Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen - Oliver, David; Ji, Hao; Liu, Piaomu; Gasparian, Alexander; Gardiner, Ellen; Lee, Samuel; Zenteno, Adrian; Perinskaya, Lillian O.; Chen, Mengqian; Buckhaults, Phillip; Broude, Eugenia; Wyatt, Michael D.; et al. (Scientific reports, 2017)
Keywords: 13/106; 13/89; 14/63; 45/22; 45/44; 45/77; 631/114/2163; 631/67/1059/602; Cancer; Cell growth; Cell Line, Tumor; Cell proliferation; Cell Proliferation - drug effects; Cell survival; Coatomer Protein - antagonists & inhibitors; Coatomer Protein - genetics; Coatomer Protein - metabolism; DEAD-box RNA Helicases - antagonists & inhibitors; DEAD-box RNA Helicases - genetics; DEAD-box RNA Helicases - metabolism; DNA helicase; Drug Design; Drug development; Gene Library; Genomes; Humanities and Social Sciences; Humans; Likelihood Functions; multidisciplinary; Neoplasms - drug therapy; Neoplasms - genetics; Neoplasms - pathology; p53 Protein; Ribosomal Proteins - antagonists & inhibitors; Ribosomal Proteins - genetics; Ribosomal Proteins - metabolism; RNA helicase; RNA Interference; RNA, Small Interfering - metabolism; RNA, Small Interfering - pharmacology; RNA, Small Interfering - therapeutic use; rRNA; Science; Tumor cell lines; Tumor Suppressor Protein p53 - genetics; Tumor Suppressor Protein p53 - metabolism