Relationship between metabolic syndrome and thyroid nodules in healthy Koreans

This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 a...

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Published inThe Korean journal of internal medicine Vol. 31; no. 1; pp. 98 - 105
Main Authors Shin, Juyoung, Kim, Min-Hee, Yoon, Kun-Ho, Kang, Moo-Il, Cha, Bong-Yun, Lim, Dong-Jun
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Association of Internal Medicine 01.01.2016
대한내과학회
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Online AccessGet full text
ISSN1226-3303
2005-6648
2005-6648
DOI10.3904/kjim.2016.31.1.98

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Abstract This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 and June 2010; of these, 1,308 were excluded based upon predefined criteria. Among the remaining 1,990 patients, we examined the association between MS and its components and the incidence of thyroid nodules. Of the 1,990 subjects included in this study, 38.4% (n = 764) had thyroid nodules and 12.7% (n = 253) had MS. Female sex, older age, higher body mass index, larger waist circumference, higher glycated hemoglobin level, lower thyroid stimulating hormone level, and presence of MS were all closely related with the presence of thyroid nodules (all p < 0.05). Furthermore, the relevant number of MS components showed a positive linear correlation with the occurrence of thyroid nodules (p < 0.001). Evidence of MS alone was not independently associated with thyroid nodules after adjusting for sex and age in a multivariate binary logistic regression analysis; however, glycated hemoglobin for females and waist circumference for males, as well as both age and thyroid stimulating hormone for all patients, were identified as independent predictors for the existence of thyroid nodules (all p < 0.05). This study suggests a positive relationship between the components of MS and thyroid nodules in an ostensibly healthy Korean population. Our data support the idea that the recent increase in thyroid nodules is partly due to increases in both MS and obesity.
AbstractList This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 and June 2010; of these, 1,308 were excluded based upon predefined criteria. Among the remaining 1,990 patients, we examined the association between MS and its components and the incidence of thyroid nodules. Of the 1,990 subjects included in this study, 38.4% (n = 764) had thyroid nodules and 12.7% (n = 253) had MS. Female sex, older age, higher body mass index, larger waist circumference, higher glycated hemoglobin level, lower thyroid stimulating hormone level, and presence of MS were all closely related with the presence of thyroid nodules (all p < 0.05). Furthermore, the relevant number of MS components showed a positive linear correlation with the occurrence of thyroid nodules (p < 0.001). Evidence of MS alone was not independently associated with thyroid nodules after adjusting for sex and age in a multivariate binary logistic regression analysis; however, glycated hemoglobin for females and waist circumference for males, as well as both age and thyroid stimulating hormone for all patients, were identified as independent predictors for the existence of thyroid nodules (all p < 0.05). This study suggests a positive relationship between the components of MS and thyroid nodules in an ostensibly healthy Korean population. Our data support the idea that the recent increase in thyroid nodules is partly due to increases in both MS and obesity.
This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans.BACKGROUND/AIMSThis study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans.We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 and June 2010; of these, 1,308 were excluded based upon predefined criteria. Among the remaining 1,990 patients, we examined the association between MS and its components and the incidence of thyroid nodules.METHODSWe reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 and June 2010; of these, 1,308 were excluded based upon predefined criteria. Among the remaining 1,990 patients, we examined the association between MS and its components and the incidence of thyroid nodules.Of the 1,990 subjects included in this study, 38.4% (n = 764) had thyroid nodules and 12.7% (n = 253) had MS. Female sex, older age, higher body mass index, larger waist circumference, higher glycated hemoglobin level, lower thyroid stimulating hormone level, and presence of MS were all closely related with the presence of thyroid nodules (all p < 0.05). Furthermore, the relevant number of MS components showed a positive linear correlation with the occurrence of thyroid nodules (p < 0.001). Evidence of MS alone was not independently associated with thyroid nodules after adjusting for sex and age in a multivariate binary logistic regression analysis; however, glycated hemoglobin for females and waist circumference for males, as well as both age and thyroid stimulating hormone for all patients, were identified as independent predictors for the existence of thyroid nodules (all p < 0.05).RESULTSOf the 1,990 subjects included in this study, 38.4% (n = 764) had thyroid nodules and 12.7% (n = 253) had MS. Female sex, older age, higher body mass index, larger waist circumference, higher glycated hemoglobin level, lower thyroid stimulating hormone level, and presence of MS were all closely related with the presence of thyroid nodules (all p < 0.05). Furthermore, the relevant number of MS components showed a positive linear correlation with the occurrence of thyroid nodules (p < 0.001). Evidence of MS alone was not independently associated with thyroid nodules after adjusting for sex and age in a multivariate binary logistic regression analysis; however, glycated hemoglobin for females and waist circumference for males, as well as both age and thyroid stimulating hormone for all patients, were identified as independent predictors for the existence of thyroid nodules (all p < 0.05).This study suggests a positive relationship between the components of MS and thyroid nodules in an ostensibly healthy Korean population. Our data support the idea that the recent increase in thyroid nodules is partly due to increases in both MS and obesity.CONCLUSIONSThis study suggests a positive relationship between the components of MS and thyroid nodules in an ostensibly healthy Korean population. Our data support the idea that the recent increase in thyroid nodules is partly due to increases in both MS and obesity.
