Risk Prediction Modeling on Family-Based Sequencing Data Using a Random Field Method - Wen, Yalu; Burt, Alexandra; Lu, Qing (Genetics (Austin), 2017)
Keywords: Accuracy; Breeding of animals; Cardiovascular disease; Computer simulation; Data processing; Design; Diabetes; Fields (mathematics); Genetic Heterogeneity; Genetic Predisposition to Disease; Genetics; Genome-Wide Association Study - methods; Genomes; Heterogeneity; Humans; Investigations; Mathematical models; Modelling; Models, Genetic; Mutation; Pedigree; Prediction models; Risk; Sequence Analysis, DNA - methods; Statistical methods; Stochastic processes; Studies; family-based studies; random field theory; high-dimensional data; genetic heterogeneity