MMP14 as a central mediator of TGF-β1−induced extracellular matrix remodeling in graves’ orbitopathy - Wang, Xing; Lu, Jing; He, Yuxia; Shu, Qinxin; Lin, Yuxin; Su, Wenqi; Wang, Peng (Frontiers in endocrinology (Lausanne), 2025)
Keywords: Adult; Cells, Cultured; Endocrinology; extracellular matrix; Extracellular Matrix - drug effects; Extracellular Matrix - metabolism; Extracellular Matrix - pathology; Female; Fibroblasts - drug effects; Fibroblasts - metabolism; Fibroblasts - pathology; Fibrosis; Graves Ophthalmopathy - genetics; Graves Ophthalmopathy - metabolism; Graves Ophthalmopathy - pathology; graves’ orbitopathy (GO); Humans; Male; matrix metalloproteinase 14 (MMP14); Matrix Metalloproteinase 14 - genetics; Matrix Metalloproteinase 14 - metabolism; Middle Aged; tissue remodeling; Transforming Growth Factor beta1 - metabolism; Transforming Growth Factor beta1 - pharmacology; fibrosis; tissue remodeling; matrix metalloproteinase 14 (MMP14); extracellular matrix; graves’ orbitopathy (GO)