Terazosin-induced alterations in catalase expression and lipid peroxidation in the rat seminal vesicles
Summary Previous studies have shown that alpha1‐adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of...
Saved in:
| Published in | Andrologia Vol. 45; no. 2; pp. 128 - 134 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Germany
Blackwell Publishing Ltd
01.04.2013
John Wiley & Sons, Inc |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0303-4569 1439-0272 1439-0272 |
| DOI | 10.1111/j.1439-0272.2012.01324.x |
Cover
| Abstract | Summary
Previous studies have shown that alpha1‐adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal adult rats. Wistar rats were treated with terazosin (1.2 mg kg−1 body weight, given orally every second day) for 120 days. Catalase expression was assessed immunohistochemically in tissue sections of the seminal vesicles, and lipid peroxidation was estimated by measuring the malondialdehyde (MDA) levels in the seminal vesicles' fluid. The seminal vesicles in terazosin‐treated rats were particularly distended in comparison with those of controls, and their secreting epithelium was suppressed. Cytoplasmic catalase expression in the secreting epithelial cells (% of cells) was increased in terazosin‐treated specimens in comparison with controls (76.1 ± 17.1 versus 51.3 ± 25.1, P = 0.005). MDA levels (μm) were also higher in samples from treated subjects in comparison with controls (2.67 ± 1.19 versus 1.39 ± 0.19, P = 0.01). Although the direct effect of terazosin treatment on the seminal vesicles is that of impaired contractility, an indirect effect is that on fertility by increasing lipid peroxidation in the seminal fluid and/or through degrading of hydrogen peroxide that is essential for sperm capacitation. |
|---|---|
| AbstractList | Summary Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal adult rats. Wistar rats were treated with terazosin (1.2 mg kg-1 body weight, given orally every second day) for 120 days. Catalase expression was assessed immunohistochemically in tissue sections of the seminal vesicles, and lipid peroxidation was estimated by measuring the malondialdehyde (MDA) levels in the seminal vesicles' fluid. The seminal vesicles in terazosin-treated rats were particularly distended in comparison with those of controls, and their secreting epithelium was suppressed. Cytoplasmic catalase expression in the secreting epithelial cells (% of cells) was increased in terazosin-treated specimens in comparison with controls (76.1 ± 17.1 versus 51.3 ± 25.1, P = 0.005). MDA levels (µm) were also higher in samples from treated subjects in comparison with controls (2.67 ± 1.19 versus 1.39 ± 0.19, P = 0.01). Although the direct effect of terazosin treatment on the seminal vesicles is that of impaired contractility, an indirect effect is that on fertility by increasing lipid peroxidation in the seminal fluid and/or through degrading of hydrogen peroxide that is essential for sperm capacitation. [PUBLICATION ABSTRACT] Summary Previous studies have shown that alpha1‐adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal adult rats. Wistar rats were treated with terazosin (1.2 mg kg−1 body weight, given orally every second day) for 120 days. Catalase expression was assessed immunohistochemically in tissue sections of the seminal vesicles, and lipid peroxidation was estimated by measuring the malondialdehyde (MDA) levels in the seminal vesicles' fluid. The seminal vesicles in terazosin‐treated rats were particularly distended in comparison with those of controls, and their secreting epithelium was suppressed. Cytoplasmic catalase expression in the secreting epithelial cells (% of cells) was increased in terazosin‐treated specimens in comparison with controls (76.1 ± 17.1 versus 51.3 ± 25.1, P = 0.005). MDA levels (μm) were also higher in samples from treated subjects in comparison with controls (2.67 ± 1.19 versus 1.39 ± 0.19, P = 0.01). Although the direct effect of terazosin treatment on the seminal vesicles is that of impaired contractility, an indirect effect is that on fertility by increasing lipid peroxidation in the seminal fluid and/or through degrading of hydrogen peroxide that is essential for sperm capacitation. Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal adult rats. Wistar rats were treated with terazosin (1.2 mg kg(-1) body weight, given orally every second day) for 120 days. Catalase expression was assessed immunohistochemically in tissue sections of the seminal vesicles, and lipid peroxidation was estimated by measuring the malondialdehyde (MDA) levels in the seminal vesicles' fluid. The seminal vesicles in terazosin-treated rats were particularly distended in comparison with those of controls, and their secreting epithelium was suppressed. Cytoplasmic catalase expression in the secreting epithelial cells (% of cells) was increased in terazosin-treated specimens in comparison with controls (76.1 ± 17.1 versus 51.3 ± 25.1, P = 0.005). MDA levels (μm) were also higher in samples from treated subjects in comparison with controls (2.67 ± 1.19 versus 1.39 ± 0.19, P = 0.01). Although the direct effect of terazosin treatment on the seminal vesicles is that of impaired contractility, an indirect effect is that on fertility by increasing lipid peroxidation in the seminal fluid and/or through degrading of hydrogen peroxide that is essential for sperm capacitation.Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal adult rats. Wistar rats were treated with terazosin (1.2 mg kg(-1) body weight, given orally every second day) for 120 days. Catalase expression was assessed immunohistochemically in tissue sections of the seminal vesicles, and lipid peroxidation was estimated by measuring the malondialdehyde (MDA) levels in the seminal vesicles' fluid. The seminal vesicles in terazosin-treated rats were particularly distended in comparison with those of controls, and their secreting epithelium was suppressed. Cytoplasmic catalase expression in the secreting epithelial cells (% of cells) was increased in terazosin-treated specimens in comparison with controls (76.1 ± 17.1 versus 51.3 ± 25.1, P = 0.005). MDA levels (μm) were also higher in samples from treated subjects in comparison with controls (2.67 ± 1.19 versus 1.39 ± 0.19, P = 0.01). Although the direct effect of terazosin treatment on the seminal vesicles is that of impaired contractility, an indirect effect is that on fertility by increasing lipid peroxidation in the seminal fluid and/or through degrading of hydrogen peroxide that is essential for sperm capacitation. Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study was designed to investigate the effects of terazosin on the catalase expression in the seminal vesicles and the lipid peroxidation of the seminal fluid in normal adult rats. Wistar rats were treated with terazosin (1.2 mg kg(-1) body weight, given orally every second day) for 120 days. Catalase expression was assessed immunohistochemically in tissue sections of the seminal vesicles, and lipid peroxidation was estimated by measuring the malondialdehyde (MDA) levels in the seminal vesicles' fluid. The seminal vesicles in terazosin-treated rats were particularly distended in comparison with those of controls, and their secreting epithelium was suppressed. Cytoplasmic catalase expression in the secreting epithelial cells (% of cells) was increased in terazosin-treated specimens in comparison with controls (76.1 ± 17.1 versus 51.3 ± 25.1, P = 0.005). MDA levels (μm) were also higher in samples from treated subjects in comparison with controls (2.67 ± 1.19 versus 1.39 ± 0.19, P = 0.01). Although the direct effect of terazosin treatment on the seminal vesicles is that of impaired contractility, an indirect effect is that on fertility by increasing lipid peroxidation in the seminal fluid and/or through degrading of hydrogen peroxide that is essential for sperm capacitation. |