Background/Aims: This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. Methods: We reviewed the records of 3,298 subjects with no noticeable symptoms who underwent thyroid ultrasound imaging as part of a routine check-up between July 2009 and June 2010; of these, 1,308 were excluded based upon predefined criteria. Among the remaining 1,990 patients, we examined the association between MS and its components and the incidence of thyroid nodules. Results: Of the 1,990 subjects included in this study, 38.4% (n = 764) had thyroid nodules and 12.7% (n = 253) had MS. Female sex, older age, higher body mass index, larger waist circumference, higher glycated hemoglobin level, lower thyroid stimulating hormone level, and presence of MS were all closely related with the presence of thyroid nodules (all p < 0.05). Furthermore, the relevant number of MS components showed a positive linear correlation with the occurrence of thyroid nodules (p < 0.001). Evidence of MS alone was not independently associated with thyroid nodules after adjusting for sex and age in a multivariate binary logistic regression analysis; however, glycated hemoglobin for females and waist circumference for males, as well as both age and thyroid stimulating hormone for all patients, were identified as independent predictors for the existence of thyroid nodules (all p < 0.05). Conclusions: This study suggests a positive relationship between the components of MS and thyroid nodules in an ostensibly healthy Korean population. Our data support the idea that the recent increase in thyroid nodules is partly due to increases in both MS and obesity. KCI Citation Count: 15
Author Cha, Bong-Yun
Shin, Juyoung
Kim, Min-Hee
Yoon, Kun-Ho
Kang, Moo-Il
Lim, Dong-Jun
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Cites_doi 10.1016/j.ejca.2007.11.005
10.1002/ijc.1377
10.1038/nrc1408
10.1097/TEN.0b013e3181fd02f2
10.1111/j.1464-5491.2004.01149.x
10.1097/GME.0b013e31828ce95d
10.1016/j.ghir.2004.01.005
10.1530/EJE-09-0410
10.1210/jc.2007-2174
10.1038/sj.bjc.6603249
10.1023/A:1008938520101
10.2337/dc10-2109
10.1111/j.1464-5491.2007.02106.x
10.1158/1055-9965.EPI-08-0960
10.1093/aje/kwg100
10.1016/S0140-6736(05)66378-7
10.1089/met.2008.0065
10.1089/met.2008.0062
10.1093/aje/kwj284
10.2337/dc06-1414
10.3904/kjim.2013.28.2.180
10.1007/s12032-009-9189-9
10.4174/jkss.2012.82.1.13
10.1136/pgmj.66.773.186
10.1001/jama.295.18.2164
10.1001/archinte.163.11.1306
10.4093/dmj.2011.35.5.431
10.1002/ijc.26161
10.1155/2014/675796
10.3349/ymj.2000.41.1.22
10.1186/1471-2458-7-220
10.1210/jc.2014-2723
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Issue 1
Keywords Thyroid nodule
Metabolic syndrome
Obesity
Language English
License This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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A portion of these results were presented in abstract form at the 2013 Seoul International Congress of Endocrinology and Metabolism in Seoul, Korea.
