An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial
Objective To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals. Methods In this double blind, cross-over trial, 30 obese subjects were randomized to...
Saved in:
| Published in | Chinese journal of integrative medicine Vol. 21; no. 5; pp. 332 - 338 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Beijing
Chinese Association of Traditional and Western Medicine
01.05.2015
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-0415 1993-0402 |
| DOI | 10.1007/s11655-015-2160-z |
Cover
| Abstract | Objective
To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals.
Methods
In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin (1 g/day) or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales, respectively.
Results
Mean BAI score was found to be significantly reduced following curcumin therapy (
P
=0.03). However, curcumin supplementation did not exert any significant impact on BDI scores (
P
=0.7).
Conclusion
Curcumin has a potential anti-anxiety effect in individuals with obesity. |
|---|---|
| AbstractList | Objective
To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals.
Methods
In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin (1 g/day) or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales, respectively.
Results
Mean BAI score was found to be significantly reduced following curcumin therapy (
P
=0.03). However, curcumin supplementation did not exert any significant impact on BDI scores (
P
=0.7).
Conclusion
Curcumin has a potential anti-anxiety effect in individuals with obesity. OBJECTIVETo investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals.METHODSIn this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin (1 g/day) or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales, respectively.RESULTSMean BAI score was found to be significantly reduced following curcumin therapy (P=0.03). However, curcumin supplementation did not exert any significant impact on BDI scores (P=0.7).CONCLUSIONCurcumin has a potential anti-anxiety effect in individuals with obesity. To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals. In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin (1 g/day) or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales, respectively. Mean BAI score was found to be significantly reduced following curcumin therapy (P=0.03). However, curcumin supplementation did not exert any significant impact on BDI scores (P=0.7). Curcumin has a potential anti-anxiety effect in individuals with obesity. |
| Author | Iranshahi, Mehrdad Mohammadi, Akram Esmaily, Habibollah Ferns, Gordon Ghayour-Mobarhan, Majid Sahebkar, Amirhossein Ganjali, Shiva |
| Author_xml | – sequence: 1 givenname: Habibollah surname: Esmaily fullname: Esmaily, Habibollah organization: Department of Biostatistics and Epidemiology, Research Health Center, School of Health, Mashhad University of Medical Sciences – sequence: 2 givenname: Amirhossein surname: Sahebkar fullname: Sahebkar, Amirhossein organization: Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Biotechnology Research Center, Mashhad University of Medical Sciences – sequence: 3 givenname: Mehrdad surname: Iranshahi fullname: Iranshahi, Mehrdad organization: Biotechnology Research Center, Mashhad University of Medical Sciences – sequence: 4 givenname: Shiva surname: Ganjali fullname: Ganjali, Shiva organization: Department of Modern Sciences and Technologies, Mashhad University of Medical Sciences – sequence: 5 givenname: Akram surname: Mohammadi fullname: Mohammadi, Akram organization: Cardiovascular