| Author | Patris, E. Kyroudi-Voulgari, A. Mitropoulos, D. Deliconstantinos, G. Anastasiou, I. Perea, D. |
| Author_xml | – sequence: 1 givenname: D. surname: Mitropoulos fullname: Mitropoulos, D. email: Dr Dionisios Mitropoulos, Department of Urology, University of Athens Medical School, Agiou Thoma 17, Athens 11527, Greece.Tel.: + 30 210 770 1141;Fax: + 30 210 770 1141;, dmp@otenet.gr organization: Department of Urology, University of Athens Medical School, Athens, Greece – sequence: 2 givenname: E. surname: Patris fullname: Patris, E. organization: Department of Urology, University of Thrace Medical School, Alexandroupolis, Greece – sequence: 3 givenname: G. surname: Deliconstantinos fullname: Deliconstantinos, G. organization: Department of Experimental Physiology, University of Athens Medical School, Athens, Greece – sequence: 4 givenname: A. surname: Kyroudi-Voulgari fullname: Kyroudi-Voulgari, A. organization: Department of Histology & Embryology, University of Athens Medical School, Athens, Greece – sequence: 5 givenname: I. surname: Anastasiou fullname: Anastasiou, I. organization: Department of Urology, University of Athens Medical School, Athens, Greece – sequence: 6 givenname: D. surname: Perea fullname: Perea, D. organization: Department of Experimental Surgery & Surgical Research, University of Athens Medical School, Athens, Greece |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22731390$$D View this record in MEDLINE/PubMed |
| BookMark | eNqNkc1u1DAUhS1URIfSV0CW2LBJ8F_sZAFSKe2ANJRNEUvLiW_AgycJdkJTnh5npu2iq96FbV1_59i65yU66voOEMKU5DTVu21OBa8ywhTLGaEsJ5Qzkc_P0Orh4gitCCc8E4WsjtFpjFuSShRKCfECHTOmOOUVWaGf1xDMvz66LnOdnRqw2Pgx9UbXdxG7DjdmNN5EwDAPAWJMfWw6i70bnMUDhH52do8v9PgLcBLjCDvXGY__QnSNh_gKPW-Nj3B6t5-g75cX1-efs8239Zfzs03WCF6ITDBqpVEttQWpOClLYeqG1RWtW5tWS-tKUqIYaywHMK2sJaUKSloq2gIR_AS9PfgOof8zQRz1zsUGvDcd9FPUlFMmJRMVT-ibR-i2n0L6dKKEFFXJOJeJen1HTfUOrB6C25lwq-9HmIAPB6AJfYwBWt24cT-PMRjnNSV6iU1v9ZKOXtLRS2x6H5uek0H5yOD-jSdI3x-kN87D7ZN1-uzq03JK-uygd3GE-UFvwm8tFVeF_nG11l-rNZOby0J_5P8ByZa9TA |
| CitedBy_id | crossref_primary_10_1111_and_13800 crossref_primary_10_1111_and_13303 crossref_primary_10_18499_2225_7357_2021_10_3_98_107 |
| Cites_doi | 10.1016/j.ejphar.2008.04.009 10.1016/j.cccn.2004.03.013 10.1254/jjp.61.87 10.1093/geronj/45.2.B52 10.1002/j.1939-4640.2003.tb02730.x 10.1016/0010-7824(90)90043-U 10.1016/S0015-0282(02)04948-8 10.1111/j.1439-0272.1994.tb00766.x 10.1016/S0014-2999(99)00563-4 10.1111/j.1464-410X.2006.06448.x 10.1111/j.1365-2605.1992.tb01114.x 10.1016/0090-4295(81)90474-X 10.1016/0031-9384(82)90272-4 10.1016/S0006-2952(97)00161-5 10.1530/jrf.0.0830169 10.1095/biolreprod.104.028373 10.1111/j.1464-410X.2006.06104.x 10.1113/jphysiol.2003.056002 10.1002/j.1939-4640.1996.tb01823.x 10.1111/j.1365-2605.1994.tb01260.x 10.1093/ajcn/57.5.715S 10.1016/S0890-6238(97)00022-1 10.1002/1097-0045(20000901)44:4<339::AID-PROS12>3.0.CO;2-Z 10.1016/0021-9673(95)00959-0 10.1530/rep.0.1240491 10.1007/BF00176335 10.1111/j.1464-410X.2003.04674.x 10.1111/j.1442-2042.2006.01535.x 10.1016/S0090-4295(00)00744-5 10.1016/S0022-2275(20)33427-1 10.1016/j.lfs.2004.03.011 10.1046/j.1464-410X.2001.00116.x 10.1016/0006-2952(89)90158-5 10.1038/sj.bjp.0701485 10.1046/j.1365-2680.1997.00449.x 10.1038/sj.bjp.0707366 |
| ContentType | Journal Article |
| Copyright | 2012 Blackwell Verlag GmbH 2012 Blackwell Verlag GmbH. Copyright © 2013 Blackwell Verlag GmbH |
| Copyright_xml | – notice: 2012 Blackwell Verlag GmbH – notice: 2012 Blackwell Verlag GmbH. – notice: Copyright © 2013 Blackwell Verlag GmbH |
| DBID | BSCLL AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7TM 7X7 7XB 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M7P PHGZM PHGZT PKEHL PQEST PQGLB PQQKQ PQUKI PRINS 7X8 |
| DOI | 10.1111/j.1439-0272.2012.01324.x |
| DatabaseName | Istex CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Nucleic Acids Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials - QC Biological Science Collection ProQuest Central Natural Science Collection ProQuest One ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) ProQuest Biological Science Collection ProQuest Health & Medical Collection Biological Science Database ProQuest Central Premium ProQuest One Academic (New) ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials Nucleic Acids Abstracts ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Biological Science Collection ProQuest Central (New) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest One Academic UKI Edition ProQuest One Academic ProQuest Central (Alumni) ProQuest One Academic (New) MEDLINE - Academic |
| DatabaseTitleList | ProQuest Central Student MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: http://www.proquest.com/pqcentral?accountid=15518 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1439-0272 |
| EndPage | 134 |
| ExternalDocumentID | 3146215201 22731390 10_1111_j_1439_0272_2012_01324_x AND1324 ark_67375_WNG_M9G26LF5_B |
| Genre | article Journal Article |
| GroupedDBID | --- .3N .GA .GJ .Y3 05W 0R~ 10A 1OB 1OC 23M 24P 31~ 33P 36B 3SF 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5GY 5HH 5LA 5VS 66C 702 7PT 7X7 8-0 8-1 8-3 8-4 8-5 8FI 8FJ 8UM 930 A01 A03 AAESR AAEVG AAKAS AAMMB AANHP AAONW AASGY AAXRX AAZKR ABCQN ABCUV ABDBF ABEML ABLJU ABPVW ABUWG ABXGK ACAHQ ACBWZ ACCMX ACCZN ACGFO ACGFS ACMXC ACPOU ACRPL ACSCC ACUHS ACXBN ACXQS ACYXJ ADBBV ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZCM ADZMN AEFGJ AEGXH AEIMD AENEX AFBPY AFEBI AFFNX AFGKR AFKRA AFZJQ AGQPQ AGXDD AHEFC AI. AIACR AIAGR AIDQK AIDYY AIQQE AIURR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BBNVY BDRZF BENPR BFHJK BHBCM BHPHI BMXJE BROTX BRXPI BSCLL BY8 C45 CAG CCPQU COF CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DUUFO EAD EAP EBC EBD EBS EJD EMB EMK EMOBN ESX EX3 F00 F01 F04 F5P FEDTE FUBAC FYUFA FZ0 G-S G.N GODZA H.X H13 HCIFZ HF~ HMCUK HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M7P MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NF~ O66 O9- OIG OVD P2P P2W P2X P2Z P4B P4D PALCI PHGZM PHGZT PQGLB PQQKQ Q.N Q11 QB0 R.K RIWAO RJQFR ROL RX1 SAMSI SUPJJ SV3 TEORI TUS UB1 UKHRP V8K VH1 W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQJ WVDHM WXI WXSBR XG1 YFH YUY ZXP ~IA ~WT AAYXX CITATION AAJEY CGR CUY CVF ECM EIF NPM 3V. 7TM 7XB 8FE 8FH 8FK AZQEC DWQXO GNUQQ K9. LK8 PKEHL PQEST PQUKI PRINS 7X8 |
| ID | FETCH-LOGICAL-c4354-421d6a7f1d50930884abc2b91bfdb91d1b9610722cd3eeaf6b6117e81871fe043 |
| IEDL.DBID | 7X7 |
| ISSN | 0303-4569 1439-0272 |
| IngestDate | Fri Sep 05 03:10:06 EDT 2025 Fri Jul 25 12:15:12 EDT 2025 Mon Jul 21 06:07:13 EDT 2025 Thu Apr 24 22:50:53 EDT 2025 Wed Oct 01 04:32:44 EDT 2025 Wed Aug 20 07:27:37 EDT 2025 Sun Sep 21 06:18:07 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| License | http://doi.wiley.com/10.1002/tdm_license_1.1 2012 Blackwell Verlag GmbH. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c4354-421d6a7f1d50930884abc2b91bfdb91d1b9610722cd3eeaf6b6117e81871fe043 |
