Minimization of CYP2D6 Polymorphic Differences and Improved Bioavailability via Transdermal Administration: Latrepirdine Example - Chew, Marci L.; Mordenti, Joyce; Yeoh, Thean; Ranade, Gautam; Qiu, Ruolun; Fang, Juanzhi; Liang, Yali; Corrigan, Brian (Pharmaceutical research, 2016)
Keywords: Administration, Cutaneous; Aged; Bioavailability; Biochemistry; Biological Availability; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Cross-Over Studies; Cytochrome P-450 CYP2D6 - metabolism; Female; Humans; Indoles - administration & dosage; Indoles - pharmacokinetics; Kinetics; Male; Medical Law; Middle Aged; Pharmacology; Pharmacology/Toxicology; Pharmacy; Physiological aspects; Pilot Projects; Polymorphism; Research Paper; Transdermal medication; pharmacokinetics; bioavailability; CYP2D6; transdermal; latrepirdine