Oriented Cortical‐Bone‐Like Silk Protein Lamellae Effectively Repair Large Segmental Bone Defects in Pigs - Shuai, Yajun; Yang, Tao; Zheng, Meidan; Zheng, Li; Wang, Jie; Mao, Chuanbin; Yang, Mingying (Advanced materials (Weinheim), 2025)
Keywords: Animals; bio‐manufacturing; Bone Regeneration - drug effects; bone tissue regeneration; Cell Proliferation - drug effects; Cortical Bone; cortical bone organoids; Defects; Endothelial cells; Fibroins - chemistry; freeze‐casting; Growth factors; Human Umbilical Vein Endothelial Cells - cytology; Humans; Lamellar structure; Macrophages; Mesenchymal Stem Cells - cytology; Mesenchymal Stem Cells - metabolism; Osteoblasts - cytology; Proteins; Regeneration (physiology); Scaffolds; Silk; Silk fibroin; Stem cells; Swine; Swine, Miniature; Tissue Scaffolds - chemistry; bone tissue regeneration; bio‐manufacturing; freeze‐casting; cortical bone organoids; silk fibroin