Dietary Inflammatory Index and Cardiometabolic Risk Parameters in Overweight and Sedentary Subjects

• Published in: International journal of environmental research and public health Vol. 14; no. 10; p. 1104
• Main Authors: Camargo-Ramos, Claudia, Correa-Bautista, Jorge, Correa-Rodríguez, María, Ramírez-Vélez, Robinson
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 06.10.2017; MDPI
• Subjects: Adult; Alcohol; Blood Pressure; Body Composition; Body Mass Index; Cardiovascular disease; Cardiovascular Diseases - prevention & control; Cohort Studies; Colombia - epidemiology; Diabetes; Diet; Diet Records; Family medical history; Fatty acids; Female; Glycated Hemoglobin - analysis; Humans; Inflammation; Inflammation - blood; Inflammation - epidemiology; Inflammation - physiopathology; Lipids - blood; Male; Metabolic syndrome; Middle Aged; Nutrition research; Overweight - blood; Overweight - epidemiology; Overweight - physiopathology; Pulse Wave Analysis; Risk Factors; Sedentary Behavior; Studies; Tumor necrosis factor-TNF; Vitamins; United States > US; diet; dietary inflammatory index; cardio-metabolic; overweight
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph14101104

Nutrition has been established as a relevant factor in the development of cardiovascular disease (CVD). We aimed to investigate the relationship between the dietary inflammatory index (DII) and cardiometabolic risk parameters in a cohort of 90 overweight and sedentary adults from Bogotá, Colombia. A 24-h dietary record was used to calculate the DII. Body composition variables, flow-mediated dilation (FMD), pulse wave velocity (PWV), lipid profile, glucose, glycosylated hemoglobin (Hb1Ac), and blood pressure were measured and a cardiometabolic risk score (MetScore) was calculated. A lower DII score (anti-inflammatory diet) was significantly associated with higher high-density lipoprotein-cholesterol (HDL-C) and FMD, and lower Hb1Ac and MetScore (p < 0.05). A lower DII score was inversely correlated with plasma triglyceride levels (r = −0.354, p < 0.05), glucose (r = −0.422, p < 0.05), MetScore (r = −0.228, p < 0.05), and PWV (r = −0.437, p < 0.05), and positively with FMD (r = 0.261, p < 0.05). In contrast, a higher DII score (pro-inflammatory diet) showed a positive relationship with MetScore (r = 0.410, p < 0.05) and a negative relationship with FMD (r = −0.233, p < 0.05). An increased inflammatory potential of diet was inversely associated with an improved cardiometabolic profile, suggesting the importance of promoting anti-inflammatory diets as an effective strategy for preventing CVD.