Selective inducible nitric oxide inhibition can restore hemodynamics, but does not improve neurological dysfunction in experimentally induced septic shock in rats - Kadoi, Yuji; Goto, Fumio (Anesth Analg, 2004)
Keywords: Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Animals; Biological and medical sciences; Blood Pressure; Blood Pressure - drug effects; Blotting, Western; Calcium; Calcium - physiology; Cecum; Cecum - injuries; Cecum - physiology; Cerebral Cortex; Cerebral Cortex - metabolism; Enzyme Inhibitors; Enzyme Inhibitors - therapeutic use; Heart Rate; Heart Rate - drug effects; Hemodynamics; Hemodynamics - drug effects; Interleukin-1; Interleukin-1 - metabolism; Lysine; Lysine - analogs & derivatives; Lysine - therapeutic use; Male; Medical sciences; Nervous System Diseases; Nervous System Diseases - drug therapy; Nervous System Diseases - etiology; Nitric Oxide; Nitric Oxide - metabolism; Nitric Oxide Synthase; Nitric Oxide Synthase - antagonists & inhibitors; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Shock, Septic; Shock, Septic - complications; Shock, Septic - physiopathology; Tumor Necrosis Factor-alpha; Tumor Necrosis Factor-alpha - metabolism; Tyrosine; Tyrosine - analogs & derivatives; Tyrosine - metabolism; Infection; Vertebrata; Mammalia; Rat; Animal; Nitric oxide; Rodentia; Anesthesia; Hemodynamics