| Notes | ark:/67375/WNG-M9G26LF5-B ArticleID:AND1324 istex:D0947500256E73006CCF1756EB8D26E48426F33E ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| PMID | 22731390 |
| PQID | 1464982336 |
| PQPubID | 2028798 |
| PageCount | 7 |
| ParticipantIDs | proquest_miscellaneous_1312662493 proquest_journals_1464982336 pubmed_primary_22731390 crossref_citationtrail_10_1111_j_1439_0272_2012_01324_x crossref_primary_10_1111_j_1439_0272_2012_01324_x wiley_primary_10_1111_j_1439_0272_2012_01324_x_AND1324 istex_primary_ark_67375_WNG_M9G26LF5_B |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2013-04 April 2013 2013-04-00 2013-Apr 20130401 |
| PublicationDateYYYYMMDD | 2013-04-01 |
| PublicationDate_xml | – month: 04 year: 2013 text: 2013-04 |
| PublicationDecade | 2010 |
| PublicationPlace | Germany |
| PublicationPlace_xml | – name: Germany – name: Berlin |
| PublicationTitle | Andrologia |
| PublicationTitleAlternate | Andrologia |
| PublicationYear | 2013 |
| Publisher | Blackwell Publishing Ltd John Wiley & Sons, Inc |
| Publisher_xml | – name: Blackwell Publishing Ltd – name: John Wiley & Sons, Inc |
| References | Schwinn DA (2001) The role of α1-adrenergic receptor subtypes in lower urinary tract symptoms. BJU Int 88(Suppl 2):27-34. Yono M , Latifpour J , Yamamoto Y , Imanishi A , Yoshida M (2008) Region and age dependent differences in alpha(1)-adrenergic responsiveness of rat seminal vesicle and vas deferens. Eur J Pharmacol 587:291-295. Zubkova EV , Robaire B (2004) Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat. Biol Reprod 71:1002-1008. Markus RP , de Avellar MC (1997) Age-related changes in the reactivity of postsynaptic adrenoceptors in the rat vas deferens: differences between the epididymal and prostatic portion. J Auton Pharmacol 17:147-154. Bohlen D , Hugonnet CL , Mills RD , Weise ES , Schmid HP (2000) Five meters of H(2)O: the pressure at the urinary bladder neck during human ejaculation. Prostate 44:339-341. Sharif SI , Gokhale SD , Chandranath SI (1990) Pharmacological characterization of the postjunctional alpha-adrenoreceptors of rat isolated seminal vesicle. Naunyn-Schmiedeberg's Arch Pharmacol 341:425-431. Yu HJ , Chien CT , Lai YJ , Lai MK , Chen CF , Levin RM , Hsu SM (2003) Hypoxia preconditioning attenuates bladder overdistention-induced oxidative injury by up-regulation of Bcl-2 in the rat. J Phys 554:815-828. Solomon HM , Wier PJ , Ippolito DL , Toscano TV (1997) Effect of prazosin on sperm transport in male rats. Reprod Toxicol 11:627-631. Sofikitis N , Takahashi C , Kadowaki H , Okazaki T , Shimamoto T , Nakamura I , Miyagawa I (1992) The role of seminal vesicles and coagulating glands in fertilization in the rat. Int J Androl 15:54-61. Ratnasooriya WD , Wadsworth RM (1987) Effects of phenoxybenzamine on the fertility of male rats. Med Sci Res 15:961-962. Cabell KS , Ma L , Johnson P (1997) Effects of antihypertensive drugs on rat tissue antioxidant enzyme activities and lipid peroxidation levels. Biochem Pharmacol 54:133-141. Ratnasooriya WD , Wadsworth RM (1994) Tamsulosin, a selective αl-adrenoceptor antagonist, inhibits fertility of male rats. Andrologia 26:107-110. Agarwal A , Saleh RA , Bedaiwy MA (2003) Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 79:829-843. Metafora S , Peluso G , Persico P , Ravagnan G , Esposito C , Porta R (1989) Immunosuppressive and anti-inflammatory properties of a major protein secreted from the epithelium of the rat seminal vesicles. Biochem Pharmacol 38:121-131. Londero D , Logreco P (1996) Automated high-performance liquid chromatographic separation with spectrofluorometric detection of a malondialdehyde-thiobarbituric acid adduct in plasma. J Chromatogr 729:207-210. Moriyama N , Nasu K , Takeuchi T , Akiyama K , Murata S , Nishimatsu H , Yano J , Tsujimoto G , Kawabe K (1997) Quantification and distribution of alpha1-adrenoceptor subtype mRNAs in human vas deferens: comparison with those of epididymal and pelvic portions. Br J Pharmacol 122:1009-1014. Chen H , Cheung MP , Chow PH , Cheung AL , Liu W , O WS (2002) Protection of sperm DNA against oxidative stress in vivo by accessory sex gland secretions in male hamsters. Reproduction 124:491-499. Shima S (1993) Characterization of adrenergic receptors in membranes from the rat seminal vesicle. Jpn J Pharmacol 61:87-92. Kedia KR , Persky L (1981) Effect of phenoxybenzamine (dibenzyline) on sexual function in man. Urology 18:620-621. Griveau JF , Renard P , Lannou D (1994) An in vitro promoting role for hydrogen peroxide in human sperm capacitation. Int J Androl 17:300-307. Kawabe K , Yoshida M , Homma Y , Silodosin Clinical Study Group (2006) Silodosin, a new alpha1A-adrenoceptorselective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo-controlled, doubleblind study in Japanese men. BJU Int 98:1019-1024. Zini A , Schlegel PN (1996) Catalase mRNA expression in the adult male rat reproductive tract. J Androl 17:473-480. Sofikitis N , Takahashi C , Nakamura I , Kadowaki H , Okazaki T , Shimamoto T , Miyagawa I (1990) The role of rat copulatory plug for fertilization. Acta Eur Fertil 21:155-158. Halliwell B , Chirico S (1993) Lipid peroxidation: its mechanism, measurement and significance. Am J Clin Nutr 57(Suppl):715S-725S. Li K , Shang X , Chen Y (2004) High-performance liquid chromatographic detection of lipid peroxidation in human seminal plasma and its application to male infertility. Clin Chim Acta 346:199-203. Giuliano F (2006) Impact of medical treatments for benign prostatic hyperplasia on sexual function. BJU Int 97(Suppl 2):34-38. Ratnasooriya WD , Wadsworth RM (1990) Impairment of fertility of male rats with prazosin. Contraception 41:441-447. Beyer C , Contreras JL , Larsson K , Olmedo M , Morali G (1982) Patterns of motor and seminal vesicle activities during copulation in the male rat. Phys Behav 29:495-500. Sanbe A , Tanaka Y , Fujiwara Y , Tsumura H , Yamauchi J , Cotecchia S , Koike K , Tsujimoto G , Tanoue A (2007) Alpha1-Adrenoceptors are required for normal male sexual function. Br J Pharmacol 152:332-340. Silva MA , Megale A , Avellar MC , Porto CS (1999) Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle. Eur J Pharmacol 381:141-149. Ratnasooriya WD , Ananda UVDS , Ratnasooriya CP (1992) Effect of terazosin, a selective-adrenoceptor antagonist on fertility of male rats. Med Sci Res 20:133-135. Giuliano F , Bernabe J , Droupy S , Alexandre L , Allard J (2004) A comparison of the effects of tamsulosin and alfuzosin on neurally evoked increases in bladder neck and seminal vesicle pressure in rats. BJU Int 93:605-608. Meilhac O , Zhou M , Santanam N , Parthasarathy S (2000) Lipid peroxides induce expression of catalase in cultured endothelial cells. J Lipid Res 41:1205-1213. Peitz B (1988) Effects of seminal vesicle fluid components on sperm motility in the house mouse. J Reprod Fertil 83:169-176. Snyder DL , Pollard M , Wostmann BS , Luckert P (1990) Life span, morphology and pathology of diet-restricted germ-free and conventional Lobund-Wistar rats. J Gerontol 45:B52-B58. Mendes FR , Hamamura M , Queiróz DB , Porto CS , Avellar MC (2004) Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle. Life Sci 75:1449-1463. Debruyne FM (2000) Alpha blockers: are all created equal? Urology 56(Suppl 1):20-22. Hisasue S , Furuya R , Itoh N , Kobayashi K , Furuya S , Tsukamoto T (2006) Ejaculatory disorder caused by alpha-1 adrenoceptor antagonists is not retrograde ejaculation but a loss of seminal emission. Int J Urol 13:1311-1316. Chen H , Chow PH , Cheng SK , Cheung ALM , Cheng LYL , O WS (2003) Male genital tract antioxidant enzymes: their source, function in the female, and ability to preserve sperm DNA integrity in the golden hamster. J Androl 24:704-711. 