Pointwise Hölder exponents of a model for skin laser Doppler flowmetry signals based on six nonlinear coupled oscillators with linear and parametric couplings: Comparison with experimental data from young healthy subjects

We study pointwise Hölder exponents of experimental and numerically simulated skin laser Doppler flowmetry (LDF) data that give a peripheral view of the cardiovascular system. The experimental signals are recorded in the forearm of young healthy subjects. The numerically simulated LDF data are compu...

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Published inIngénierie et recherche biomédicale Vol. 31; no. 3; pp. 175 - 181
Main Authors Buard, B., Humeau, A., Rousseau, D., Chapeau-Blondeau, F., Abraham, P.
Format Journal Article
LanguageEnglish
Published Issy-les-Moulineaux Elsevier Masson SAS 2010
Elsevier Masson
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ISSN1959-0318
DOI10.1016/j.irbm.2009.12.003

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Abstract We study pointwise Hölder exponents of experimental and numerically simulated skin laser Doppler flowmetry (LDF) data that give a peripheral view of the cardiovascular system. The experimental signals are recorded in the forearm of young healthy subjects. The numerically simulated LDF data are computed from a model containing six nonlinear coupled oscillators reflecting six almost periodic rhythmic activities present in experimental LDF signals. Simulated LDF signals are for the first time generated with both linear and parametric couplings in order to represent cardiovascular system behaviors. Moreover, we propose the use of a parametric generalised quadratic variation (GQV) based estimation method for the estimation of the pointwise Hölder exponents. The latter identify possible multifractal characteristics of data. The GQV method is first tested on a white noise measure and then applied on the LDF data. The results of our signal processing analysis show that experimental LDF signals recorded in the forearm are weakly multifractal for young healthy subjects at rest. Furthermore, our findings show that the simulated data have a complexity similar to the one of signal recorded in young healthy subjects. However, their pointwise Hölder exponents have differences that we explain. This paper provides useful information to go deeper into the modeling of LDF data, which could bring enlightenment for a better understanding of the peripheral cardiovascular system. Nous analysons dans cet article la complexité des signaux laser Doppler qui donnent une vue périphérique du système cardiovasculaire. Pour cela, des signaux laser Doppler expérimentaux et simulés numériquement sont étudiés. Les signaux expérimentaux sont enregistrés sur l’avant-bras de sujets sains jeunes. Les données simulées sont générées à partir d’un modèle contenant six oscillateurs non linéaires couplés reflétant six activités quasi périodiques présentes dans les signaux expérimentaux. Dans le modèle, les oscillateurs sont couplés avec deux types de couplages, linéaires et paramétriques, afin de représenter au mieux le comportement du système cardiovasculaire. À notre connaissance, de tels signaux n’ont encore jamais été présentés. La complexité de tous les signaux (expérimentaux et simulés) est étudiée par l’estimation des exposants ponctuels de Hölder. Ces derniers identifient des caractéristiques multifractales des données. Les exposants ponctuels de Hölder sont estimés à l’aide d’une méthode basée sur une variation quadratique généralisée paramétrée, préalablement testée sur une mesure de bruit blanc. Les résultats de notre analyse montrent que les signaux laser Doppler expérimentaux enregistrés sur l’avant-bras sont faiblement multifractals pour des sujets sains jeunes au repos. En outre, nos constatations montrent que les données simulées reflètent une complexité similaire à celle des signaux obtenus sur des sujets sains jeunes. Leurs exposants ponctuels de Hölder ont, cependant, des différences que nous explicitons. Cet article fournit des informations utiles pour aller plus loin dans la modélisation des données laser Doppler, ce qui pourrait apporter des éclaircissements pour une meilleure compréhension du système cardiovasculaire périphérique.
AbstractList We study pointwise Hölder exponents of experimental and numerically simulated skin laser Doppler flowmetry (LDF) data that give a peripheral view of the cardiovascular system. The experimental signals are recorded in the forearm of young healthy subjects. The numerically simulated LDF data are computed from a model containing six nonlinear coupled oscillators reflecting six almost periodic rhythmic activities present in experimental LDF signals. Simulated LDF signals are for the first time generated with both linear and parametric couplings in order to represent cardiovascular system behaviors. Moreover, we propose the use of a parametric generalised quadratic variation (GQV) based estimation method for the estimation of the pointwise Hölder exponents. The latter identify possible multifractal characteristics of data. The GQV method is first tested on a white noise measure and then applied on the LDF data. The results of our signal processing analysis show that experimental LDF signals recorded in the forearm are weakly multifractal for young healthy subjects at rest. Furthermore, our findings show that the simulated data have a complexity similar to the one of signal recorded in young healthy subjects. However, their