Persons with Quebec platelet disorder have a tandem duplication of PLAU, the urokinase plasminogen activator gene - Paterson, Andrew D.; Rommens, Johanna M.; Bharaj, Bhupinder; Blavignac, Jessica; Wong, Isidro; Diamandis, Maria; Waye, John S.; Rivard, Georges E.; Hayward, Catherine P.M. (Blood, 2010)
Keywords: Adult; Base Sequence; Biological and medical sciences; Blood Platelet Disorders - blood; Blood Platelet Disorders - diagnosis; Blood Platelet Disorders - genetics; Chromosomes, Human, Pair 10 - genetics; Female; Gene Dosage; Gene Duplication; Hematologic and hematopoietic diseases; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Medical sciences; Molecular Sequence Data; Prognosis; Sequence Homology, Nucleic Acid; Urokinase-Type Plasminogen Activator - genetics; Peptidases; u-Plasminogen activator; Serine endopeptidases; Gene; Hematology; Enzyme; Hydrolases; Genetics; Factor V Quebec; Tandemly repeated sequence; Thrombocytopathy