2006; 97 2004; 346 1996; 17 1996; 729 2006; 13 1993; 61 2006; 98 2000; 44 2000; 41 2003; 79 1994; 26 1992; 15 2008; 587 2001; 88 2003; 554 1990; 341 1987; 15 1990; 41 1993; 57 2004; 75 1990; 21 1990; 45 1982; 29 2004; 93 2004; 71 1997; 11 1997; 54 2000; 56 2002; 124 1999; 381 1997; 122 2007; 152 2003; 24 1986 1997; 17 1981; 18 1988; 83 1994; 17 1992; 20 1989; 38 Ratnasooriya (10.1111/j.1439-0272.2012.01324.x-BIB0026|and1324-cit-0026) 1994; 26 Ratnasooriya (10.1111/j.1439-0272.2012.01324.x-BIB0027|and1324-cit-0027) 1992; 20 Sanbe (10.1111/j.1439-0272.2012.01324.x-BIB0028|and1324-cit-0028) 2007; 152 Meilhac (10.1111/j.1439-0272.2012.01324.x-BIB0019|and1324-cit-0019) 2000; 41 Ratnasooriya (10.1111/j.1439-0272.2012.01324.x-BIB0025|and1324-cit-0025) 1990; 41 Shima (10.1111/j.1439-0272.2012.01324.x-BIB0031|and1324-cit-0031) 1993; 61 Sofikitis (10.1111/j.1439-0272.2012.01324.x-BIB0034|and1324-cit-0034) 1990; 21 Giuliano (10.1111/j.1439-0272.2012.01324.x-BIB0008|and1324-cit-0008) 2006; 97 Ratnasooriya (10.1111/j.1439-0272.2012.01324.x-BIB0024|and1324-cit-0024) 1987; 15 Yono (10.1111/j.1439-0272.2012.01324.x-BIB0037|and1324-cit-0037) 2008; 587 Peitz (10.1111/j.1439-0272.2012.01324.x-BIB0023|and1324-cit-0023) 1988; 83 Silva (10.1111/j.1439-0272.2012.01324.x-BIB0032|and1324-cit-0032) 1999; 381 Yu (10.1111/j.1439-0272.2012.01324.x-BIB0038|and1324-cit-0038) 2003; 554 Beyer (10.1111/j.1439-0272.2012.01324.x-BIB0002|and1324-cit-0002) 1982; 29 Bohlen (10.1111/j.1439-0272.2012.01324.x-BIB0003|and1324-cit-0003) 2000; 44 Mendes (10.1111/j.1439-0272.2012.01324.x-BIB0020|and1324-cit-0020) 2004; 75 Griveau (10.1111/j.1439-0272.2012.01324.x-BIB0011|and1324-cit-0011) 1994; 17 Zini (10.1111/j.1439-0272.2012.01324.x-BIB0039|and1324-cit-0039) 1996; 17 Cabell (10.1111/j.1439-0272.2012.01324.x-BIB0004|and1324-cit-0004) 1997; 54 Londero (10.1111/j.1439-0272.2012.01324.x-BIB0017|and1324-cit-0017) 1996; 729 Sharif (10.1111/j.1439-0272.2012.01324.x-BIB0030|and1324-cit-0030) 1990; 341 Moriyama (10.1111/j.1439-0272.2012.01324.x-BIB0022|and1324-cit-0022) 1997; 122 Kawabe (10.1111/j.1439-0272.2012.01324.x-BIB0014|and1324-cit-0014) 2006; 98 Grisham (10.1111/j.1439-0272.2012.01324.x-BIB0010|and1324-cit-0010) 1986 Markus (10.1111/j.1439-0272.2012.01324.x-BIB0018|and1324-cit-0018) 1997; 17 Halliwell (10.1111/j.1439-0272.2012.01324.x-BIB0012|and1324-cit-0012) 1993; 57 Metafora (10.1111/j.1439-0272.2012.01324.x-BIB0021|and1324-cit-0021) 1989; 38 Chen (10.1111/j.1439-0272.2012.01324.x-BIB0006|and1324-cit-0006) 2003; 24 Snyder (10.1111/j.1439-0272.2012.01324.x-BIB0033|and1324-cit-0033) 1990; 45 Chen (10.1111/j.1439-0272.2012.01324.x-BIB0005|and1324-cit-0005) 2002; 124 Solomon (10.1111/j.1439-0272.2012.01324.x-BIB0036|and1324-cit-0036) 1997; 11 Agarwal (10.1111/j.1439-0272.2012.01324.x-BIB0001|and1324-cit-0001) 2003; 79 Li (10.1111/j.1439-0272.2012.01324.x-BIB0016|and1324-cit-0016) 2004; 346 Kedia (10.1111/j.1439-0272.2012.01324.x-BIB0015|and1324-cit-0015) 1981; 18 Zubkova (10.1111/j.1439-0272.2012.01324.x-BIB0040|and1324-cit-0040) 2004; 71 Debruyne (10.1111/j.1439-0272.2012.01324.x-BIB0007|and1324-cit-0007) 2000; 56 Schwinn (10.1111/j.1439-0272.2012.01324.x-BIB0029|and1324-cit-0029) 2001; 88 Hisasue (10.1111/j.1439-0272.2012.01324.x-BIB0013|and1324-cit-0013) 2006; 13 Sofikitis (10.1111/j.1439-0272.2012.01324.x-BIB0035|and1324-cit-0035) 1992; 15 Giuliano (10.1111/j.1439-0272.2012.01324.x-BIB0009|and1324-cit-0009) 2004; 93 |
| References_xml | – reference: Solomon HM , Wier PJ , Ippolito DL , Toscano TV (1997) Effect of prazosin on sperm transport in male rats. Reprod Toxicol 11:627-631. – reference: Meilhac O , Zhou M , Santanam N , Parthasarathy S (2000) Lipid peroxides induce expression of catalase in cultured endothelial cells. J Lipid Res 41:1205-1213. – reference: Zini A , Schlegel PN (1996) Catalase mRNA expression in the adult male rat reproductive tract. J Androl 17:473-480. – reference: Zubkova EV , Robaire B (2004) Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat. Biol Reprod 71:1002-1008. – reference: Halliwell B , Chirico S (1993) Lipid peroxidation: its mechanism, measurement and significance. Am J Clin Nutr 57(Suppl):715S-725S. – reference: Shima S (1993) Characterization of adrenergic receptors in membranes from the rat seminal vesicle. Jpn J Pharmacol 61:87-92. – reference: Griveau JF , Renard P , Lannou D (1994) An in vitro promoting role for hydrogen peroxide in human sperm capacitation. Int J Androl 17:300-307. – reference: Chen H , Cheung MP , Chow PH , Cheung AL , Liu W , O WS (2002) Protection of sperm DNA against oxidative stress in vivo by accessory sex gland secretions in male hamsters. Reproduction 124:491-499. – reference: Ratnasooriya WD , Wadsworth RM (1987) Effects of phenoxybenzamine on the fertility of male rats. Med Sci Res 15:961-962. – reference: Moriyama N , Nasu K , Takeuchi T , Akiyama K , Murata S , Nishimatsu H , Yano J , Tsujimoto G , Kawabe K (1997) Quantification and distribution of alpha1-adrenoceptor subtype mRNAs in human vas deferens: comparison with those of epididymal and pelvic portions. Br J Pharmacol 122:1009-1014. – reference: Agarwal A , Saleh RA , Bedaiwy MA (2003) Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 79:829-843. – reference: Cabell KS , Ma L , Johnson P (1997) Effects of antihypertensive drugs on rat tissue antioxidant enzyme activities and lipid peroxidation levels. Biochem Pharmacol 54:133-141. – reference: Chen H , Chow PH , Cheng SK , Cheung ALM , Cheng LYL , O WS (2003) Male genital tract antioxidant enzymes: their source, function in the female, and ability to preserve sperm DNA integrity in the golden hamster. J Androl 24:704-711. – reference: Giuliano F , Bernabe J , Droupy S , Alexandre L , Allard J (2004) A comparison of the effects of tamsulosin and alfuzosin on neurally evoked increases in bladder neck and seminal vesicle pressure in rats. BJU Int 93:605-608. – reference: Londero D , Logreco P (1996) Automated high-performance liquid chromatographic separation with spectrofluorometric detection of a malondialdehyde-thiobarbituric acid adduct in plasma. J Chromatogr 729:207-210. – reference: Peitz B (1988) Effects of seminal vesicle fluid components on sperm motility in the house mouse. J Reprod Fertil 83:169-176. – reference: Sanbe A , Tanaka Y , Fujiwara Y , Tsumura H , Yamauchi J , Cotecchia S , Koike K , Tsujimoto G , Tanoue A (2007) Alpha1-Adrenoceptors are required for normal male sexual function. Br J Pharmacol 152:332-340. – reference: Ratnasooriya WD , Wadsworth RM (1990) Impairment of fertility of male rats with prazosin. Contraception 41:441-447. – reference: Ratnasooriya WD , Wadsworth RM (1994) Tamsulosin, a selective αl-adrenoceptor antagonist, inhibits fertility of male rats. Andrologia 26:107-110. – reference: Silva MA , Megale A , Avellar MC , Porto CS (1999) Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle. Eur J Pharmacol 381:141-149. – reference: Snyder DL , Pollard M , Wostmann BS , Luckert P (1990) Life span, morphology and pathology of diet-restricted germ-free and conventional Lobund-Wistar rats. J Gerontol 45:B52-B58. – reference: Bohlen D , Hugonnet CL , Mills RD , Weise ES , Schmid HP (2000) Five meters of H(2)O: the pressure at the urinary bladder neck during human ejaculation. Prostate 44:339-341. – reference: Ratnasooriya WD , Ananda UVDS , Ratnasooriya CP (1992) Effect of terazosin, a selective-adrenoceptor antagonist on fertility of male rats. Med Sci Res 20:133-135. – reference: Sofikitis N , Takahashi C , Nakamura I , Kadowaki H , Okazaki T , Shimamoto T , Miyagawa I (1990) The role of rat copulatory plug for fertilization. Acta Eur Fertil 21:155-158. – reference: Metafora S , Peluso G , Persico P , Ravagnan G , Esposito C , Porta R (1989) Immunosuppressive and anti-inflammatory properties of a major protein secreted from the epithelium of the rat seminal vesicles. Biochem Pharmacol 38:121-131. – reference: Markus RP , de Avellar MC (1997) Age-related changes in the reactivity of postsynaptic adrenoceptors in the rat vas deferens: differences between the epididymal and prostatic portion. J Auton Pharmacol 17:147-154. – reference: Yono M , Latifpour J , Yamamoto Y , Imanishi A , Yoshida M (2008) Region and age dependent differences in alpha(1)-adrenergic responsiveness of rat seminal vesicle and vas deferens. Eur J Pharmacol 587:291-295. – reference: Kawabe K , Yoshida M , Homma Y , Silodosin Clinical Study Group (2006) Silodosin, a new alpha1A-adrenoceptorselective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo-controlled, doubleblind study in Japanese men. BJU Int 98:1019-1024. – reference: Sharif SI , Gokhale SD , Chandranath SI (1990) Pharmacological characterization of the postjunctional alpha-adrenoreceptors of rat isolated seminal vesicle. Naunyn-Schmiedeberg's Arch Pharmacol 341:425-431. – reference: Yu HJ , Chien CT , Lai YJ , Lai MK , Chen CF , Levin RM , Hsu SM (2003) Hypoxia preconditioning attenuates bladder overdistention-induced oxidative injury by up-regulation of Bcl-2 in the rat. J Phys 554:815-828. – reference: Mendes FR , Hamamura M , Queiróz DB , Porto CS , Avellar MC (2004) Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle. Life Sci 75:1449-1463. – reference: Debruyne FM (2000) Alpha blockers: are all created equal? Urology 56(Suppl 1):20-22. – reference: Giuliano F (2006) Impact of medical treatments for benign prostatic hyperplasia on sexual function. BJU Int 97(Suppl 2):34-38. – reference: Sofikitis N , Takahashi C , Kadowaki H , Okazaki T , Shimamoto T , Nakamura I , Miyagawa I (1992) The role of seminal vesicles and coagulating glands in fertilization in the rat. Int J Androl 15:54-61. – reference: Schwinn DA (2001) The role of α1-adrenergic receptor subtypes in lower urinary tract symptoms. BJU Int 88(Suppl 2):27-34. – reference: Beyer C , Contreras JL , Larsson K , Olmedo M , Morali G (1982) Patterns of motor and seminal vesicle activities during copulation in the male rat. Phys Behav 29:495-500. – reference: Hisasue S , Furuya R , Itoh N , Kobayashi K , Furuya S , Tsukamoto T (2006) Ejaculatory disorder caused by alpha-1 adrenoceptor antagonists is not retrograde ejaculation but a loss of seminal emission. Int J Urol 13:1311-1316. – reference: Kedia KR , Persky L (1981) Effect of phenoxybenzamine (dibenzyline) on sexual function in man. Urology 18:620-621. – reference: Li K , Shang X , Chen Y (2004) High-performance liquid chromatographic detection of lipid peroxidation in human seminal plasma and its application to male infertility. Clin Chim Acta 346:199-203. – volume: 11 start-page: 627 year: 1997 end-page: 631 article-title: Effect of prazosin on sperm transport in male rats publication-title: Reprod Toxicol – volume: 346 start-page: 199 year: 2004 end-page: 203 article-title: High‐performance liquid chromatographic detection of lipid peroxidation in human seminal plasma and its application to male infertility publication-title: Clin Chim Acta – volume: 41 start-page: 441 year: 1990 end-page: 447 article-title: Impairment of fertility of male rats with prazosin publication-title: Contraception – volume: 54 start-page: 133 year: 1997 end-page: 141 article-title: Effects of antihypertensive drugs on rat tissue antioxidant enzyme activities and lipid peroxidation levels publication-title: Biochem Pharmacol – start-page: 1 year: 1986 end-page: 18 article-title: Chemistry and cytotoxicity of reactive oxygen metabolites – volume: 17 start-page: 147 year: 1997 end-page: 154 article-title: Age‐related changes in the reactivity of postsynaptic adrenoceptors in the rat vas deferens: differences between the epididymal and prostatic portion publication-title: J Auton Pharmacol – volume: 341 start-page: 425 year: 1990 end-page: 431 article-title: Pharmacological characterization of the postjunctional alpha‐adrenoreceptors of rat isolated seminal vesicle publication-title: Naunyn‐Schmiedeberg's Arch Pharmacol – volume: 45 start-page: B52 year: 1990 end-page: B58 article-title: Life span, morphology and pathology of diet‐restricted germ‐free and conventional Lobund‐Wistar rats publication-title: J Gerontol – volume: 97 start-page: 34 issue: Suppl 2 year: 2006 end-page: 38 article-title: Impact of medical treatments for benign prostatic hyperplasia on sexual function publication-title: BJU Int – volume: 83 start-page: 169 year: 1988 end-page: 176 article-title: Effects of seminal vesicle fluid components on sperm motility in the house mouse publication-title: J Reprod Fertil – volume: 21 start-page: 155 year: 1990 end-page: 158 article-title: The role of rat copulatory plug for fertilization publication-title: Acta Eur Fertil – volume: 15 start-page: 54 year: 1992 end-page: 61 article-title: The role of seminal vesicles and coagulating glands in fertilization in the rat publication-title: Int J Androl – volume: 79 start-page: 829 year: 2003 end-page: 843 article-title: Role of reactive oxygen species in the pathophysiology of human reproduction publication-title: Fertil Steril – volume: 554 start-page: 815 year: 2003 end-page: 828 article-title: Hypoxia preconditioning attenuates bladder overdistention‐induced oxidative injury by up‐regulation of Bcl‐2 in the rat publication-title: J Phys – volume: 41 start-page: 1205 year: 2000 end-page: 1213 article-title: Lipid peroxides induce expression of catalase in cultured endothelial cells publication-title: J Lipid Res – volume: 93 start-page: 605 year: 2004 end-page: 608 article-title: A comparison of the effects of tamsulosin and alfuzosin on neurally evoked increases in bladder neck and seminal vesicle pressure in rats publication-title: BJU Int – volume: 56 start-page: 20 issue: Suppl 1 year: 2000 end-page: 22 article-title: Alpha blockers: are all created equal? publication-title: Urology – volume: 26 start-page: 107 year: 1994 end-page: 110 article-title: Tamsulosin, a selective αl‐adrenoceptor antagonist, inhibits fertility of male rats publication-title: Andrologia – volume: 71 start-page: 1002 year: 2004 end-page: 1008 article-title: Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat publication-title: Biol Reprod – volume: 17 start-page: 300 year: 1994 end-page: 307 article-title: An promoting role for hydrogen peroxide