Research Center, Mashhad University of Medical Sciences – sequence: 6 givenname: Gordon surname: Ferns fullname: Ferns, Gordon organization: Division of Medical Education, University of Brighton – sequence: 7 givenname: Majid surname: Ghayour-Mobarhan fullname: Ghayour-Mobarhan, Majid email: ghayourm@mums.ac.ir organization: Biochemistry of Nutrition Research Center, Mashhad University of Medical Sciences |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25776839$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kU9P3DAQxS0E4l_7AXpBPnJJO3biOMtthaCthNQLPVuJPaZGib3YDmL30-N04cKBk581vzfSvHdGDn3wSMg3Bt8ZgPyRGGuFqICJirMWqt0BOWWrVV1BA_yw6Fbyopk4IWcpPQII2YI4JidcSNl29eqUbNeeOv-MKbuHPrvgabA0_0OK1qLOafnqOep5cmXkae9fHOZteQ01uImY0mJahgMmLMK4Z2fmfkxXdE1j4cLkdmioDj7HMI5F5uj68Qs5soXCr2_vOfl7e3N__au6-_Pz9_X6rtINa3I1dGbFuQDGmTS2G7q2rWsAY5hlzVAD2k4awNrycjmzLUoreDeYRoMVDTb1Obnc793E8DSXQ9XkksZx7D2GOakSUicbKRkU9OINnYcJjdpEN_Vxq97jKoDcAzqGlCJapV3-H1uOvRsVA7UUo_bFqFKMWopRu-JkH5zvyz_z8L0nFdY_YFSPYY6-hPWJ6RW9SaGM |
| CitedBy_id | crossref_primary_10_1002_biof_1522 crossref_primary_10_1016_j_jamda_2016_12_071 crossref_primary_10_1016_j_biopha_2016_11_098 crossref_primary_10_1016_j_heliyon_2023_e21249 crossref_primary_10_1016_j_prenap_2024_100050 crossref_primary_10_1002_jcp_28103 crossref_primary_10_1016_j_ajog_2023_04_028 crossref_primary_10_1038_srep28956 crossref_primary_10_18596_jotcsa_913136 crossref_primary_10_1080_14656566_2016_1198776 crossref_primary_10_1002_jcb_27371 crossref_primary_10_1016_j_phrs_2017_02_008 crossref_primary_10_3390_nu16152414 crossref_primary_10_1002_jcp_25749 crossref_primary_10_1002_ptr_8265 crossref_primary_10_3390_ijms23041964 crossref_primary_10_1002_ptr_7974 crossref_primary_10_3389_fnut_2022_1040259 crossref_primary_10_1016_j_eujim_2021_101400 crossref_primary_10_1016_j_phrs_2017_12_020 crossref_primary_10_7570_jomes19055 crossref_primary_10_1016_j_biopha_2023_116034 crossref_primary_10_3390_antiox13040486 crossref_primary_10_1002_ijc_30224 crossref_primary_10_1007_s12640_017_9860_4 crossref_primary_10_1002_jcp_28072 crossref_primary_10_1016_j_ijbiomac_2021_02_194 crossref_primary_10_1021_acsmedchemlett_7b00284 crossref_primary_10_3390_cimb45020068 crossref_primary_10_1080_10408398_2018_1552244 crossref_primary_10_1007_s40263_017_0423_2 crossref_primary_10_3390_jcm9030746 crossref_primary_10_1055_a_1517_6882 crossref_primary_10_1016_j_ctim_2015_06_010 crossref_primary_10_1002_jcp_25756 crossref_primary_10_1002_biof_1344 crossref_primary_10_1016_j_dsx_2019_07_045 crossref_primary_10_1080_10408398_2021_2021137 crossref_primary_10_3389_fnut_2022_865497 crossref_primary_10_1002_jcb_27192 crossref_primary_10_1080_10408398_2017_1358139 crossref_primary_10_3390_nu13020680 crossref_primary_10_1016_j_phrs_2016_03_026 crossref_primary_10_1007_s11655_023_3732_3 crossref_primary_10_4236_ajps_2021_123030 crossref_primary_10_1002_jcb_27757 crossref_primary_10_3390_foods6100092 crossref_primary_10_1002_ptr_5899 crossref_primary_10_1016_j_heliyon_2023_e16957 crossref_primary_10_1177_0269881116686883 crossref_primary_10_3389_fpsyt_2021_598119 crossref_primary_10_1002_ptr_5659 crossref_primary_10_1002_ptr_5779 crossref_primary_10_3390_life14040479 crossref_primary_10_1021_acsptsci_2c00012 crossref_primary_10_1039_D1FO03752H crossref_primary_10_1080_10408398_2017_1366892 crossref_primary_10_2174_1570159X21666230809112028 crossref_primary_10_1016_j_lfs_2021_120296 crossref_primary_10_1016_j_nut_2018_11_017 crossref_primary_10_3389_fpsyt_2021_765485 crossref_primary_10_1080_10408398_2019_1653260 crossref_primary_10_3390_nu12103158 