A multi-scale, mechanistic model of a wet granulation process using a novel bi-directional PBM–DEM coupling algorithm - Barrasso, Dana; Eppinger, Thomas; Pereira, Frances E.; Aglave, Ravindra; Debus, Kristian; Bermingham, Sean K.; Ramachandran, Rohit (Chemical engineering science, 2015)
Keywords: Algorithms; Binders; Discrete element method; Discrete element methods; Granular materials; Granulation; Mathematical models; Multi-scale modeling; Population balance modeling; Porosity; Process parameters; Quality-by-Design; Screws; Wet granulation; Wet granulation; Discrete element methods; Population balance modeling; Multi-scale modeling; Quality-by-Design