Bone Marrow Involvement of Epstein-Barr Virus-Positive Large B-Cell Lymphoma in a Patient with Angioimmunoblastic T-Cell Lymphoma

• Published in: Annals of laboratory medicine Vol. 38; no. 2; pp. 172 - 175
• Main Authors: Lee, Taegeun, Park, Borae G., You, Eunkyoung, Cho, Young-Uk, Jang, Seongsoo, Lee, Sun Mi, Suh, Cheolwon, Park, Chan-Jeoung
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society for Laboratory Medicine 01.03.2018; 대한진단검사의학회
• Subjects: Aged; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Bone Marrow - pathology; Bone Marrow - virology; Cyclophosphamide - therapeutic use; Doxorubicin - therapeutic use; Herpesvirus 4, Human - isolation & purification; Humans; Letter to the Editor; Lymph Nodes - diagnostic imaging; Lymph Nodes - pathology; Lymphoma, Large B-Cell, Diffuse - complications; Lymphoma, Large B-Cell, Diffuse - diagnosis; Lymphoma, Large B-Cell, Diffuse - drug therapy; Lymphoma, T-Cell - complications; Lymphoma, T-Cell - diagnosis; Lymphoma, T-Cell - drug therapy; Male; Prednisone - therapeutic use; Tomography, X-Ray Computed; Vincristine - therapeutic use; 병리학
• ISSN: 2234-3806; 2234-3814; 2234-3814
• DOI: 10.3343/alm.2018.38.2.172

Angioimmunoblastic T-cell lymphoma (AITL) is the second most common subtype of peripheral T-cell lymphoma, accounting for approximately 15–20% of the cases [1]. It is a systemic lymphoproliferative disorder that typically presents with constitutional symptoms, generalized lymphadenopathy, hepatosplenomegaly, skin rash, and immunological disturbances [2]. AITL may be accompanied by either polyclonal or clonal proliferation of B lymphocytes, which seems to be triggered by Epstein-Barr virus (EBV) infection [3]. KCI Citation Count: 0