pointwise Hölder exponents have differences that we explain. This paper provides useful information to go deeper into the modeling of LDF data, which could bring enlightenment for a better understanding of the peripheral cardiovascular system. Nous analysons dans cet article la complexité des signaux laser Doppler qui donnent une vue périphérique du système cardiovasculaire. Pour cela, des signaux laser Doppler expérimentaux et simulés numériquement sont étudiés. Les signaux expérimentaux sont enregistrés sur l’avant-bras de sujets sains jeunes. Les données simulées sont générées à partir d’un modèle contenant six oscillateurs non linéaires couplés reflétant six activités quasi périodiques présentes dans les signaux expérimentaux. Dans le modèle, les oscillateurs sont couplés avec deux types de couplages, linéaires et paramétriques, afin de représenter au mieux le comportement du système cardiovasculaire. À notre connaissance, de tels signaux n’ont encore jamais été présentés. La complexité de tous les signaux (expérimentaux et simulés) est étudiée par l’estimation des exposants ponctuels de Hölder. Ces derniers identifient des caractéristiques multifractales des données. Les exposants ponctuels de Hölder sont estimés à l’aide d’une méthode basée sur une variation quadratique généralisée paramétrée, préalablement testée sur une mesure de bruit blanc. Les résultats de notre analyse montrent que les signaux laser Doppler expérimentaux enregistrés sur l’avant-bras sont faiblement multifractals pour des sujets sains jeunes au repos. En outre, nos constatations montrent que les données simulées reflètent une complexité similaire à celle des signaux obtenus sur des sujets sains jeunes. Leurs exposants ponctuels de Hölder ont, cependant, des différences que nous explicitons. Cet article fournit des informations utiles pour aller plus loin dans la modélisation des données laser Doppler, ce qui pourrait apporter des éclaircissements pour une meilleure compréhension du système cardiovasculaire périphérique.
Abstract We study pointwise Hölder exponents of experimental and numerically simulated skin laser Doppler flowmetry (LDF) data that give a peripheral view of the cardiovascular system. The experimental signals are recorded in the forearm of young healthy subjects. The numerically simulated LDF data are computed from a model containing six nonlinear coupled oscillators reflecting six almost periodic rhythmic activities present in experimental LDF signals. Simulated LDF signals are for the first time generated with both linear and parametric couplings in order to represent cardiovascular system behaviors. Moreover, we propose the use of a parametric generalised quadratic variation (GQV) based estimation method for the estimation of the pointwise Hölder exponents. The latter identify possible multifractal characteristics of data. The GQV method is first tested on a white noise measure and then applied on the LDF data. The results of our signal processing analysis show that experimental LDF signals recorded in the forearm are weakly multifractal for young healthy subjects at rest. Furthermore, our findings show that the simulated data have a complexity similar to the one of signal recorded in young healthy subjects. However, their pointwise Hölder exponents have differences that we explain. This paper provides useful information to go deeper into the modeling of LDF data, which could bring enlightenment for a better understanding of the peripheral cardiovascular system.
Author Buard, B.
Rousseau, D.
Abraham, P.
Humeau, A.
Chapeau-Blondeau, F.
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DocumentTitleAlternate Exposants de Hölder ponctuels d’une modélisation de signaux laser Doppler basée sur six oscillateurs couplés non linéaires avec des couplages linéaires et paramétriques : comparaison avec des données expérimentales provenant de sujets sains jeunes
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Issue 3
Keywords Laser Doppler flowmetry
Nonlinear oscillator
Hölder exponent
Multifractality
Multifractalité
Oscillateur non linéaire
Fluxmétrie laser Doppler
Exposant de Hölder
Ingénierie biomédicale
Biomedical engineering
Adulte jeune
Avant bras
Simulation numérique
Exploration ultrason
Donnée expérimentale
Dopplérométrie laser
Modélisation
Couplage linéaire
Homme
Etude comparative
Individu sain
Traitement signal
Génie biomédical
Language English
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Snippet We study pointwise Hölder exponents of experimental and numerically simulated skin laser Doppler flowmetry (LDF) data that give a peripheral view of the...
Abstract We study pointwise Hölder exponents of experimental and numerically simulated skin laser Doppler flowmetry (LDF) data that give a peripheral view of...
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SubjectTerms Biomedical engineering
Coeur et vaisseaux
Exploration par ultrasons
Exposant de Hölder
Fluxmétrie laser Doppler
Hölder exponent
Ingénierie biomédicale
Internal Medicine
Laser Doppler flowmetry
Multifractality
Multifractalité
Nonlinear oscillator
Oscillateur non linéaire
Sciences biologiques et medicales
Sciences medicales
Techniques d'exploration et de diagnostic (generalites)
Title Pointwise Hölder exponents of a model for skin laser Doppler flowmetry signals based on six nonlinear coupled oscillators with linear and parametric couplings: Comparison with experimental data from young healthy subjects
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