in human sperm capacitation publication-title: Int J Androl – volume: 98 start-page: 1019 year: 2006 end-page: 1024 article-title: Silodosin, a new alpha1A‐adrenoceptorselective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo‐controlled, doubleblind study in Japanese men publication-title: BJU Int – volume: 75 start-page: 1449 year: 2004 end-page: 1463 article-title: Effects of androgen manipulation on alpha1‐adrenoceptor subtypes in the rat seminal vesicle publication-title: Life Sci – volume: 44 start-page: 339 year: 2000 end-page: 341 article-title: Five meters of H(2)O: the pressure at the urinary bladder neck during human ejaculation publication-title: Prostate – volume: 122 start-page: 1009 year: 1997 end-page: 1014 article-title: Quantification and distribution of alpha1‐adrenoceptor subtype mRNAs in human vas deferens: comparison with those of epididymal and pelvic portions publication-title: Br J Pharmacol – volume: 17 start-page: 473 year: 1996 end-page: 480 article-title: Catalase mRNA expression in the adult male rat reproductive tract publication-title: J Androl – volume: 124 start-page: 491 year: 2002 end-page: 499 article-title: Protection of sperm DNA against oxidative stress by accessory sex gland secretions in male hamsters publication-title: Reproduction – volume: 61 start-page: 87 year: 1993 end-page: 92 article-title: Characterization of adrenergic receptors in membranes from the rat seminal vesicle publication-title: Jpn J Pharmacol – volume: 152 start-page: 332 year: 2007 end-page: 340 article-title: Alpha1‐Adrenoceptors are required for normal male sexual function publication-title: Br J Pharmacol – volume: 381 start-page: 141 year: 1999 end-page: 149 article-title: Expression and pharmacological characterization of alpha1‐adrenoceptors in rat seminal vesicle publication-title: Eur J Pharmacol – volume: 29 start-page: 495 year: 1982 end-page: 500 article-title: Patterns of motor and seminal vesicle activities during copulation in the male rat publication-title: Phys Behav – volume: 15 start-page: 961 year: 1987 end-page: 962 article-title: Effects of phenoxybenzamine on the fertility of male rats publication-title: Med Sci Res – volume: 57 start-page: 715S issue: Suppl year: 1993 end-page: 725S article-title: Lipid peroxidation: its mechanism, measurement and significance publication-title: Am J Clin Nutr – volume: 18 start-page: 620 year: 1981 end-page: 621 article-title: Effect of phenoxybenzamine (dibenzyline) on sexual function in man publication-title: Urology – volume: 20 start-page: 133 year: 1992 end-page: 135 article-title: Effect of terazosin, a selective‐adrenoceptor antagonist on fertility of male rats publication-title: Med Sci Res – volume: 24 start-page: 704 year: 2003 end-page: 711 article-title: Male genital tract antioxidant enzymes: their source, function in the female, and ability to preserve sperm DNA integrity in the golden hamster publication-title: J Androl – volume: 587 start-page: 291 year: 2008 end-page: 295 article-title: Region and age dependent differences in alpha(1)‐adrenergic responsiveness of rat seminal vesicle and vas deferens publication-title: Eur J Pharmacol – volume: 88 start-page: 27 issue: Suppl 2 year: 2001 end-page: 34 article-title: The role of α1‐adrenergic receptor subtypes in lower urinary tract symptoms publication-title: BJU Int – volume: 13 start-page: 1311 year: 2006 end-page: 1316 article-title: Ejaculatory disorder caused by alpha‐1 adrenoceptor antagonists is not retrograde ejaculation but a loss of seminal emission publication-title: Int J Urol – volume: 729 start-page: 207 year: 1996 end-page: 210 article-title: Automated high‐performance liquid chromatographic separation with spectrofluorometric detection of a malondialdehyde‐thiobarbituric acid adduct in plasma publication-title: J Chromatogr – volume: 38 start-page: 121 year: 1989 end-page: 131 article-title: Immunosuppressive and anti‐inflammatory properties of a major protein secreted from the epithelium of the rat seminal vesicles publication-title: Biochem Pharmacol – volume: 587 start-page: 291 year: 2008 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0037|and1324-cit-0037 article-title: Region and age dependent differences in alpha(1)-adrenergic responsiveness of rat seminal vesicle and vas deferens publication-title: Eur J Pharmacol doi: 10.1016/j.ejphar.2008.04.009 – volume: 346 start-page: 199 year: 2004 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0016|and1324-cit-0016 article-title: High-performance liquid chromatographic detection of lipid peroxidation in human seminal plasma and its application to male infertility publication-title: Clin Chim Acta doi: 10.1016/j.cccn.2004.03.013 – volume: 61 start-page: 87 year: 1993 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0031|and1324-cit-0031 article-title: Characterization of adrenergic receptors in membranes from the rat seminal vesicle publication-title: Jpn J Pharmacol doi: 10.1254/jjp.61.87 – start-page: 1 volume-title: Physiology of Oxygen Radicals year: 1986 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0010|and1324-cit-0010 article-title: Chemistry and cytotoxicity of reactive oxygen metabolites – volume: 45 start-page: B52 year: 1990 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0033|and1324-cit-0033 article-title: Life span, morphology and pathology of diet-restricted germ-free and conventional Lobund-Wistar rats publication-title: J Gerontol doi: 10.1093/geronj/45.2.B52 – volume: 24 start-page: 704 year: 2003 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0006|and1324-cit-0006 article-title: Male genital tract antioxidant enzymes: their source, function in the female, and ability to preserve sperm DNA integrity in the golden hamster publication-title: J Androl doi: 10.1002/j.1939-4640.2003.tb02730.x – volume: 41 start-page: 441 year: 1990 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0025|and1324-cit-0025 article-title: Impairment of fertility of male rats with prazosin publication-title: Contraception doi: 10.1016/0010-7824(90)90043-U – volume: 79 start-page: 829 year: 2003 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0001|and1324-cit-0001 article-title: Role of reactive oxygen species in the pathophysiology of human reproduction publication-title: Fertil Steril doi: 10.1016/S0015-0282(02)04948-8 – volume: 26 start-page: 107 year: 1994 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0026|and1324-cit-0026 article-title: Tamsulosin, a selective αl-adrenoceptor antagonist, inhibits fertility of male rats publication-title: Andrologia doi: 10.1111/j.1439-0272.1994.tb00766.x – volume: 20 start-page: 133 year: 1992 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0027|and1324-cit-0027 article-title: Effect of terazosin, a selective-adrenoceptor antagonist on fertility of male rats publication-title: Med Sci Res – volume: 381 start-page: 141 year: 1999 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0032|and1324-cit-0032 article-title: Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle publication-title: Eur J Pharmacol doi: 10.1016/S0014-2999(99)00563-4 – volume: 98 start-page: 1019 year: 2006 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0014|and1324-cit-0014 article-title: Silodosin, a new alpha1A-adrenoceptorselective antagonist for treating benign prostatic hyperplasia: