Peptide immunotherapy in allergic asthma generates IL-10–dependent immunological tolerance associated with linked epitope suppression - Campbell, John D.; Buckland, Karen F.; McMillan, Sarah J.; Kearley, Jennifer; Oldfield, William L.G.; Stern, Lawrence J.; Grönlund, Hans; van Hage, Marianne; Reynolds, Catherine J.; Boyton, Rosemary J.; Cobbold, Stephen P.; Kay, A. Barry; et al. (The Journal of experimental medicine, 2009)
Keywords: Allergens - immunology; Animals; Asthma - immunology; Asthma - therapy; Bronchial Hyperreactivity - immunology; Cats; Desensitization, Immunologic; Disease Models, Animal; Double-Blind Method; Epitopes - immunology; Forkhead Transcription Factors - immunology; Genes, MHC Class II; Glycoproteins - genetics; Glycoproteins - immunology; HLA-DR1 Antigen - immunology; Humans; Immune Tolerance - immunology; Interleukin-10 - immunology; Lung - cytology; Lung - immunology; Lung - pathology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Peptides - immunology; Peptides - therapeutic use; Placebos; Randomized Controlled Trials as Topic; Receptors, Interleukin-10 - immunology; Th2 Cells - immunology; Transforming Growth Factor beta - immunology