KOBIO, the First Web-based Korean Biologics Registry Operated With a Unified Platform Among Distinct Disease Entities
The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012...
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Published in | Journal of rheumatic diseases Vol. 28; no. 4; pp. 176 - 182 |
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Main Authors | , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Korea (South)
Korean College of Rheumatology
01.10.2021
대한류마티스학회 |
Subjects | |
Online Access | Get full text |
ISSN | 2093-940X 2233-4718 |
DOI | 10.4078/jrd.2021.28.4.176 |
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Abstract | The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment. |
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AbstractList | The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment. KCI Citation Count: 0 The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment. |
Author | Koh, Eun-Mi Kim, Hyoun-Ah Kwok, Seung-Ki Kim, Seong-Kyu Park, Yong-Beom Park, Sung-Hwan Kim, Jinhyun Jeon, Chan Hong Lee, Shin-Seok Choi, Sung Jae Yoo, Dae-Hyun Lee, Changhoon Kim, Tae-Hwan Song, Yeong Wook Choi, Chan-Bum Koh, Jung Hee Nam, Eon Jeong Lee, Jaejoon Shin, Kichul Choe, Jung-Yoon |
AuthorAffiliation | 13 Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea 15 Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea 1 Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea 10 Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea 6 Division of Rheumatology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea 8 Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea 12 Department of Rheumatology, Chonnam National University Hospital, Gwangju, Korea 2 Division of Rheumatology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea 4 Division of Rheumatology, Department of Internal Medicine, Soonchunhyang |
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Cites_doi | 10.1136/ard.2006.062760 10.1136/ard.62.suppl_2.ii28 10.1136/ard.2004.031476 10.55563/clinexprheumatol/z0va6o 10.1007/s40259-020-00432-z 10.1002/art.27227 10.1093/rheumatology/keab245 10.1007/s10067-021-05613-x 10.1136/ard.2008.091926 10.3899/jrheum.111125 10.1097/MD.0000000000019415 10.1002/pds.4932 10.1038/bjc.2013.725 10.1007/s10067-017-3584-y 10.1007/s40259-019-00393-y 10.1080/03009740510017968 10.1080/14397595.2016.1265637 10.1136/annrheumdis-2017-211623 10.1136/annrheumdis-2016-209285 10.1371/journal.pone.0205651 10.55563/clinexprheumatol/ftfgmf 10.1136/annrheumdis-2013-204102 10.1038/nrrheum.2017.81 10.1007/s10067-018-4290-0 10.1056/NEJMsb1609216 10.1097/RHU.0000000000001644 10.2165/00002018-200427080-00010 |
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Keywords | Registries Biological products Rheumatoid arthritis Ankylosing spondylitis Psoriatic arthritis |
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Title | KOBIO, the First Web-based Korean Biologics Registry Operated With a Unified Platform Among Distinct Disease Entities |
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