A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing - Saulnier, Olivier; Zagozewski, Jamie; Liang, Lisa; Hendrikse, Liam D.; Layug, Paul; Gordon, Victor; Aldinger, Kimberly A.; Haldipur, Parthiv; Borlase, Stephanie; Coudière-Morrison, Ludivine; Cai, Ting; Martell, Emma; et al. (Nature cell biology, 2024)
Keywords: 13; 13/100; 13/95; 38; 38/91; 59; 59/57; 631/136/142; 631/67/1922; 631/67/71; 82; 82/58; Alternative splicing; Alternative Splicing - genetics; Animals; Biomedical and Life Sciences; Cancer Research; Cell Biology; Cell fate; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms - genetics; Cerebellar Neoplasms - metabolism; Cerebellar Neoplasms - pathology; Cerebellum; Developmental Biology; Gene Expression Regulation, Neoplastic; Humans; In vivo methods and tests; Life Sciences; Medulloblastoma; Medulloblastoma - genetics; Medulloblastoma - metabolism; Medulloblastoma - pathology; Mice; Neoplastic Stem Cells - metabolism; Neoplastic Stem Cells - pathology; Otx Transcription Factors - genetics; Otx Transcription Factors - metabolism; Otx2 protein; Protein interaction; Proteins; Stem Cells; Tumors