21-Hydroxylase–deficient nonclassic adrenal hyperplasia is a progressive disorder: A multicenter study - Moran, Carlos; Azziz, Ricardo; Carmina, Enrico; Dewailly, Didier; Fruzzetti, Franca; Ibañez, Lourdes; Knochenhauer, Eric S.; Marcondes, Jose A.M.; Mendonca, Berenice B.; Pignatelli, Duarte; Pugeat, Michel; Rohmer, Vincent; et al. (American journal of obstetrics and gynecology, 2000)
Keywords: 17-alpha-Hydroxyprogesterone - blood; 21-hydroxylase; Acne; Adolescent; adrenal hyperplasia; Adrenal Hyperplasia, Congenital - enzymology; Adrenals. Adrenal axis. Renin-angiotensin system (diseases); Adrenocorticotropic Hormone; Adult; Aging - physiology; Biological and medical sciences; Child; Child, Preschool; Clitoris; clitoromegaly; Cohort Studies; Disease Progression; Endocrinopathies; Female; hirsutism; Hirsutism - etiology; Humans; Medical sciences; Middle Aged; Non tumoral diseases. Target tissue resistance. Benign neoplasms; Oligomenorrhea - etiology; Prospective Studies; Puberty, Precocious - etiology; Retrospective Studies; Vulvar Diseases - blood; Vulvar Diseases - etiology; clitoromegaly; adrenal hyperplasia; hirsutism; Acne; 21-hydroxylase; Endocrinopathy; Human; Adrenal cortex diseases; Enzyme; Deficiency; Multicenter study; Metabolic diseases; Hyperadrenocorticism; Enzymopathy; Genetic disease; Congenital adrenal hyperplasia syndrome; Symptomatology; Cohort study; Adrenal gland diseases; Female; Oxidoreductases; Age; Steroid 21-monooxygenase