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References ref13
ref35
ref12
ref34
ref15
ref36
ref31
ref30
ref33
ref10
ref32
ref2
ref1
Tulinius (ref14) 1997
ref17
ref16
ref19
ref18
(ref28) 2009
ref24
ref23
ref26
ref25
Mazzaferri (ref20) 1993
ref22
ref21
ref27
ref29
ref8
ref7
(ref11) 2001
ref9
ref4
ref3
ref6
ref5
19263254 - Med Oncol. 2010 Jun;27(2):177-84
19284314 - Metab Syndr Relat Disord. 2009 Aug;7(4):279-88
9367058 - Cancer Epidemiol Biomarkers Prev. 1997 Nov;6(11):863-73
10710197 - Cancer Causes Control. 2000 Feb;11(2):137-44
8426623 - N Engl J Med. 1993 Feb 25;328(8):553-9
2114018 - Postgrad Med J. 1990 Mar;66(773):186-90
18460560 - J Clin Endocrinol Metab. 2008 Jul;93(7):2447-53
16684987 - JAMA. 2006 May 10;295(18):2164-7
16832414 - Br J Cancer. 2006 Aug 7;95(3):366-70
22111032 - Diabetes Metab J. 2011 Oct;35(5):431-6
11368702 - JAMA. 2001 May 16;285(19):2486-97
11477590 - Int J Cancer. 2001 Sep 1;93(5):745-50
19502545 - Diabetes Care. 2009 Jul;32(7):1327-34
25197276 - Int J Endocrinol. 2014;2014:675796
25368977 - J Clin Endocrinol Metab. 2015 Jan;100(1):184-92
15008828 - Diabet Med. 2004 Mar;21(3):208-13
16952929 - Am J Epidemiol. 2006 Oct 15;164(8):769-74
19240234 - Cancer Epidemiol Biomarkers Prev. 2009 Mar;18(3):784-91
12796045 - Am J Epidemiol. 2003 Jun 15;157(12):1092-100
22324041 - J Korean Surg Soc. 2012 Jan;82(1):13-7
23571527 - Menopause. 2013 Dec;20(12):1301-9
21544808 - Int J Cancer. 2012 Mar 15;130(6):1411-9
23525791 - Korean J Intern Med. 2013 Mar;28(2):180-6
21505206 - Diabetes Care. 2011 Jun;34(6):1323-8
15286738 - Nat Rev Cancer. 2004 Aug;4(8):579-91
19320560 - Metab Syndr Relat Disord. 2009 Aug;7(4):375-80
17727697 - BMC Public Health. 2007;7:220
15836891 - Lancet. 2005 Apr 16-22;365(9468):1415-28
17367307 - Diabet Med. 2007 Apr;24(4):333-43
10731915 - Yonsei Med J. 2000 Feb;41(1):22-8
17192325 - Diabetes Care. 2007 Jan;30(1):8-13
15143963 - Tumori. 2004 Jan-Feb;90(1):9-12
19633072 - Eur J Endocrinol. 2009 Oct;161(4):599-605
18055193 - Eur J Cancer. 2008 Jan;44(2):293-7
15231294 - Growth Horm IGF Res. 2004 Aug;14(4):261-9
12796066 - Arch Intern Med. 2003 Jun 9;163(11):1306-16
References_xml – ident: ref7
  doi: 10.1016/j.ejca.2007.11.005
– ident: ref17
  doi: 10.1002/ijc.1377
– start-page: 2486
  volume-title: Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
  year: 2001
  ident: ref11
– ident: ref15
  doi: 10.1038/nrc1408
– start-page: 863
  volume-title: Risk factors for malignant diseases: a cohort study on a population of 22,946 Icelanders
  year: 1997
  ident: ref14
– ident: ref24
  doi: 10.1097/TEN.0b013e3181fd02f2
– ident: ref26
  doi: 10.1111/j.1464-5491.2004.01149.x
– ident: ref6
  doi: 10.1097/GME.0b013e31828ce95d
– ident: ref16
  doi: 10.1016/j.ghir.2004.01.005
– ident: ref9
  doi: 10.1530/EJE-09-0410
– ident: ref29
  doi: 10.1210/jc.2007-2174
– ident: ref32
  doi: 10.1038/sj.bjc.6603249
– ident: ref31
  doi: 10.1023/A:1008938520101
– ident: ref36
  doi: 10.2337/dc10-2109
– ident: ref30
  doi: 10.1111/j.1464-5491.2007.02106.x
– ident: ref2
  doi: 10.1158/1055-9965.EPI-08-0960
– ident: ref13
  doi: 10.1093/aje/kwg100
– start-page: 553
  volume-title: Management of a solitary thyroid nodule
  year: 1993
  ident: ref20
– ident: ref3
  doi: 10.1016/S0140-6736(05)66378-7
– start-page: 1327
  volume-title: International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes
  year: 2009
  ident: ref28
– ident: ref5
  doi: 10.1089/met.2008.0065
– ident: ref10
  doi: 10.1089/met.2008.0062
– ident: ref8
  doi: 10.1093/aje/kwj284
– ident: ref4
  doi: 10.2337/dc06-1414
– ident: ref35
  doi: 10.3904/kjim.2013.28.2.180
– ident: ref23
  doi: 10.1007/s12032-009-9189-9
– ident: ref21
  doi: 10.4174/jkss.2012.82.1.13
– ident: ref34
  doi: 10.1136/pgmj.66.773.186
– ident: ref1
