myCMIE: My cancer molecular information exchange

Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski...

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Published iniScience Vol. 26; no. 8; p. 107324
Main Authors Xu, Qi, Kowalski, Jeanne
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 18.08.2023
Elsevier
Subjects
Biomolecules
Cancer
Health informatics
Molecular physiology
Biomolecules
Molecular physiology
Health informatics
Cancer
Online AccessGet full text
ISSN2589-0042
2589-0042
DOI10.1016/j.isci.2023.107324

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Abstract Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski present a web application, myCMIE, that synthesizes MPR content to define a patient-centric, information system in which molecular profiles are exchanged between a query case(s) and public resources or user-input case series for context-informed treatment and conjecture with therapeutic implication. myCMIE offers an interactive build of coordinately connected digital-twin communities to expand our understanding of treatment context with multiple visuals to stimulate discussions among diverse stakeholders in care. [Display omitted] •myCMIE builds a patient-centric, coordinate molecular information exchange system•myCMIE leverages known with unknown variants to define a total molecular profile•A web-based application for interactive analyses of molecular profile content•A multi-visual presentation of results for multi-stakeholder understanding Health informatics; Biomolecules; Molecular physiology; Cancer
AbstractList Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski present a web application, myCMIE, that synthesizes MPR content to define a patient-centric, information system in which molecular profiles are exchanged between a query case(s) and public resources or user-input case series for context-informed treatment and conjecture with therapeutic implication. myCMIE offers an interactive build of coordinately connected digital-twin communities to expand our understanding of treatment context with multiple visuals to stimulate discussions among diverse stakeholders in care.
Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski present a web application, myCMIE, that synthesizes MPR content to define a patient-centric, information system in which molecular profiles are exchanged between a query case(s) and public resources or user-input case series for context-informed treatment and conjecture with therapeutic implication. myCMIE offers an interactive build of coordinately connected digital-twin communities to expand our understanding of treatment context with multiple visuals to stimulate discussions among diverse stakeholders in care. [Display omitted] •myCMIE builds a patient-centric, coordinate molecular information exchange system•myCMIE leverages known with unknown variants to define a total molecular profile•A web-based application for interactive analyses of molecular profile content•A multi-visual presentation of results for multi-stakeholder understanding Health informatics; Biomolecules; Molecular physiology; Cancer
Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski present a web application, myCMIE, that synthesizes MPR content to define a patient-centric, information system in which molecular profiles are exchanged between a query case(s) and public resources or user-input case series for context-informed treatment and conjecture with therapeutic implication. myCMIE offers an interactive build of coordinately connected digital-twin communities to expand our understanding of treatment context with multiple visuals to stimulate discussions among diverse stakeholders in care. • myCMIE builds a patient-centric, coordinate molecular information exchange system • myCMIE leverages known with unknown variants to define a total molecular profile • A web-based application for interactive analyses of molecular profile content • A multi-visual presentation of results for multi-stakeholder understanding Health informatics; Biomolecules; Molecular physiology; Cancer
Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski present a web application, myCMIE, that synthesizes MPR content to define a patient-centric, information system in which molecular profiles are exchanged between a query case(s) and public resources or user-input case series for context-informed treatment and conjecture with therapeutic implication. myCMIE offers an interactive build of coordinately connected digital-twin communities to expand our understanding of treatment context with multiple visuals to stimulate discussions among diverse stakeholders in care.Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic findings, drugs, and trial options that are challenging to synthesize for effectively and expeditiously informing on treatment. Xu and Kowalski present a web application, myCMIE, that synthesizes MPR content to define a patient-centric, information system in which molecular profiles are exchanged between a query case(s) and public resources or user-input case series for context-informed treatment and conjecture with therapeutic implication. myCMIE offers an interactive build of coordinately connected digital-twin communities to expand our understanding of treatment context with multiple visuals to stimulate discussions among diverse stakeholders in care.
ArticleNumber 107324
Author Xu, Qi
Kowalski, Jeanne
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Issue 8
Keywords Biomolecules
Molecular physiology
Health informatics
Cancer
Language English
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Snippet Molecular profiling reports (MPRs) are critical for determining treatment options for cancer patients. They include several pages of information on genomic...
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SubjectTerms Biomolecules
Cancer
Health informatics
Molecular physiology
Title myCMIE: My cancer molecular information exchange
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Volume 26
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