results of a phase III randomized, placebo-controlled, doubleblind study in Japanese men publication-title: BJU Int doi: 10.1111/j.1464-410X.2006.06448.x – volume: 15 start-page: 54 year: 1992 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0035|and1324-cit-0035 article-title: The role of seminal vesicles and coagulating glands in fertilization in the rat publication-title: Int J Androl doi: 10.1111/j.1365-2605.1992.tb01114.x – volume: 18 start-page: 620 year: 1981 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0015|and1324-cit-0015 article-title: Effect of phenoxybenzamine (dibenzyline) on sexual function in man publication-title: Urology doi: 10.1016/0090-4295(81)90474-X – volume: 29 start-page: 495 year: 1982 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0002|and1324-cit-0002 article-title: Patterns of motor and seminal vesicle activities during copulation in the male rat publication-title: Phys Behav doi: 10.1016/0031-9384(82)90272-4 – volume: 54 start-page: 133 year: 1997 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0004|and1324-cit-0004 article-title: Effects of antihypertensive drugs on rat tissue antioxidant enzyme activities and lipid peroxidation levels publication-title: Biochem Pharmacol doi: 10.1016/S0006-2952(97)00161-5 – volume: 83 start-page: 169 year: 1988 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0023|and1324-cit-0023 article-title: Effects of seminal vesicle fluid components on sperm motility in the house mouse publication-title: J Reprod Fertil doi: 10.1530/jrf.0.0830169 – volume: 71 start-page: 1002 year: 2004 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0040|and1324-cit-0040 article-title: Effect of glutathione depletion on antioxidant enzymes in the epididymis, seminal vesicles, and liver and on spermatozoa motility in the aging brown Norway rat publication-title: Biol Reprod doi: 10.1095/biolreprod.104.028373 – volume: 97 start-page: 34 issue: Suppl 2 year: 2006 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0008|and1324-cit-0008 article-title: Impact of medical treatments for benign prostatic hyperplasia on sexual function publication-title: BJU Int doi: 10.1111/j.1464-410X.2006.06104.x – volume: 15 start-page: 961 year: 1987 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0024|and1324-cit-0024 article-title: Effects of phenoxybenzamine on the fertility of male rats publication-title: Med Sci Res – volume: 554 start-page: 815 year: 2003 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0038|and1324-cit-0038 article-title: Hypoxia preconditioning attenuates bladder overdistention-induced oxidative injury by up-regulation of Bcl-2 in the rat publication-title: J Phys doi: 10.1113/jphysiol.2003.056002 – volume: 17 start-page: 473 year: 1996 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0039|and1324-cit-0039 article-title: Catalase mRNA expression in the adult male rat reproductive tract publication-title: J Androl doi: 10.1002/j.1939-4640.1996.tb01823.x – volume: 17 start-page: 300 year: 1994 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0011|and1324-cit-0011 article-title: An in vitro promoting role for hydrogen peroxide in human sperm capacitation publication-title: Int J Androl doi: 10.1111/j.1365-2605.1994.tb01260.x – volume: 57 start-page: 715S issue: Suppl year: 1993 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0012|and1324-cit-0012 article-title: Lipid peroxidation: its mechanism, measurement and significance publication-title: Am J Clin Nutr doi: 10.1093/ajcn/57.5.715S – volume: 11 start-page: 627 year: 1997 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0036|and1324-cit-0036 article-title: Effect of prazosin on sperm transport in male rats publication-title: Reprod Toxicol doi: 10.1016/S0890-6238(97)00022-1 – volume: 44 start-page: 339 year: 2000 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0003|and1324-cit-0003 article-title: Five meters of H(2)O: the pressure at the urinary bladder neck during human ejaculation publication-title: Prostate doi: 10.1002/1097-0045(20000901)44:4<339::AID-PROS12>3.0.CO;2-Z – volume: 729 start-page: 207 year: 1996 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0017|and1324-cit-0017 article-title: Automated high-performance liquid chromatographic separation with spectrofluorometric detection of a malondialdehyde-thiobarbituric acid adduct in plasma publication-title: J Chromatogr doi: 10.1016/0021-9673(95)00959-0 – volume: 124 start-page: 491 year: 2002 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0005|and1324-cit-0005 article-title: Protection of sperm DNA against oxidative stress in vivo by accessory sex gland secretions in male hamsters publication-title: Reproduction doi: 10.1530/rep.0.1240491 – volume: 341 start-page: 425 year: 1990 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0030|and1324-cit-0030 article-title: Pharmacological characterization of the postjunctional alpha-adrenoreceptors of rat isolated seminal vesicle publication-title: Naunyn-Schmiedeberg's Arch Pharmacol doi: 10.1007/BF00176335 – volume: 93 start-page: 605 year: 2004 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0009|and1324-cit-0009 article-title: A comparison of the effects of tamsulosin and alfuzosin on neurally evoked increases in bladder neck and seminal vesicle pressure in rats publication-title: BJU Int doi: 10.1111/j.1464-410X.2003.04674.x – volume: 13 start-page: 1311 year: 2006 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0013|and1324-cit-0013 article-title: Ejaculatory disorder caused by alpha-1 adrenoceptor antagonists is not retrograde ejaculation but a loss of seminal emission publication-title: Int J Urol doi: 10.1111/j.1442-2042.2006.01535.x – volume: 56 start-page: 20 issue: Suppl 1 year: 2000 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0007|and1324-cit-0007 article-title: Alpha blockers: are all created equal? publication-title: Urology doi: 10.1016/S0090-4295(00)00744-5 – volume: 41 start-page: 1205 year: 2000 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0019|and1324-cit-0019 article-title: Lipid peroxides induce expression of catalase in cultured endothelial cells publication-title: J Lipid Res doi: 10.1016/S0022-2275(20)33427-1 – volume: 75 start-page: 1449 year: 2004 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0020|and1324-cit-0020 article-title: Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle publication-title: Life Sci doi: 10.1016/j.lfs.2004.03.011 – volume: 21 start-page: 155 year: 1990 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0034|and1324-cit-0034 article-title: The role of rat copulatory plug for fertilization publication-title: Acta Eur Fertil – volume: 88 start-page: 27 issue: Suppl 2 year: 2001 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0029|and1324-cit-0029 article-title: The role of α1-adrenergic receptor subtypes in lower urinary tract symptoms publication-title: BJU Int doi: 10.1046/j.1464-410X.2001.00116.x – volume: 38 start-page: 121 year: 1989 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0021|and1324-cit-0021 article-title: Immunosuppressive and anti-inflammatory properties of a major protein secreted from the epithelium of the rat seminal vesicles publication-title: Biochem Pharmacol doi: 10.1016/0006-2952(89)90158-5 – volume: 122 start-page: 1009 year: 1997 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0022|and1324-cit-0022 article-title: Quantification and distribution of alpha1-adrenoceptor subtype mRNAs in human vas deferens: comparison with those of epididymal and pelvic portions publication-title: Br J Pharmacol doi: 10.1038/sj.bjp.0701485 – volume: 17 start-page: 147 year: 1997 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0018|and1324-cit-0018 article-title: Age-related changes in the reactivity of postsynaptic adrenoceptors in the rat vas deferens: differences between the epididymal and prostatic portion publication-title: J Auton Pharmacol doi: 10.1046/j.1365-2680.1997.00449.x – volume: 152 start-page: 332 year: 2007 ident: 10.1111/j.1439-0272.2012.01324.x-BIB0028|and1324-cit-0028 article-title: Alpha1-Adrenoceptors are required for normal male sexual function publication-title: Br J Pharmacol doi: 10.1038/sj.bjp.0707366 |
