The building of an institutional liver transplant registry: opportunities and challenges
To improve current data systems for institutional decision-making, the Adult Liver Transplant Registry was established at the Hospital Italiano de Buenos Aires, Argentina. This article describes its design and implementation and reports on the outcomes for patients transplanted since its January 202...
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| Published in | Journal of international medical research Vol. 52; no. 7; p. 3000605241264232 |
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| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
London, England
SAGE Publications
01.07.2024
Sage Publications Ltd SAGE Publishing |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0300-0605 1473-2300 1473-2300 |
| DOI | 10.1177/03000605241264232 |
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| Abstract | To improve current data systems for institutional decision-making, the Adult Liver Transplant Registry was established at the Hospital Italiano de Buenos Aires, Argentina. This article describes its design and implementation and reports on the outcomes for patients transplanted since its January 2020 launch. A multidisciplinary team designed the registry by identifying key variables from a literature review while considering balance between data depth and feasibility. Rigorous quality control measures were enforced, including monthly audits and staff training. Benchmark indicators for post-transplant outcomes were established. As of November 2023, the registry included 136 transplants. Its implementation and maintenance were straightforward, with no significant difficulties encountered. Cirrhosis was the predominant indication (77%) for transplant. Only one living donor transplantation was performed. Post-transplant results generally aligned with benchmarks, but rates of biliary complications slightly exceeded the recommended thresholds. The one-year post-transplant survival rate was 87%. The successful registry implementation provides a robust framework for research, treatment management, and patient care enhancement within a liver transplant unit. |
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| AbstractList | To improve current data systems for institutional decision-making, the Adult Liver Transplant Registry was established at the Hospital Italiano de Buenos Aires, Argentina. This article describes its design and implementation and reports on the outcomes for patients transplanted since its January 2020 launch. A multidisciplinary team designed the registry by identifying key variables from a literature review while considering balance between data depth and feasibility. Rigorous quality control measures were enforced, including monthly audits and staff training. Benchmark indicators for post-transplant outcomes were established. As of November 2023, the registry included 136 transplants. Its implementation and maintenance were straightforward, with no significant difficulties encountered. Cirrhosis was the predominant indication (77%) for transplant. Only one living donor transplantation was performed. Post-transplant results generally aligned with benchmarks, but rates of biliary complications slightly exceeded the recommended thresholds. The one-year post-transplant survival rate was 87%. The successful registry implementation provides a robust framework for research, treatment management, and patient care enhancement within a liver transplant unit. To improve current data systems for institutional decision-making, the Adult Liver Transplant Registry was established at the Hospital Italiano de Buenos Aires, Argentina. This article describes its design and implementation and reports on the outcomes for patients transplanted since its January 2020 launch. A multidisciplinary team designed the registry by identifying key variables from a literature review while considering balance between data depth and feasibility. Rigorous quality control measures were enforced, including monthly audits and staff training. Benchmark indicators for post-transplant outcomes were established. As of November 2023, the registry included 136 transplants. Its implementation and maintenance were straightforward, with no significant difficulties encountered. Cirrhosis was the predominant indication (77%) for transplant. Only one living donor transplantation was performed. Post-transplant results generally aligned with benchmarks, but rates of biliary complications slightly exceeded the recommended thresholds. The one-year post-transplant survival rate was 87%. The successful registry implementation provides a robust framework for research, treatment management, and patient care enhancement within a liver transplant unit.To improve current data systems for institutional decision-making, the Adult Liver Transplant Registry was established at the Hospital Italiano de Buenos Aires, Argentina. This article describes its design and implementation and reports on the outcomes for patients transplanted since its January 2020 launch. A multidisciplinary team designed the registry by identifying key variables from a literature review while considering balance between data depth and feasibility. Rigorous quality control measures were enforced, including monthly audits and staff training. Benchmark indicators for post-transplant outcomes were established. As of November 2023, the registry included 136 transplants. Its implementation and maintenance were straightforward, with no significant difficulties encountered. Cirrhosis was the predominant indication (77%) for transplant. Only one living donor transplantation was performed. Post-transplant results generally aligned with benchmarks, but rates of biliary complications slightly exceeded the recommended thresholds. The one-year post-transplant survival rate was 87%. The successful registry implementation provides a robust framework for research, treatment management, and patient care enhancement within a liver transplant unit. |
| Author | Martínez Morales, Jorge Carlos de Santibañes, Eduardo de Santibañes, Martin Juana, Camila Marciano, Sebastián Ardiles, Victoria Uño Tala, Jimmy Walker Pekolj, Juan Burgos Pratx, Leandro Daniel Francisconi, Mariela Gadano, Adrian |
| Author_xml | – sequence: 1 givenname: Sebastián orcidid: 0000-0002-7983-1450 surname: Marciano fullname: Marciano, Sebastián email: sebastian.marciano@hospitalitaliano.org.ar organization: Hospital Italiano de Buenos Aires, Research Department, Buenos Aires, Argentina – sequence: 2 givenname: Jorge Carlos surname: Martínez Morales fullname: Martínez Morales, Jorge Carlos organization: Hospital Italiano de Buenos Aires, Liver Unit, Buenos Aires, Argentina – sequence: 3 givenname: Camila surname: Juana fullname: Juana, Camila organization: Instituto Universitario del Hospital Italiano de Buenos Aires, School of Medicine, Buenos Aires, Argentina – sequence: 4 givenname: Martin surname: de Santibañes fullname: de Santibañes, Martin organization: Instituto Universitario del Hospital Italiano de Buenos Aires, General Surgery Department, Buenos Aires, Argentina – sequence: 5 givenname: Juan surname: Pekolj fullname: Pekolj, Juan organization: Hospital Italiano de Buenos Aires, General Surgery Service and Liver Transplant Unit, Buenos Aires, Argentina – sequence: 6 givenname: Eduardo surname: de Santibañes fullname: de Santibañes, Eduardo organization: Instituto Universitario del Hospital Italiano de Buenos Aires, General Surgery Department, Buenos Aires, Argentina – sequence: 7 givenname: Mariela surname: Francisconi fullname: Francisconi, Mariela organization: Hospital Italiano de Buenos Aires, Liver Unit, Buenos Aires, Argentina – sequence: 8 givenname: Jimmy Walker surname: Uño Tala fullname: Uño Tala, Jimmy Walker organization: Hospital Italiano de Buenos Aires, General Surgery Service and Liver Transplant Unit, Buenos Aires, Argentina – sequence: 9 givenname: Leandro Daniel surname: Burgos Pratx fullname: Burgos Pratx, Leandro Daniel organization: Hospital Italiano de Buenos Aires, Transfusional Medicine Department, Buenos Aires, Argentina – sequence: 10 givenname: Adrian surname: Gadano fullname: Gadano, Adrian organization: Hospital Italiano de Buenos Aires, Research Department, Buenos Aires, Argentina – sequence: 11 givenname: Victoria surname: Ardiles fullname: Ardiles, Victoria organization: Instituto Universitario del Hospital Italiano de Buenos Aires, General Surgery Department, Buenos Aires, Argentina |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39079129$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Adult Aged Argentina - epidemiology Female Humans Liver Transplantation - methods Liver transplants Male Middle Aged Registries Survival Rate |
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| Title | The building of an institutional liver transplant registry: opportunities and challenges |
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