An Approach to the Synthesis of Spiro[indene-pyridoisoquinoline] Derivatives via 1,4-Dipolar Cycloaddition of Isoquinoline and Acetylene Esters, and (1,3-Dihydro-1,3-dioxo-2H-inden-2-ylidene)malononitrile
A concise and efficient approach to the spiro‐tetrahydroisoquinoline derivatives has been developed by 1,4‐dipolar cycloaddition of zwitterions resulting from isoquinoline and acetylene esters and (1,3‐dihydro‐1,3‐dioxo‐2H‐inden‐2‐ylidene)malononitrile in MeCN at room temperature. The significance o...
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Published in | Helvetica chimica acta Vol. 97; no. 10; pp. 1383 - 1387 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Zürich
WILEY-VCH Verlag
01.10.2014
WILEY‐VCH Verlag Wiley Wiley Subscription Services, Inc |
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ISSN | 0018-019X 1522-2675 |
DOI | 10.1002/hlca.201300459 |
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Abstract | A concise and efficient approach to the spiro‐tetrahydroisoquinoline derivatives has been developed by 1,4‐dipolar cycloaddition of zwitterions resulting from isoquinoline and acetylene esters and (1,3‐dihydro‐1,3‐dioxo‐2H‐inden‐2‐ylidene)malononitrile in MeCN at room temperature. The significance of this method lies in good yields and ease of product purification, and no inert atmosphere is required. The structures of the products were confirmed spectroscopically (IR, 1H‐ and 13C‐NMR, and EI‐MS) and by elemental analyses. A plausible mechanism for this reaction is proposed (Scheme). |
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AbstractList | A concise and efficient approach to the spiro‐tetrahydroisoquinoline derivatives has been developed by 1,4‐dipolar cycloaddition of zwitterions resulting from isoquinoline and acetylene esters and (1,3‐dihydro‐1,3‐dioxo‐2
H
‐inden‐2‐ylidene)malononitrile in MeCN at room temperature. The significance of this method lies in good yields and ease of product purification, and no inert atmosphere is required. The structures of the products were confirmed spectroscopically (IR,
1
H‐ and
13
C‐NMR, and EI‐MS) and by elemental analyses. A plausible mechanism for this reaction is proposed (
Scheme
). A concise and efficient approach to the spiro‐tetrahydroisoquinoline derivatives has been developed by 1,4‐dipolar cycloaddition of zwitterions resulting from isoquinoline and acetylene esters and (1,3‐dihydro‐1,3‐dioxo‐2H‐inden‐2‐ylidene)malononitrile in MeCN at room temperature. The significance of this method lies in good yields and ease of product purification, and no inert atmosphere is required. The structures of the products were confirmed spectroscopically (IR, 1H‐ and 13C‐NMR, and EI‐MS) and by elemental analyses. A plausible mechanism for this reaction is proposed (Scheme). A concise and efficient approach to the spiro-tetrahydroisoquinoline derivatives has been developed by 1,4-dipolar cycloaddition of zwitterions resulting from isoquinoline and acetylene esters and (1,3-dihydro-1,3-dioxo-2H-inden-2-ylidene)malononitrile in MeCN at room temperature. The significance of this method lies in good yields and ease of product purification, and no inert atmosphere is required. The structures of the products were confirmed spectroscopically (IR, H-1- and C-13-NMR, and EI-MS) and by elemental analyses. A plausible mechanism for this reaction is proposed (Scheme). |
Author | Zhu, Long-Guan Alizadeh, Abdolali Sadeghi, Vahideh Bayat, Fahimeh |
Author_xml | – sequence: 1 givenname: Abdolali surname: Alizadeh fullname: Alizadeh, Abdolali email: abdol_alizad@yahoo.com, aalizadeh@modares.ac.ir organization: Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran, (phone: +98-21-88006631; fax: +98-21-88006544) – sequence: 2 givenname: Vahideh surname: Sadeghi fullname: Sadeghi, Vahideh organization: Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran, (phone: +98-21-88006631; fax: +98-21-88006544) – sequence: 3 givenname: Fahimeh surname: Bayat fullname: Bayat, Fahimeh organization: Department of Chemistry, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran, (phone: +98-21-88006631; fax: +98-21-88006544) – sequence: 4 givenname: Long-Guan surname: Zhu fullname: Zhu, Long-Guan organization: Department of Chemistry, Zhejiang University, Hangzhou 310027, P.R. China |
