KOBIO, the First Web-based Korean Biologics Registry Operated With a Unified Platform Among Distinct Disease Entities

The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012...

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Published inJournal of rheumatic diseases Vol. 28; no. 4; pp. 176 - 182
Main Authors Kim, Jinhyun, Koh, Jung Hee, Choi, Sung Jae, Jeon, Chan Hong, Kwok, Seung-Ki, Kim, Seong-Kyu, Choi, Chan-Bum, Lee, Jaejoon, Lee, Changhoon, Nam, Eon Jeong, Park, Yong-Beom, Lee, Shin-Seok, Kim, Tae-Hwan, Park, Sung-Hwan, Koh, Eun-Mi, Yoo, Dae-Hyun, Song, Yeong Wook, Kim, Hyoun-Ah, Shin, Kichul, Choe, Jung-Yoon
Format Journal Article
LanguageEnglish
Published Korea (South) Korean College of Rheumatology 01.10.2021
대한류마티스학회
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Online AccessGet full text
ISSN2093-940X
2233-4718
DOI10.4078/jrd.2021.28.4.176

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Abstract The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment.
AbstractList The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment. KCI Citation Count: 0
The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment.
Author Koh, Eun-Mi
Kim, Hyoun-Ah
Kwok, Seung-Ki
Kim, Seong-Kyu
Park, Yong-Beom
Park, Sung-Hwan
Kim, Jinhyun
Jeon, Chan Hong
Lee, Shin-Seok
Choi, Sung Jae
Yoo, Dae-Hyun
Lee, Changhoon
Kim, Tae-Hwan
Song, Yeong Wook
Choi, Chan-Bum
Koh, Jung Hee
Nam, Eon Jeong
Lee, Jaejoon
Shin, Kichul
Choe, Jung-Yoon
AuthorAffiliation 13 Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
15 Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea
1 Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea
10 Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
6 Division of Rheumatology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea
8 Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
12 Department of Rheumatology, Chonnam National University Hospital, Gwangju, Korea
2 Division of Rheumatology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
4 Division of Rheumatology, Department of Internal Medicine, Soonchunhyang
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Issue 4
Keywords Registries
Biological products
Rheumatoid arthritis
Ankylosing spondylitis
Psoriatic arthritis
Language English
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Title KOBIO, the First Web-based Korean Biologics Registry Operated With a Unified Platform Among Distinct Disease Entities
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