Toward Angiogenesis Inhibitors Based on the Conjugation of Organometallic Platinum(II) Complexes to RGD Peptides - Zamora, Ana; Gandioso, Albert; Massaguer, Anna; Buenestado, Silvia; Calvis, Carme; Hernández, Jose Luis; Mitjans, Francesc; Rodríguez, Venancio; Ruiz, José; Marchán, Vicente (ChemMedChem, 2018)
Keywords: Angiogenesis; Angiogenesis inhibitors; Angiogenesis Inhibitors - chemical synthesis; Angiogenesis Inhibitors - chemistry; Angiogenesis Inhibitors - pharmacology; Angiogènesi; Antiangiogenics; Anticancer properties; Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Antitumor activity; Cancer; Cell Line, Tumor; Cell Proliferation - drug effects; Chemistry, Medicinal; Compostos organometàl·lics; Conjugates; Conjugation; Cytotoxicity; Càncer; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Endothelial cells; Human Umbilical Vein Endothelial Cells - drug effects; Humans; Inhibitors; Life Sciences & Biomedicine; Molecular Structure; Neovascularization; Neovascularization, Pathologic - drug therapy; Neovascularization, Pathologic - pathology; Oligopeptides - chemical synthesis; Oligopeptides - chemistry; Oligopeptides - pharmacology; Organometallic compounds; Organoplatinum Compounds - chemical synthesis; Organoplatinum Compounds - chemistry; Organoplatinum Compounds - pharmacology; Peptides; Pharmacology & Pharmacy; Platinum; Pèptids; Receptors; Science & Technology; Structure-Activity Relationship; Tumor cell lines; Umbilical vein; inhibitors; APOPTOSIS; angiogenesis; peptides; ANTITUMOR; CILENGITIDE; STRATEGIES; platinum; ANTIANGIOGENIC ACTIVITY; RUTHENIUM(II); cancer; AGENTS; IRIDIUM COMPLEX; INTEGRIN ALPHA(V)BETA ANTAGONISTS