Sportology: An Innovative, Interdisciplinary Scientific Wisdom

We proposed a new wisdom called sportology, a scientific approach to the relationship between sports and health. Needless to say, well-trained, non-stressful physical activities are expected to be the most important methods to comprehensively reduce various health problems. While using “sports” and...

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Published inJuntendo Iji Zasshi = Juntendo Medical Journal Vol. 66; no. Suppl.1; pp. 3 - 12
Main Author KAWAMORI, RYUZO
Format Journal Article
LanguageEnglish
Published The Juntendo Medical Society 2020
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Online AccessGet full text
ISSN2187-9737
2188-2126
DOI10.14789/jmj.2020.66.JMJ19-P07

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Abstract We proposed a new wisdom called sportology, a scientific approach to the relationship between sports and health. Needless to say, well-trained, non-stressful physical activities are expected to be the most important methods to comprehensively reduce various health problems. While using “sports” and “health” as keywords to deepen the respective specialized sciences involved, sportology simultaneously integrates each of these specializations, creating opportunities where deepening and integration are possible and giving society more effective and efficient academic achievements. In 2007, Juntendo University, with the aid of the Ministry of Education, Culture, Sports, Science, and Technology of Japan, established the Sportology Center, where our motto is to “measure precisely whatever we can measure and make measurable what is not measured in human beings.” Our aim for this center is to translate what we have found at the molecular, cell, and animal levels into demonstrable in human beings. With new findings obtained at this center, we will be able to develop new biomarkers and bioimaging techniques with which we will be able to perform more precise diagnosis and treatment. Among numerous new findings obtained by the Sportology Center, some topics are highlighted.
AbstractList We proposed a new wisdom called sportology, a scientific approach to the relationship between sports and health. Needless to say, well-trained, non-stressful physical activities are expected to be the most important methods to comprehensively reduce various health problems. While using “sports” and “health” as keywords to deepen the respective specialized sciences involved, sportology simultaneously integrates each of these specializations, creating opportunities where deepening and integration are possible and giving society more effective and efficient academic achievements. In 2007, Juntendo University, with the aid of the Ministry of Education, Culture, Sports, Science, and Technology of Japan, established the Sportology Center, where our motto is to “measure precisely whatever we can measure and make measurable what is not measured in human beings.” Our aim for this center is to translate what we have found at the molecular, cell, and animal levels into demonstrable in human beings. With new findings obtained at this center, we will be able to develop new biomarkers and bioimaging techniques with which we will be able to perform more precise diagnosis and treatment. Among numerous new findings obtained by the Sportology Center, some topics are highlighted.
Author KAWAMORI, RYUZO
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Cites_doi 10.1210/jc.2016-1650
10.1016/j.joca.2015.05.017
10.1210/jc.2006-2384
10.14789/jmj.62.s166
10.1007/s13340-018-0345-3
10.1172/JCI108645
10.1210/js.2017-00418
10.1136/bmjopen-2019-031584
10.1016/j.joca.2014.07.021
10.1210/jc.2018-02190
10.1016/j.joca.2013.05.014
10.2169/internalmedicine.54.3024
10.1172/JCI108275
10.14789/pjmj.56.239
10.1210/jc.2004-1959
10.1186/s13075-017-1411-0
10.2337/dc19-S016
10.1007/s00380-016-0844-8
10.1371/journal.pone.0061604
10.1016/j.matbio.2013.01.004
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20) Kaneko H, Ishijima M, Futami I, et al: Synovial perlecan is required for osteophyte formation in knee osteoarthritis. Matrix Biol, 2013; 32: 178-187.
4) Cosentino F, Grant PJ, Aboyans V, et al; ESC Scientific Document Group: 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. Eur Heart J, 2020; 41: 255-323.
17) Sai E, Shimada K, Yokoyama T, et al: Myocardial triglyceride content in patients with left ventricular hypertrophy: comparison between hypertensive heart disease and hypertrophic cardiomyopathy. Heart Vessels, 2017; 32: 166-174.
18) Shimura Y, Kurosawa H, Sugawara Y, et al: The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: A cross-sectional study. Osteoarthritis Cartilage, 2013; 21: 1179-1184.
