Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether - Naon, Deborah; Zaninello, Marta; Giacomello, Marta; Varanita, Tatiana; Grespi, Francesca; Lakshminaranayan, Sowmya; Serafini, Annalisa; Semenzato, Martina; Herkenne, Stephanie; Hernández-Alvarez, Maria Isabel; Zorzano, Antonio; De Stefani, Diego; et al. (Proceedings of the National Academy of Sciences - PNAS, 2016)
Keywords: Animals; Biological Sciences; Calcium; Calcium - metabolism; Calcium Channels - metabolism; Cellular biology; Embryo, Mammalian - cytology; Endoplasmic reticulum; Endoplasmic Reticulum - metabolism; Endoplasmic Reticulum - ultrastructure; Fibroblasts - metabolism; Fibroblasts - ultrastructure; Fluorescence; Gene Deletion; GTP Phosphohydrolases - metabolism; Human Umbilical Vein Endothelial Cells - metabolism; Humans; Liver - metabolism; Mice, Knockout; Microscopy; Mitochondria; Mitochondria - metabolism; Mitochondria - ultrastructure; Molecular Probes - metabolism; Proteins; tethering; Mfn2; interorganellar communication; Ca2; mitochondria