Adipose Tissue-Derived Stem Cells for Myocardial Regeneration

Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. studies showed the multipotent di...

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Bibliographic Details
Published inKorean circulation journal Vol. 47; no. 2; pp. 151 - 159
Main Authors Joo, Hyung Joon, Kim, Jong-Ho, Hong, Soon Jun
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Society of Cardiology 01.03.2017
대한심장학회
Subjects
Review
내과학
Myocardium
Regeneration
Adipose tissue
Stem cell
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ISSN1738-5520
1738-5555
DOI10.4070/kcj.2016.0207

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Summary:Over the past decade, stem cell therapy has been extensively studied for clinical application for heart diseases. Among various stem cells, adipose tissue-derived stem cell (ADSC) is still an attractive stem cell resource due to its abundance and easy accessibility. studies showed the multipotent differentiation potentials of ADSC, even differentiation into cardiomyocytes. Many pre-clinical animal studies have also demonstrated promising therapeutic results of ADSC. Furthermore, there were several clinical trials showing the positive results in acute myocardial infarction using ADSC. The present article covers the brief introduction, the suggested therapeutic mechanisms, application methods including cell dose and delivery, and human clinical trials of ADSC for myocardial regeneration.
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G704-000708.2017.47.2.005
ISSN:1738-5520
1738-5555
DOI:10.4070/kcj.2016.0207