Clinical features and factors leading to early recurrence of intussusception after saline reduction

• Published in: Journal of the Pakistan Medical Association Vol. 70; no. 10; p. 1
• Main Authors: Shen, Gang, Liu, Huixian, Guan, Zheming, Shang, Xifeng, Li, Junfeng, Zhang, Chuanguang, Zhang, Jing, Liu, Yongdong, Hu, Qiang
• Format: Journal Article
• Language: English
• Published: Pakistan Knowledge Bylanes 01.10.2020
• Subjects: Care and treatment; Case-Control Studies; Child; Child, Preschool; China; Diagnosis; Enema; Humans; Infant; Infant, Newborn; Intussusception; Intussusception - diagnostic imaging; Intussusception - epidemiology; Pediatric diseases; Pediatric research; Recurrence; Recurrence (Disease); Retrospective Studies; Risk factors; Saline Solution - therapeutic use; Treatment Outcome; China; Intussusception, Short-term recurrent, Risk factors
• ISSN: 0030-9982
• DOI: 10.5455/JPMA.21744

To investigate the clinical characteristics of early recurrent intussusception after ultrasound-guided saline reduction, and to explore the factors leading to early recurrence. The retrospective observational case-control study was conducted at Weifang People's Hospital, Shandong, China, and comprised data from January 2015 to December 2017 related to paediatric intussusception patients aged 0-12 years who underwent ultrasound-guided saline enema reduction. The patients were divided into two recurrent and non-recurrent groups. Clinical characteristics of the patients with early recurrence were analysed. Factors compared between the groups were gender, age, onset season, onset-to-treatment time interval, blood in stool, fever, diarrhoea, abdominal pain and vomiting, weight and pathology. Data was analysed using SPSS 22. Of the 672 subjects, 86(13%) were patient with early recurrence while 586(87%) had no early recurrence and acted as controls. Among the patients, 70(81.4%) were aged 6-36 months. In 52(60.5%) patients, recurrence was once, and in 23(26.7%) twice. There were 141 episodes of intussusception; 24(17%) occurring in <12 hours, 85(60.2%) in 12-24 hours. Also, 5(6%) patients required surgery for reduction. Compared to the controls, the second quarter, heavier body weight and pathology were the factors leading to early recurrence of intussusceptions (p<0.05). The second quarter, heavier body weight and pathological leading points were found to be factors leading to early recurrent intussusception.