Changes in Serotype of Streptococcus pneumoniae After the Introduction of the 13-Valent Pneumococcal Vaccine in a Homogenous Population on Jeju Island

• Published in: Infection & chemotherapy Vol. 51; no. 1; pp. 67 - 72
• Main Authors: Yoo, Jeong Rae, Heo, Sang Taek, Oh, Hyunjoo, Oh, Suhyun, Kim, Young Ree, Lee, Keun Hwa
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 01.03.2019; 대한감염학회
• Subjects: Brief Communication; 내과학; Jeju Island; Streptococcus pneumonia; Korea; PCV 13 vaccine; vaccination
• ISSN: 2093-2340; 2092-6448
• DOI: 10.3947/ic.2019.51.1.67

We compared the serotypes of between the pre-pneumococcal conjugate vaccine (PCV)13 era and post-PCV13 era among homogenous inhabitants of an isolated South Korean island. A total of 325 strains were isolated. In the pre-PCV13 era, 19A/F, 15A/F, 19B, and 23A serotypes were identified. In the post-PCV13 era, 15 serotypes were identified. The 19F and 23A serotypes showed the highest prevalence in the pre- and post-PCV13 era, respectively. After PCV13 introduction, the PCV 13 serotype coverage rate was decreased (80.0% and 30.5% in the pre- and post-PCV13 eras, respectively), while the proportion of non-PCV 13 serotypes increased.