Editorial: Inter- and Intra-subject Variability in Brain Imaging and Decoding

• Published in: Frontiers in computational neuroscience Vol. 15; p. 791129
• Main Authors: Wei, Chun-Shu, Keller, Corey J., Li, Junhua, Lin, Yuan-Pin, Nakanishi, Masaki, Wagner, Johanna, Wu, Wei, Zhang, Yu, Jung, Tzyy-Ping
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 29.11.2021; Frontiers Media S.A
• Subjects: Alzheimer's disease; brain decoding; Brain research; brain-computer interface; Classification; Datasets; Editorials; Education; EEG; Feedback; Genotypes; human variability; Medical imaging; MEG; Neostriatum; Neuroimaging; Neuroscience; Social interactions; Thalamus; United States > US; Taiwan; fMRI; fNIRS; EEG; brain-computer interface; brain decoding; human variability; MEG; neuroimaging
• ISSN: 1662-5188; 1662-5188
• DOI: 10.3389/fncom.2021.791129

[...]questions arise about how to observe, analyze, and model inter- and intra-subject variability, what researchers might gain or lose from this variability, and how to cope with the variability in brain imaging and decoding. According to the findings, patients with different genotypes have different neuroimaging characteristics on causality connections and structural characteristics in the frontal-striatum-thalamus pathway, implying the importance of personalized clinical interventions. The authors measure and show significant test-retest reliability of neuronal activation and physiological responses associated with acute psychosocial stress using Montreal Imaging Stress Tasks. Funding This work was supported by the Ministry of Science and Technology of Taiwan (MOST 109-2222-E-009-006-MY3, 109-2221-E-110-009-MY3), the Higher Education Sprout Project of the National Yang Ming Chiao Tung University and Ministry of Education of Taiwan, the US Army Research Laboratory (W911NF2120154), the US National Science Foundation (CBET-1935860), the US National Institute of Mental Health (R01MH126639 and R01MH129018), Burroughs Wellcome Fund (Career Award for Medical Scientists), a gift to UC San Diego from The Swartz Foundation (Sag Harbor, NY), the National Natural Science Foundation of China (61806149), and the Guangdong Basic and Applied Basic Research Foundation (2020A1515010991).