Anfibatide protects against rat cerebral ischemia/reperfusion injury via TLR4/JNK/caspase-3 pathway - Luo, Sheng-Yong; Li, Rui; Le, Zhi-Yong; Li, Qing-Lin; Chen, Zhi-Wu (European journal of pharmacology, 2017)
Keywords: Afibatide; Animals; Antigens, Nuclear - metabolism; Apoptosis; Apoptosis - drug effects; Caspase 3 - metabolism; Crotalid Venoms - pharmacology; Cytoprotection - drug effects; Enzyme Activation - drug effects; Gene Expression Regulation - drug effects; Hippocampus - drug effects; Hippocampus - metabolism; Hippocampus - pathology; Hippocampus - physiopathology; Infarction, Middle Cerebral Artery - complications; Inflammation Mediators - metabolism; JNK Mitogen-Activated Protein Kinases - metabolism; Lectins, C-Type; Male; MCAO; Nerve Tissue Proteins - metabolism; Neurons - drug effects; Neurons - pathology; NF-kappa B - metabolism; Rats; Rats, Sprague-Dawley; Reperfusion Injury - complications; Reperfusion Injury - metabolism; Reperfusion Injury - pathology; Reperfusion Injury - prevention & control; Signal Transduction - drug effects; TLR4/JNK/caspase-3 signaling pathway; Toll-Like Receptor 4 - metabolism; MCAO; TLR4/JNK/caspase-3 signaling pathway; Afibatide; Apoptosis