A Shift Algorithm for Exact Computation in Sequential Tests with Binary Outcome - failures, A simple shift algorithm is described enabling the exact determination of power functions; analyses, but the number of interim; times, the monitoring; examples, the continuation regions may be specified as desired To give; (CYTEL, exact properties of designs proposed by the program package East; determined, ) are; far, plans with interim analyses are considered where decisions are based on the conditional power (Biometrical journal, 2000)
Keywords: Binary outcome variable; Exact computation; Group sequential plans; Sequential Tests; Shift Algorithm; Two-sample comparison