-derivative controller – volume: 242 start-page: 722 issue: 3 year: 2006 end-page: 735 ident: 1 article-title: Modeling the glucose-insulin regulatory system and ultradian insulin secretory oscillations with two explicit time delays – volume: 10 start-page: 441 issue: 6 year: 2008 end-page: 444 ident: 4 article-title: Bolus calculator: a review of four ‘smart’ insulin pumps – volume: 7 start-page: 849 issue: 6 year: 2005 end-page: 862 ident: 20 article-title: Quantifying temporal glucose variability in diabetes via continuous glucose monitoring: mathematical methods and clinical application – volume: 27 start-page: 21 issue: 1 year: 1965 end-page: 37 ident: 12 article-title: Model studies of blood-glucose regulation – volume: 53 start-page: 2472 issue: 12 year: 2006 end-page: 2478 ident: 16 article-title: A system model of oral glucose absorption validation on gold standard data – volume: 3 start-page: 536 issue: 3 year: 2009 end-page: 544 ident: 18 article-title: Safety constraints in an artificial pancreatic cell: an implementation of model predictive control with insulin on board – volume: 68 start-page: 1456 issue: 6 year: 1981 end-page: 1467 ident: 13 article-title: Physiologic evaluation of factors controlling glucose tolerance in man. Measurement of insulin sensitivity and -cell glucose sensitivity from the response to intravenous glucose – volume: 21 start-page: 390 issue: 4 year: 1983 end-page: 399 ident: 14 article-title: Validation of mathematical models of complex endocrine-metabolic systems. A case study on a model of glucose regulation – volume: 25 start-page: 905 issue: 4 year: 2004 end-page: 920 ident: 15 article-title: Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes – volume: 109 start-page: 144 issue: 2 year: 2013 end-page: 156 ident: 10 article-title: Adaptive blood glucose control for intensive care applications – volume: 55 start-page: 857 issue: 3 year: 2008 end-page: 865 ident: 3 article-title: An improved PID switching control strategy for type 1 diabetes – volume: 4 start-page: 338 issue: 4 year: 2009 end-page: 346 ident: 8 article-title: Model predictive control of glucose concentration in type I diabetic patients: an in silico trial – reference: http://www.idf.org/ – volume: 28 start-page: 26 issue: 1 year: 2014 end-page: 33 ident: 5 article-title: Nonlinear glucose-insulin control considering delays-Part II: control algorithm – volume: 209 start-page: 19 issue: 1 year: 2009 end-page: 30 ident: 9 article-title: Glucose optimal control system in diabetes treatment – volume: 8 start-page: 724 issue: 6 year: 2013 end-page: 732 ident: 19 article-title: Postprandial blood glucose control using a hybrid adaptive PD controller with insulin-on-board limitation – volume: 4 start-page: 347 issue: 4 year: 2009 end-page: 354 ident: 7 article-title: A closed-loop artificial pancreas based on model predictive control: human-friendly identification and automatic meal disturbance rejection – volume: 21 start-page: 747 issue: 5 year: 2013 end-page: 758 ident: 11 article-title: High-order sliding-mode control for blood glucose: practical relative degree approach – volume: 2 start-page: 630 issue: 4 year: 2008 end-page: 635 ident: 21 article-title: Evaluating the efficacy of closed-loop glucose regulation via control-variability grid analysis – ident: 7 doi: 10.1016/j.bspc.2009.03.002 – ident: 11 doi: 10.1016/j.conengprac.2012.11.015 – ident: 18 doi: 10.1177/193229680900300319 – ident: 1 doi: 10.1016/j.jtbi.2006.04.002 – ident: 4 doi: 10.1089/dia.2007.0284 – ident: 6 doi: 10.1016/j.cmpb.2010.08.013 – ident: 19 doi: 10.1016/j.bspc.2013.06.008 – ident: 17 doi: 10.1155/2013/712496 – ident: 5 doi: 10.1016/j.conengprac.2014.02.012 – ident: 14 doi: 10.1007/bf02442625 – ident: 9 doi: 10.1016/j.amc.2008.06.030 – ident: 12 doi: 10.1007/bf02477259 – ident: 16 doi: 10.1109/tbme.2006.883792 – ident: 3 doi: 10.1109/tbme.2008.915665 – ident: 15 doi: 10.1088/0967-3334/25/4/010 – ident: 21 doi: 10.1177/193229680800200414 – ident: 10 doi: 10.1016/j.cmpb.2012.01.011 – ident: 8 doi: 10.1016/j.bspc.2009.04.003 – ident: 20 doi: 10.1089/dia.2005.7.849 – ident: 13 doi: 10.1172/jci110398 – reference: 15382830 - Physiol Meas. 2004 Aug;25(4):905-20 – reference: 16712872 - J Theor Biol. 2006 Oct 7;242(3):722-35 – reference: 19885239 - J Diabetes Sci Technol. 2008 Jul;2(4):630-5 – reference: 6350741 - Med Biol Eng Comput. 1983 Jul;21(4):390-9 – reference: 24260042 - Comput Math Methods Med. 2013;2013:712496 – reference: 5884133 - Bull Math Biophys. 1965;27:Suppl:21-37 – reference: 7033284 - J Clin Invest. 1981 Dec;68(6):1456-67 – reference: 17153204 - IEEE Trans Biomed Eng. 2006 Dec;53(12 Pt 1):2472-8 – reference: 18334377 - IEEE Trans Biomed Eng. 2008 Mar;55(3):857-65 – reference: 19049372 - Diabetes Technol Ther. 2008 Dec;10(6):441-4 – reference: 22424730 - Comput Methods Programs Biomed. 2013 Feb;109(2):144-56 – reference: 20144293 - J Diabetes Sci Technol. 2009 May;3(3):536-44 – reference: 21163548 - Comput Methods Programs Biomed. 2011 May;102(2):119-29 – reference: 16386091 - Diabetes Technol Ther. 2005 Dec;7(6):849-62 |
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| SubjectTerms | Algorithms Blood Glucose - metabolism Computational Biology Computer Simulation Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Humans Insulin - administration & dosage Insulin - blood Insulin - pharmacokinetics Insulin Infusion Systems - statistics & numerical data Mathematical Concepts Models, Biological User-Computer Interface |
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| Title | An Improved PID Algorithm Based on Insulin-on-Board Estimate for Blood Glucose Control with Type 1 Diabetes |
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