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CitedBy_id | crossref_primary_10_1007_s11030_020_10041_1 crossref_primary_10_1002_chin_201514208 crossref_primary_10_1016_j_molstruc_2024_139741 crossref_primary_10_1002_cjoc_201700142 crossref_primary_10_1002_slct_202102255 crossref_primary_10_1002_slct_201802394 crossref_primary_10_1016_j_tetlet_2016_06_011 crossref_primary_10_1002_ejoc_202100809 crossref_primary_10_1002_hlca_201500194 crossref_primary_10_1002_jhet_3739 crossref_primary_10_1002_slct_201701348 crossref_primary_10_2174_1385272826666220221141306 |
Cites_doi | 10.1055/s-2008-1032033 10.1016/j.tetlet.2008.01.006 10.1016/j.tet.2013.08.071 10.1002/cber.19671000406 10.1002/jlac.19324980103 10.1016/j.tet.2008.01.106 10.1055/s-2008-1067246 10.1021/ol0264004 10.1016/j.tetlet.2005.06.014 10.1016/S0040-4039(02)02649-7 10.1055/s-2007-983814 10.1016/j.tetlet.2008.12.106 |
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Keywords | Propanedinitrile Acetylene esters ACID Cycloadditions DMAD ZWITTERION Spiro-tetrahydroisoquinoline ISOCYANIDES Isoquinoline 3-dioxo-2H-inden-2-ylidene 2- 3-dihydro-1 |
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References | O. Diels , K. Alder , Liebigs Ann. Chem. 1932, 498, 16. A. Alizadeh , N. Zohreh , Synthesis 2008, 429 V. Nair , A. R. Sreekanth , N. Abhilash , M. M. Bhadbhade , R. C. Gonnade , Org. Lett. 2002, 4, 3575. V. Nair , B. R. Devi , L. R. Varma , Tetrahedron Lett. 2005, 46, 5333 A. Alizadeh , Q. Oskueyan , S. Rostamnia , A. Ghanbari-Niaki , A. R. Mohebbi , Synthesis 2008, 2929 A. Shaabani , A. H. Rezayan , A. Sarvary , H. R. Khavasi , Tetrahedron Lett. 2008, 49, 1469. V. Nair , S. Devipriya , E. Suresh , Tetrahedron 2008, 64, 3567. V. Nair , A. R. Sreekanth , A. T. Biju , N. P. Rath , Tetrahedron Lett. 2003, 44, 729 M. A. Terzidis , J. Stephanidou-Stephanatou , C. A. Tsoleridis , Tetrahedron Lett. 2009, 50, 1196 R. Huisgen , M. Morikawa , K. Herbig , E. Brunn , Chem. Ber. 1967, 100, 1094. H.-B. Yang , Y.-Z. Zhao , R. Sang , X.-Y. Tang , M. Shi , Tetrahedron 2013, 69, 9205. A. Alizadeh , Q. Oskueyan , S. Rostamnia , Synthesis 2007, 2637. 2002; 4 2008 2008 2007 2003 2013; 44 69 1967; 100 2005 2008; 46 64 1932; 498 2009 2008; 50 49 e_1_2_1_6_2 e_1_2_1_6_3 e_1_2_1_7_2 e_1_2_1_3_3 e_1_2_1_4_2 e_1_2_1_4_3 e_1_2_1_5_2 e_1_2_1_2_2 e_1_2_1_2_3 e_1_2_1_3_2 e_1_2_1_1_2 e_1_2_1_7_3 e_1_2_1_7_4 Alizadeh, A (WOS:000259610600012) 2008 Diels, O (WOS:000200641100002) 1932; 498 Terzidis, MA (WOS:000263749600011) 2009; 50 Nair, V (WOS:000180464000024) 2003; 44 Alizadeh, A (WOS:000249453100009) 2007 Alizadeh, A (WOS:000253373800017) 2008 Nair, V (WOS:000254596800020) 2008; 64 |
References_xml | – reference: V. Nair , B. R. Devi , L. R. Varma , Tetrahedron Lett. 2005, 46, 5333; – reference: A. Alizadeh , Q. Oskueyan , S. Rostamnia , Synthesis 2007, 2637. – reference: R. Huisgen , M. Morikawa , K. Herbig , E. Brunn , Chem. Ber. 1967, 100, 1094. – reference: A. Shaabani , A. H. Rezayan , A. Sarvary , H. R. Khavasi , Tetrahedron Lett. 2008, 49, 1469. – reference: O. Diels , K. Alder , Liebigs Ann. Chem. 1932, 498, 16. – reference: V. Nair , S. Devipriya , E. Suresh , Tetrahedron 2008, 64, 3567. – reference: A. Alizadeh , N. Zohreh , Synthesis 2008, 429; – reference: V. Nair , A. R. Sreekanth , A. T. Biju , N. P. Rath , Tetrahedron Lett. 2003, 44, 729; – reference: H.-B. Yang , Y.-Z. Zhao , R. Sang , X.