Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome
Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consoli...
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| Published in | Tuberculosis and respiratory diseases Vol. 79; no. 4; pp. 302 - 306 |
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| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
The Korean Academy of Tuberculosis and Respiratory Diseases
01.10.2016
대한결핵및호흡기학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1738-3536 2005-6184 2005-6184 |
| DOI | 10.4046/trd.2016.79.4.302 |
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| Abstract | Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS. |
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| AbstractList | Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS. KCI Citation Count: 0 Systemic vasculitis involving the lung is a rare manifestation of myelodysplastic syndrome (MDS), and secondary vasculitis is considered to have poor prognosis. A 44-year-old man presented with fever and dyspnea of 1 month duration. A chest radiograph revealed bilateral multiple wedge shaped consolidations. In addition, the results of a percutaneous needle biopsy for non-resolving pneumonia were compatible with pulmonary vasculitis. Bone marrow biopsy was performed due to the persistence of unexplained anemia and the patient was diagnosed with MDS. We reported a case of secondary vasculitis presenting as non-resolving pneumonia, later diagnosed as paraneoplastic syndrome of undiagnosed MDS. The cytopenia and vasculitis improved after a short course of glucocorticoid treatment, and there was no recurrence despite the progression of underlying MDS. |
| Author | Chang, Sun Hee Jung, Hoon Yi, Seong Yoon Lee, Sung-Soon Won, Chang Youn Lee, Joo-Hyun Kim, Jae Hyung Park, Hye Kyeong Koo, Hyeon-Kyoung Lee, Seung Hyun Park, Sejin |
| AuthorAffiliation | 1 Department of Internal Medicine, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea 2 Department of Pathology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea |
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| Keywords | Myelodysplastic Syndromes Paraneoplastic Syndromes Pneumonia Vasculitis, Leukocytoclastic, Cutaneous |
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| Title | Pulmonary Leukocytoclastic Vasculitis as an Initial Presentation of Myelodysplastic Syndrome |
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