| SSID | ssj0000457744 ssj0012829 |
| Score | 1.9709833 |
| Snippet | Summary
Previous studies have shown that alpha1‐adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This... Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This study... Summary Previous studies have shown that alpha1-adrenergic receptor antagonists may alter seminal vesicle contractility and impair fertility in male rats. This... |
| SourceID | proquest pubmed crossref wiley istex |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 128 |
| SubjectTerms | Adrenergic alpha-1 Receptor Antagonists - toxicity Alpha-adrenoreceptor antagonists Animals catalase Catalase - metabolism Fertility - drug effects lipid peroxidation Lipid Peroxidation - drug effects Male Prazosin - analogs & derivatives Prazosin - toxicity rat prostate Rats Rats, Wistar Seminal Vesicles - drug effects Seminal Vesicles - metabolism Seminal Vesicles - pathology terazosin |
| SummonAdditionalLinks | – databaseName: Wiley Online Library - Core collection (SURFmarket) dbid: DR2 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9tAEB5KCqWXvtuoTcsWSm8y3odX0jF9OKE0PpSE5rbsalcgHORg2cXk1J_Q39hf0pmVLOqQQyi9CIE0eqxmdr-ZbzQD8A6dBqVdXqWTkvtUVaVMrQoydQ59sSyP7BBlW8z08Zn6cj457_Of6F-Yrj7EEHAjy4jzNRm4de01I5cFcZD0PxWF9NCxUiPCk1xOImP7TQzhFkQuWSz03hMMRCB2BINMEUMUu0k-N154Z-W6Sx9hcxMs3UW5cZmaPoT59gW77JT5aL1yo_LqWu3H_zMCj-BBj2bZYad-j-FOaJ7AvZOer38K9WlY2qtFWze_f_5C7x_1yLNI0HeBQlY3LAaQcC1lYdMn5TbMNp5d1Je1Z1THfFN3jZ_obMSrDIVZG2I3MvYjtDGx7xmcTT-ffjxO--YOaYkITaVKcK9tVnGPkEXiXKesK4UruKs8bj13BSK7TIjSyxBspZ3mPAuILzJehbGSz2GvWTRhH5jTwlK9Ze0rq8ZBuMrlEfh6neManSeQbT-cKfvK59SA48L87QHJwtBIGhpJE0fSbBLgg-RlV_3jFjLvo24MAnY5p-y5bGK-z47MSXEk9NfpxHxI4GCrPKafOFryxFSRCyl1Am-Hw2jyxOPYJizWeI7kCKvQb5YJvOiUbriZQDiKoH6cgI6qc-vHNoezT7T38l8FX8F9EVuFUFbTAeytluvwGgHbyr2JpvgHheUs9w priority: 102 providerName: Wiley-Blackwell |
| Title | Terazosin-induced alterations in catalase expression and lipid peroxidation in the rat seminal vesicles |
| URI | https://api.istex.fr/ark:/67375/WNG-M9G26LF5-B/fulltext.pdf https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1439-0272.2012.01324.x https://www.ncbi.nlm.nih.gov/pubmed/22731390 https://www.proquest.com/docview/1464982336 https://www.proquest.com/docview/1312662493 |
| Volume | 45 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVEBS databaseName: EBSCOhost Academic Search Ultimate customDbUrl: https://search.ebscohost.com/login.aspx?authtype=ip,shib&custid=s3936755&profile=ehost&defaultdb=asn eissn: 1439-0272 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0012829 issn: 0303-4569 databaseCode: ABDBF dateStart: 19980201 isFulltext: true titleUrlDefault: https://search.ebscohost.com/direct.asp?db=asn providerName: EBSCOhost – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1439-0272 dateEnd: 20171231 omitProxy: true ssIdentifier: ssj0012829 issn: 0303-4569 databaseCode: 7X7 dateStart: 20120801 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: http://www.proquest.com/pqcentral?accountid=15518 eissn: 1439-0272 dateEnd: 20171231 omitProxy: true ssIdentifier: ssj0012829 issn: 0303-4569 databaseCode: BENPR dateStart: 20120801 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVWIB databaseName: Wiley Online Library - Core collection (SURFmarket) issn: 0303-4569 databaseCode: DR2 dateStart: 19970101 customDbUrl: isFulltext: true eissn: 1439-0272 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0012829 providerName: Wiley-Blackwell |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3da9swED-2BsZeSvdZb13RYOzNLPqIbD-Ndm1axhpGaVnehGTJI6w4WdKOsL--d7LirTBGX4yNdVjoTrrfffgO4B0aDUq7sslHNfe5amqZWxVk7hzaYkUZo0OUbTHRp5fq83Q0TQ63VUqr3JyJ8aD285p85B9wR6uqFFLqj4ufOXWNouhqaqHxEAYcoQpJdTHtDS5OUcK72TuofilqSX9gkRMQTTG1KXqUVNKAVnf9L7x5F75G_TPege0EHNlBx-kn8CC0T-HRWQqNP4PvF2Fpf8_R9M_RzEaGeRYj4Z1Hjs1aFj01qLRYWKfs15bZ1rOr2WLmGRUMX8-6Dks0GoEhQ2K2CrHtF_sVVjGD7jlcjo8vPp3mqYtCXiMUUrkS3GtbNNwjNpB4qCjrauEq7hqPV89dhRCqEKL2MgTbaKc5LwIq8oI3YajkC9hq523YBea0sFTYWPvGqmEQrnFlRJhel6gMywyKzUKaOpUYp04XV-ZvU0NWhlhgiAUmssCsM-A95aIrs3EPmveRVz2BXf6gNLViZL5NTsxZdSL0l_HIHGawt2GmSTt0Zf7IUwZv-9e4tyhgYtswv8ExkiN-QQNVZvCyE4L-YwJxH6LnYQY6SsW9p20OJkd09-r_s3oNj0XsvEFJQnuwdb28CW8Q_1y7_Sjk-zA4PJ58Pceno3NxCzXH_5k |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VVgIuiDeGAosE3Cyyj6ydA0KFkqY0ySkVuS1e7xpFVE6IWwj8KH4jM-sHVEKol14sS96xVzuzO988PAPwHI0GpW1axP2cu1gVuYwz5WVsLdpiSRqiQ5RtMdWjY_Vh3p9vwa_2XxhKq2zPxHBQu2VOPvJXuKPVIBVS6jerrzF1jaLoattCoxaLI__jO5ps1evDfeTvCyGG72fvRnHTVSDOERqoWAnudJYU3KGulLjJVGZzYQfcFg6vjtsBQopEiNxJ77NCW8154lGxJbzwPSXxvVdgR8meolr9ybwz8DhFJc9nC6G6pygp_fFFTkc0_VRbZKlRgTvEzc2_8O15uBz03fAm3GiAKturJesWbPnyNlydNKH4O_B55tfZz2W1KGM061FAHAuR99oDyBYlC54hVJLMb5ps25JlpWMni9XCMSpQvlnUHZ1oNAJRhsSs8qHNGPvmq5CxdxeOL2V978F2uSz9A2BWi4wKKWtXZKrnhS1sGhCt0ykq3zSCpF1Ikzclzamzxon527SRA0MsMMQCE1hgNhHwjnJVl_W4AM3LwKuOIFt_obS4pG8-Tg_MZHAg9HjYN28j2G2ZaZoToTJ_5DeCZ91j3MsUoMlKvzzDMZIjXkKDWEZwvxaC7mMCcSai9V4EOkjFhadt9qb7dPfw_7N6CtdGs8nYjA-nR4_gughdPyhBaRe2T9dn_jFir1P7JAg8g0-XvcN-A7-4OSk |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQK1VceEMDLRgJcctq_VgnOZaWbYF2hVArerPs2JairbKrfaBVT_wEfiO_hBknG7FVDxXiEkWJJw97xv7m4RlC3oHSIJXNQzoomUtlKEVqpBeptaCLZXn0DmG0xUidXMjPl4PLNv4J98I0-SE6gxtKRpyvUcCnLtwQclGgDxL3U6FJDxQr2QM8uS0VXEWA9I139haALlnM9N56GNCD2HgYRAogotiM8rn1yRtL1zaOwuo2XLoJc-M6NXxIxus_bMJTxr3lwvbK6xvJH_9PFzwiD1o4Sw8a_ntM7vn6Cdk5ax32T0l17mfmejKv6t8_f4H6D4zkaPTQN5ZCWtU0WpBgMaV-1Ubl1tTUjl5V08pRTGS-qprKT9gaACsFYjr3sRwZ_eHnMbLvGbkYfjw_PEnb6g5pCRBNppIzp0wWmAPMImCyk8aW3BbMBgdHx2wB0C7jvHTCexOUVYxlHgBGxoLvS_GcbNWT2u8SahU3mHBZuWBk33MbbB6Rr1M5LNJ5QrL1wOmyTX2OFTiu9N8qkCg09qTGntSxJ_UqIayjnDbpP-5A8z7yRkdgZmMMn8sG-vvoWJ8Vx1ydDgf6Q0L21syj25ljjqqYLHIuhErI2-42yDw6ckztJ0toIxjgKlCcRUJeNEzXvYwDHgVU30-Iiqxz58_WB6MjPHv5r4RvyM7Xo6E-_TT68orc57FsCEY47ZGtxWzp9wG8LezrKJV_AIuDL8I |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Terazosin-induced+alterations+in+catalase+expression+and+lipid+peroxidation+in+the+rat+seminal+vesicles&rft.jtitle=Andrologia&rft.au=Mitropoulos%2C+D.&rft.au=Patris%2C+E.&rft.au=Deliconstantinos%2C+G.&rft.au=Kyroudi-Voulgari%2C+A.&rft.date=2013-04-01&rft.pub=Blackwell+Publishing+Ltd&rft.issn=0303-4569&rft.eissn=1439-0272&rft.volume=45&rft.issue=2&rft.spage=128&rft.epage=134&rft_id=info:doi/10.1111%2Fj.1439-0272.2012.01324.x&rft.externalDBID=n%2Fa&rft.externalDocID=ark_67375_WNG_M9G26LF5_B |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0303-4569&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0303-4569&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0303-4569&client=summon |