-Y. Tang , M. Shi , Tetrahedron 2013, 69, 9205. – reference: V. Nair , A. R. Sreekanth , N. Abhilash , M. M. Bhadbhade , R. C. Gonnade , Org. Lett. 2002, 4, 3575. – reference: A. Alizadeh , Q. Oskueyan , S. Rostamnia , A. Ghanbari-Niaki , A. R. Mohebbi , Synthesis 2008, 2929; – reference: M. A. Terzidis , J. Stephanidou-Stephanatou , C. A. Tsoleridis , Tetrahedron Lett. 2009, 50, 1196; – volume: 100 start-page: 1094 year: 1967 publication-title: Chem. Ber. – volume: 498 start-page: 16 year: 1932 publication-title: Liebigs Ann. Chem. – start-page: 2929 429 2637 year: 2008 2008 2007 publication-title: Synthesis Synthesis Synthesis – volume: 4 start-page: 3575 year: 2002 publication-title: Org. Lett. – volume: 46 64 start-page: 5333 3567 year: 2005 2008 publication-title: Tetrahedron Lett. Tetrahedron – volume: 44 69 start-page: 729 9205 year: 2003 2013 publication-title: Tetrahedron Lett. Tetrahedron – volume: 50 49 start-page: 1196 1469 year: 2009 2008 publication-title: Tetrahedron Lett. Tetrahedron Lett. – ident: e_1_2_1_7_3 doi: 10.1055/s-2008-1032033 – ident: e_1_2_1_3_3 doi: 10.1016/j.tetlet.2008.01.006 – ident: e_1_2_1_4_3 doi: 10.1016/j.tet.2013.08.071 – ident: e_1_2_1_2_3 doi: 10.1002/cber.19671000406 – ident: e_1_2_1_1_2 doi: 10.1002/jlac.19324980103 – ident: e_1_2_1_6_3 doi: 10.1016/j.tet.2008.01.106 – ident: e_1_2_1_7_2 doi: 10.1055/s-2008-1067246 – ident: e_1_2_1_5_2 doi: 10.1021/ol0264004 – ident: e_1_2_1_6_2 doi: 10.1016/j.tetlet.2005.06.014 – ident: e_1_2_1_2_2 – ident: e_1_2_1_4_2 doi: 10.1016/S0040-4039(02)02649-7 – ident: e_1_2_1_7_4 doi: 10.1055/s-2007-983814 – ident: e_1_2_1_3_2 doi: 10.1016/j.tetlet.2008.12.106 – volume: 44 start-page: 729 year: 2003 ident: WOS:000180464000024 article-title: The reaction of isoquinoline and dimethyl acetylenedicarboxylate with 1,2-and 1,4-benzoquinones: a novel synthesis of spiro[1,3]oxazino[2,3-a]isoquinolines publication-title: TETRAHEDRON LETTERS – start-page: 429 year: 2008 ident: WOS:000253373800017 article-title: One-pot synthesis of pyrrolo[2,1-a]isoquinoline-1-carboxamide derivatives via a four-component reaction publication-title: SYNTHESIS-STUTTGART doi: 10.1055/s-2008-1032033 – volume: 50 start-page: 1196 year: 2009 ident: WOS:000263749600011 article-title: Engaging a thiazole-DMAD zwitterion in novel one-pot multicomponent reactions involving chromones. Expeditious synthesis of thiazolo- and chromenothiazolopyridines publication-title: TETRAHEDRON LETTERS doi: 10.1016/j.tetlet.2008.12.106 – start-page: 2929 year: 2008 ident: WOS:000259610600012 article-title: Synthesis of bis(aminofuryl)bicinchoninic amides by a one-pot three-component reaction of isocyanides, acetylenic esters, and bicinchoninic acid publication-title: SYNTHESIS-STUTTGART doi: 10.1055/s-2008-1067246 – start-page: 2637 year: 2007 ident: WOS:000249453100009 article-title: Synthesis of nicotinamide and isonicotinamide derivatives via multicomponent reaction of alkyl isocyanides and acetylenic compounds in the presence of nicotinic or isonicotinic acid publication-title: SYNTHESIS-STUTTGART doi: 10.1055/s-2007-983814 – volume: 498 start-page: 16 year: 1932 ident: WOS:000200641100002 article-title: Syntheses in the hydroaromatic range publication-title: JUSTUS LIEBIGS ANNALEN DER CHEMIE – volume: 64 start-page: 3567 year: 2008 ident: WOS:000254596800020 article-title: Construction of heterocycles via 1,4-dipolar cycloaddition of quinoline-DMAD zwitterion with various dipolarophiles publication-title: TETRAHEDRON doi: 10.1016/j.tet.2008.01.106 |
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Snippet | A concise and efficient approach to the spiro‐tetrahydroisoquinoline derivatives has been developed by 1,4‐dipolar cycloaddition of zwitterions resulting from... A concise and efficient approach to the spiro-tetrahydroisoquinoline derivatives has been developed by 1,4-dipolar cycloaddition of zwitterions resulting from... |
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SubjectTerms | 3-dihydro-1 3-dioxo-2H-inden-2-ylidene Acetylene esters Chemistry Chemistry, Multidisciplinary Cycloadditions Esters Isoquinoline Physical Sciences Propanedinitrile Propanedinitrile, 2‐(1,3‐dihydro‐1,3‐dioxo‐2H‐inden‐2‐ylidene) Science & Technology Spiro-tetrahydroisoquinoline |
Title | An Approach to the Synthesis of Spiro[indene-pyridoisoquinoline] Derivatives via 1,4-Dipolar Cycloaddition of Isoquinoline and Acetylene Esters, and (1,3-Dihydro-1,3-dioxo-2H-inden-2-ylidene)malononitrile |
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