  doi: 10.1001/jama.295.18.2164
– ident: ref25
  doi: 10.1001/archinte.163.11.1306
– ident: ref27
  doi: 10.4093/dmj.2011.35.5.431
– ident: ref33
  doi: 10.1002/ijc.26161
– ident: ref18
  doi: 10.1155/2014/675796
– ident: ref12
  doi: 10.3349/ymj.2000.41.1.22
– ident: ref22
  doi: 10.1186/1471-2458-7-220
– ident: ref19
  doi: 10.1210/jc.2014-2723
– reference: 25197276 - Int J Endocrinol. 2014;2014:675796
– reference: 21544808 - Int J Cancer. 2012 Mar 15;130(6):1411-9
– reference: 22324041 - J Korean Surg Soc. 2012 Jan;82(1):13-7
– reference: 17192325 - Diabetes Care. 2007 Jan;30(1):8-13
– reference: 9367058 - Cancer Epidemiol Biomarkers Prev. 1997 Nov;6(11):863-73
– reference: 23571527 - Menopause. 2013 Dec;20(12):1301-9
– reference: 18460560 - J Clin Endocrinol Metab. 2008 Jul;93(7):2447-53
– reference: 15143963 - Tumori. 2004 Jan-Feb;90(1):9-12
– reference: 19263254 - Med Oncol. 2010 Jun;27(2):177-84
– reference: 25368977 - J Clin Endocrinol Metab. 2015 Jan;100(1):184-92
– reference: 11477590 - Int J Cancer. 2001 Sep 1;93(5):745-50
– reference: 17727697 - BMC Public Health. 2007;7:220
– reference: 19240234 - Cancer Epidemiol Biomarkers Prev. 2009 Mar;18(3):784-91
– reference: 11368702 - JAMA. 2001 May 16;285(19):2486-97
– reference: 19633072 - Eur J Endocrinol. 2009 Oct;161(4):599-605
– reference: 22111032 - Diabetes Metab J. 2011 Oct;35(5):431-6
– reference: 15008828 - Diabet Med. 2004 Mar;21(3):208-13
– reference: 16684987 - JAMA. 2006 May 10;295(18):2164-7
– reference: 8426623 - N Engl J Med. 1993 Feb 25;328(8):553-9
– reference: 16832414 - Br J Cancer. 2006 Aug 7;95(3):366-70
– reference: 17367307 - Diabet Med. 2007 Apr;24(4):333-43
– reference: 18055193 - Eur J Cancer. 2008 Jan;44(2):293-7
– reference: 19284314 - Metab Syndr Relat Disord. 2009 Aug;7(4):279-88
– reference: 12796066 - Arch Intern Med. 2003 Jun 9;163(11):1306-16
– reference: 2114018 - Postgrad Med J. 1990 Mar;66(773):186-90
– reference: 10710197 - Cancer Causes Control. 2000 Feb;11(2):137-44
– reference: 19320560 - Metab Syndr Relat Disord. 2009 Aug;7(4):375-80
– reference: 15286738 - Nat Rev Cancer. 2004 Aug;4(8):579-91
– reference: 12796045 - Am J Epidemiol. 2003 Jun 15;157(12):1092-100
– reference: 23525791 - Korean J Intern Med. 2013 Mar;28(2):180-6
– reference: 16952929 - Am J Epidemiol. 2006 Oct 15;164(8):769-74
– reference: 19502545 - Diabetes Care. 2009 Jul;32(7):1327-34
– reference: 21505206 - Diabetes Care. 2011 Jun;34(6):1323-8
– reference: 15836891 - Lancet. 2005 Apr 16-22;365(9468):1415-28
– reference: 15231294 - Growth Horm IGF Res. 2004 Aug;14(4):261-9
– reference: 10731915 - Yonsei Med J. 2000 Feb;41(1):22-8
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Snippet This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. We reviewed the...
This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans.BACKGROUND/AIMSThis...
Background/Aims: This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans....
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StartPage 98
SubjectTerms Adult
Biomarkers - blood
Body Mass Index
Chi-Square Distribution
Cross-Sectional Studies
Diabetes Mellitus - diagnosis
Diabetes Mellitus - epidemiology
Female
Glycated Hemoglobin A - analysis
Humans
Incidence
Linear Models
Logistic Models
Male
Metabolic Syndrome - blood
Metabolic Syndrome - diagnosis
Metabolic Syndrome - epidemiology
Middle Aged
Multivariate Analysis
Obesity - diagnosis
Obesity - epidemiology
Odds Ratio
Original
Republic of Korea - epidemiology
Retrospective Studies
Risk Factors
Thyroid Nodule - blood
Thyroid Nodule - diagnostic imaging
Thyroid Nodule - epidemiology
Thyrotropin - blood
Waist Circumference
내과학
Title Relationship between metabolic syndrome and thyroid nodules in healthy Koreans
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