Transforming growth factor-β modulates pancreatic cancer associated fibroblasts cell shape, stiffness and invasion - Stylianou, Andreas; Gkretsi, Vasiliki; Stylianopoulos, Triantafyllos (Biochimica et biophysica acta, 2018)
Keywords: Atomic force microscopy; Cancer-Associated Fibroblasts - drug effects; Cancer-Associated Fibroblasts - ultrastructure; Cell invasion; Cell mechanics; Cell Shape; Collagen gels; Desmoplasia; Elastic Modulus; Fibroblasts - drug effects; Fibroblasts - ultrastructure; Gene Expression Regulation, Neoplastic - drug effects; Humans; Lamellipodia; Neoplasm Invasiveness; Neoplasm Proteins - biosynthesis; Neoplasm Proteins - genetics; Pancreatic Neoplasms - pathology; Pseudopodia - drug effects; Pseudopodia - ultrastructure; Stress fibers; Stress Fibers - drug effects; Stress Fibers - ultrastructure; Transforming Growth Factor beta - pharmacology; Tumor Cells, Cultured; Tumor Microenvironment; PBS; Atomic force microscopy; ROCK; DMSO; Collagen gels; AFM; Stress fibers; DAPI; PFA; EMT; ECM; Cell mechanics; α-SMA; Desmoplasia; CAFs; Cell invasion; Lamellipodia; FBs; TGF-β; PCR