14) Someya Y, Tamura Y, Kaga H, et al: Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study. BMJ Open, 2019; 9: e031584.
1) Kawamori R, Vranic M: Mechanism of exercise-induced hypoglycemia in depancreatized dogs maintained on long-acting insulin. J Clin Invest, 1977; 59: 331-337.
12) Sugimoto D, Tamura Y, Takeno K, et al: Clinical features of nonobese, apparently healthy, Japanese men with reduced adipose tissue insulin sensitivity. J Clin Endocrinol Metab, 2019; 104: 2325-2333.
2) Vranic M, Kawamori R, Pek S, et al: The essentiality of insulin and the role of glucagon in regulating glucose utilization and production during strenuous exercise in dogs. J Clin Invest, 1976; 57: 245-255.
10) Sato F, Tamura Y, Watada H, et al: Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects. J Clin Endocrinol Metab, 2007; 92: 3326-3329.
5) American diabetes Association: Standards of Medical Care in Diabetes─2019. Diabetes Care, 2019; 42 (Suppl. 1).
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8) Juntendo Medical Journal, 2018; 64 (Suppl. 1).
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19) Yusup A, Kaneko H, Liu L, et al: Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee osteoarthritis: A cross-sectional study. Osteoarthritis Cartilage, 2015; 23: 1858-1864.
9) Tamura Y, Tanaka Y, Sato F, et al: Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab, 2005; 90: 3191-3196.
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13) Someya Y, Tamura Y, Suzuki R, et al: Characteristics of glucose metabolism in underweight Japanese women. J Endocr Soc, 2018; 2: 279-289.
3) Haneda M, Noda M, Origasa H, et al: Japanese clinical practice guideline for Diabetes 2016. Diabet Interna, 2018; 9: 1-45.
7) Juntendo Medical Journal, 2016; 62 (Suppl. 1).
22) Hada S, Ishijima M, Kaneko H, et al: Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in the patients with early-stage knee osteoarthritis. Arthritis Res Ther, 2017; 19: 201.
11
22
12
13
14
15
16
17
18
19
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2
3
4
5
6
7
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References_xml – reference: 15) Sai E, Shimada K, Yokoyama T, et al: Evaluation of myocardial triglyceride accumulation assessed on 1 H-magnetic resonance spectroscopy in apparently healthy Japanese subjects. Intern Med, 2015; 54: 367-373.
– reference: 14) Someya Y, Tamura Y, Kaga H, et al: Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study. BMJ Open, 2019; 9: e031584.
– reference: 19) Yusup A, Kaneko H, Liu L, et al: Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee osteoarthritis: A cross-sectional study. Osteoarthritis Cartilage, 2015; 23: 1858-1864.
– reference: 18) Shimura Y, Kurosawa H, Sugawara Y, et al: The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: A cross-sectional study. Osteoarthritis Cartilage, 2013; 21: 1179-1184.
– reference: 17) Sai E, Shimada K, Yokoyama T, et al: Myocardial triglyceride content in patients with left ventricular hypertrophy: comparison between hypertensive heart disease and hypertrophic cardiomyopathy. Heart Vessels, 2017; 32: 166-174.
– reference: 11) Takeno K, Tamura Y, Kawaguchi M, et al: Relation between insulin sensitivity and metabolic abnormalities in Japanese men with BMI of 23-25 kg/m2. J Clin Endocrinol Metab, 2016; 101: 3676-3684.
– reference: 5) American diabetes Association: Standards of Medical Care in Diabetes─2019. Diabetes Care, 2019; 42 (Suppl. 1).
– reference: 9) Tamura Y, Tanaka Y, Sato F, et al: Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab, 2005; 90: 3191-3196.
– reference: 3) Haneda M, Noda M, Origasa H, et al: Japanese clinical practice guideline for Diabetes 2016. Diabet Interna, 2018; 9: 1-45.
– reference: 16) Sai E, Shimada K, Yokoyama T, et al: Association between myocardial triglyceride content and cardiac function in healthy subjects and endurance athletes. PLoS One, 2013; 8: e61604.