crossref_primary_10_1016_j_brainresbull_2018_12_015 crossref_primary_10_1080_27697061_2023_2244031 crossref_primary_10_1002_ptr_6054 crossref_primary_10_1002_ptr_6571 crossref_primary_10_1002_ptr_7264 crossref_primary_10_1002_ptr_5524 crossref_primary_10_3390_ijms24054476 crossref_primary_10_1002_biof_1603 crossref_primary_10_3390_ijerph15102093 crossref_primary_10_1002_ptr_5905 crossref_primary_10_1080_07391102_2023_2254409 crossref_primary_10_1155_2019_7359235 crossref_primary_10_1016_j_phrs_2017_07_022 crossref_primary_10_7762_cnr_2019_8_3_196 crossref_primary_10_1080_15384047_2022_2162807 crossref_primary_10_1002_jcb_26121 crossref_primary_10_1080_19390211_2021_1936335 crossref_primary_10_1002_ptr_6323 crossref_primary_10_1016_j_ejphar_2022_175230 crossref_primary_10_3390_foods10092121 crossref_primary_10_1097_WNF_0000000000000553 crossref_primary_10_1016_j_phrs_2018_03_009 crossref_primary_10_3389_fphar_2024_1496661 crossref_primary_10_1016_j_canlet_2017_03_020 crossref_primary_10_1016_j_nut_2016_03_018 crossref_primary_10_1155_2022_6339715 crossref_primary_10_1016_j_ejmech_2018_12_016 crossref_primary_10_32708_uutfd_1202758 crossref_primary_10_1097_FJC_0000000000000406 crossref_primary_10_1007_s12035_018_1169_7 crossref_primary_10_3390_ijms21113956 crossref_primary_10_1089_cmb_2019_0052 crossref_primary_10_1002_ptr_6037 crossref_primary_10_3390_molecules27134014 crossref_primary_10_1016_j_bbi_2019_11_002 crossref_primary_10_1002_jcp_25795 crossref_primary_10_1007_s40263_022_00901_9 crossref_primary_10_1002_jcp_26249 crossref_primary_10_1177_0004867421998795 crossref_primary_10_3389_fnut_2022_966152 crossref_primary_10_1002_jcp_27615 crossref_primary_10_1080_1028415X_2024_2408972 crossref_primary_10_1177_1934578X20901898 crossref_primary_10_1016_j_jnutbio_2018_12_005 crossref_primary_10_1016_j_phrs_2016_12_037 crossref_primary_10_1111_bcpt_13455 crossref_primary_10_1002_brb3_70320 crossref_primary_10_1007_s00737_021_01123_6 crossref_primary_10_1007_s40291_016_0202_7 crossref_primary_10_3390_nu16111728 crossref_primary_10_1007_s00580_016_2339_5 crossref_primary_10_1016_j_lfs_2021_119575 crossref_primary_10_1093_advances_nmz117 crossref_primary_10_1111_bph_13621 crossref_primary_10_1002_ptr_6542 crossref_primary_10_1002_jcp_26212 crossref_primary_10_1007_s10787_016_0301_4 crossref_primary_10_1016_j_clnesp_2024_05_017 crossref_primary_10_1002_biof_1932 crossref_primary_10_1016_j_jff_2019_103599 crossref_primary_10_1016_j_jad_2016_09_047 crossref_primary_10_1016_j_cytogfr_2016_10_001 crossref_primary_10_1002_biof_1376 crossref_primary_10_1016_j_msec_2018_06_030 crossref_primary_10_1016_j_addr_2022_114317 crossref_primary_10_1007_s11356_018_3399_7 crossref_primary_10_1080_17425255_2019_1650914 crossref_primary_10_1002_jcsm_12140 crossref_primary_10_1016_j_jad_2020_12_158 crossref_primary_10_1016_j_prmcm_2023_100222 crossref_primary_10_1080_07315724_2017_1392263 crossref_primary_10_1016_j_ejphar_2016_05_026 |
| Cites_doi | 10.1016/j.brainres.2010.07.007 10.1038/jcbfm.1995.114 10.1001/archpsyc.1961.01710120031004 10.1017/S0007114511006544 10.1002/anie.201107724 10.1007/BF02857359 10.1093/geronj/11.3.298 10.1016/j.brainres.2006.09.009 10.1016/j.ctim.2014.07.006 10.1016/j.psyneuen.2012.05.017 10.1097/00075198-200004000-00005 10.1016/j.bcp.2007.08.016 10.1016/j.plipres.2014.07.002 10.1007/BF02836505 10.1002/jnr.21346 10.1038/sj.mp.4001949 10.1089/ars.2007.1769 10.1016/j.biopsych.2009.03.012 10.1016/j.jff.2013.12.008 10.1258/acb.2012.012040 10.1016/S0378-8741(02)00211-8 10.1037/0022-006X.56.6.893 10.1016/j.brainres.2007.05.071 10.1002/ptr.5149 10.1100/tsw.2009.137 10.1002/biof.1062 10.3922/j.psns.2010.2.013 10.1152/japplphysiol.90470.2008 10.1176/ajp.136.9.1184 10.1002/ptr.4715 10.1016/j.fertnstert.2010.07.1071 10.1016/j.biopsych.2007.01.012 10.1016/j.neures.2010.08.007 10.1002/ptr.4952 10.1016/S0893-133X(96)80057-1 10.1016/j.phymed.2008.02.003 10.1038/mp.2008.59 10.1002/ptr.5045 10.1176/ajp.156.6.966a 10.2174/138945006775515446 10.1016/B978-0-12-398314-5.00001-5 |
| ContentType | Journal Article |
| Copyright | Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2015 |
| Copyright_xml | – notice: Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2015 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1007/s11655-015-2160-z |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1993-0402 |
| EndPage | 338 |
| ExternalDocumentID | 25776839 10_1007_s11655_015_2160_z |
| Genre | Randomized Controlled Trial Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- -5E -5G -BR -EM -SE -S~ -Y2 -~C .86 .VR 06C 06D 0R~ 0VY 1N0 29B 29~ 2B. 2J2 2JN 2JY 2KG 2KM 2LR 2VQ 2~H 30V 36B 4.4 406 408 40D 40E 5GY 5VR 5VS 6NX 6PF 92F 92I 93N 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAWTL AAXDM AAYIU AAYQN AAYTO AAYZH ABAKF ABDZT ABECU ABFTV ABHQN ABJNI ABJOX ABKCH ABMNI ABMQK ABNWP ABQBU ABQSL ABSXP ABTEG ABTKH ABTMW ABWNU ABXPI ACAOD ACDTI ACGFS ACHSB ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACSNA ACUDM ACZOJ ADHIR ADINQ ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFLOW AFQWF AFUIB AFWTZ AFZKB AGAYW AGDGC AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BDATZ BGNMA CAG CAJEE CCEZO CHBEP CIEJG COF CS3 CSCUP CW9 DDRTE DNIVK DPUIP DU5 EBLON EBS EIOEI EJD EMB EMOBN ESBYG F5P FA0 FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GRRUI H13 HF~ HG6 HMJXF HRMNR HVGLF HZ~ IJ- IKXTQ ITM IWAJR I~X I~Z J-C JBSCW JZLTJ LLZTM M4Y MA- NDZJH NPVJJ NQJWS NU0 O9- P9S PF0 PT4 Q-- QOR QOS R89 R9I ROL RPX RSV S16 S1Z S26 S27 S28 S37 S3B SAP SCL SCLPG SDH SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW STPWE SV3 SZ9 SZN T13 T16 TCJ TGQ TSG TT1 TUC U1G U2A U5O U9L UG4 UOJIU UTJUX UZXMN VC2 VFIZW W48 WFFXF WK8 YLTOR Z7U ZMTXR ZOVNA ~A9 AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC ADHKG AEZWR AFDZB AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION CGR CUY CVF ECM EIF NPM 7X8 ABRTQ |
| ID | FETCH-LOGICAL-c414t-b8d922501217df8b8663300dd1f14b30ef87d0e3f21991f6e7f528bd4c0f54e43 |
| IEDL.DBID | AGYKE |
| ISSN | 1672-0415 |
| IngestDate | Tue Aug 05 10:31:11 EDT 2025 Thu Apr 03 06:58:57 EDT 2025 Tue Jul 01 01:09:00 EDT 2025 Thu Apr 24 23:07:58 EDT 2025 Fri Feb 21 02:35:54 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | psychological disorders Beck Anxiety Inventory scale Beck Depression Inventory scale curcumin phenolic |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c414t-b8d922501217df8b8663300dd1f14b30ef87d0e3f21991f6e7f528bd4c0f54e43 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
| PMID | 25776839 |
| PQID | 1678747710 |
| PQPubID | 23479 |
| PageCount | 7 |
| ParticipantIDs | proquest_miscellaneous_1678747710 pubmed_primary_25776839 crossref_citationtrail_10_1007_s11655_015_2160_z crossref_primary_10_1007_s11655_015_2160_z springer_journals_10_1007_s11655_015_2160_z |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2015-05-01 |
| PublicationDateYYYYMMDD | 2015-05-01 |
| PublicationDate_xml | – month: 05 year: 2015 text: 2015-05-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Beijing |
| PublicationPlace_xml | – name: Beijing – name: China |
| PublicationTitle | Chinese journal of integrative medicine |
| PublicationTitleAbbrev | Chin. J. Integr. Med |
| PublicationTitleAlternate | