Protein Phosphatase 2A Reduces Cigarette Smoke–induced Cathepsin S and Loss of Lung Function - Doherty, Declan F.; Nath, Sridesh; Poon, Justin; Foronjy, Robert F.; Ohlmeyer, Michael; Dabo, Abdoulaye J.; Salathe, Matthias; Birrell, Mark; Belvisi, Maria; Baumlin, Nathalie; Kim, Michael D.; Weldon, Sinéad; et al. (American journal of respiratory and critical care medicine, 2019)
Keywords: Animals; Bronchi - cytology; Cancer; Case-Control Studies; Cathepsins - metabolism; Chronic obstructive pulmonary disease; Cigarette Smoking - adverse effects; Cigarette Smoking - metabolism; Cigarettes; Critical care; Disease; Disease Models, Animal; Enzyme Inhibitors - pharmacology; Enzymes; Gene Silencing; Humans; Laboratory animals; Lung - drug effects; Lung - metabolism; Lungs; Lupus; Macrophages, Alveolar - metabolism; Medicine; Mice; Mice, Knockout; Nicotiana; Okadaic Acid - pharmacology; Original; Pathogenesis; Phosphatase; Protein Phosphatase 2 - antagonists & inhibitors; Protein Phosphatase 2 - metabolism; Proteins; Pulmonary Disease, Chronic Obstructive - etiology; Pulmonary Disease, Chronic Obstructive - metabolism; Pulmonary Disease, Chronic Obstructive - physiopathology; Respiratory Mucosa - cytology; Smoke - adverse effects; Tobacco smoke; United Kingdom--UK; New York; phosphatase; cigarette smoke; cathepsin S; chronic obstructive pulmonary disease