– reference: 4) Cosentino F, Grant PJ, Aboyans V, et al; ESC Scientific Document Group: 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. Eur Heart J, 2020; 41: 255-323.
– reference: 6) Kawamori R: Sportology for the prevention and treatment of diabetes mellitus. Juntendo Medical Journal, 2010; 56: 239-242.
– reference: 22) Hada S, Ishijima M, Kaneko H, et al: Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in the patients with early-stage knee osteoarthritis. Arthritis Res Ther, 2017; 19: 201.
– reference: 10) Sato F, Tamura Y, Watada H, et al: Effects of diet-induced moderate weight reduction on intrahepatic and intramyocellular triglycerides and glucose metabolism in obese subjects. J Clin Endocrinol Metab, 2007; 92: 3326-3329.
– reference: 12) Sugimoto D, Tamura Y, Takeno K, et al: Clinical features of nonobese, apparently healthy, Japanese men with reduced adipose tissue insulin sensitivity. J Clin Endocrinol Metab, 2019; 104: 2325-2333.
– reference: 20) Kaneko H, Ishijima M, Futami I, et al: Synovial perlecan is required for osteophyte formation in knee osteoarthritis. Matrix Biol, 2013; 32: 178-187.
– reference: 21) Hada S, Kaneko H, Sadatsuki R, et al: The degeneration and destruction of femoral articular cartilage shows a greater degree of deterioration than that of the tibial and patellar articular cartilage in early stage knee osteoarthritis: A cross-sectional study. Osteoarthritis Cartilage, 2014; 22: 1583-1589.
– reference: 7) Juntendo Medical Journal, 2016; 62 (Suppl. 1).
– reference: 8) Juntendo Medical Journal, 2018; 64 (Suppl. 1).
– reference: 1) Kawamori R, Vranic M: Mechanism of exercise-induced hypoglycemia in depancreatized dogs maintained on long-acting insulin. J Clin Invest, 1977; 59: 331-337.
– reference: 2) Vranic M, Kawamori R, Pek S, et al: The essentiality of insulin and the role of glucagon in regulating glucose utilization and production during strenuous exercise in dogs. J Clin Invest, 1976; 57: 245-255.
– reference: 13) Someya Y, Tamura Y, Suzuki R, et al: Characteristics of glucose metabolism in underweight Japanese women. J Endocr Soc, 2018; 2: 279-289.
– ident: 11
  doi: 10.1210/jc.2016-1650
– ident: 19
  doi: 10.1016/j.joca.2015.05.017
– ident: 10
  doi: 10.1210/jc.2006-2384
– ident: 4
– ident: 7
  doi: 10.14789/jmj.62.s166
– ident: 3
  doi: 10.1007/s13340-018-0345-3
– ident: 1
  doi: 10.1172/JCI108645
– ident: 13
  doi: 10.1210/js.2017-00418
– ident: 14
  doi: 10.1136/bmjopen-2019-031584
– ident: 21
  doi: 10.1016/j.joca.2014.07.021
– ident: 12
  doi: 10.1210/jc.2018-02190
– ident: 18
  doi: 10.1016/j.joca.2013.05.014
– ident: 15
  doi: 10.2169/internalmedicine.54.3024
– ident: 2
  doi: 10.1172/JCI108275
– ident: 6
  doi: 10.14789/pjmj.56.239
– ident: 9
  doi: 10.1210/jc.2004-1959
– ident: 22
  doi: 10.1186/s13075-017-1411-0
– ident: 5
  doi: 10.2337/dc19-S016
– ident: 8
– ident: 17
  doi: 10.1007/s00380-016-0844-8
– ident: 16
  doi: 10.1371/journal.pone.0061604
– ident: 20
  doi: 10.1016/j.matbio.2013.01.004
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Snippet We proposed a new wisdom called sportology, a scientific approach to the relationship between sports and health. Needless to say, well-trained, non-stressful...
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SubjectTerms glucose spillover
knee osteoarthritis
lipid spillover
physical inactivity
sportology
Title Sportology: An Innovative, Interdisciplinary Scientific Wisdom
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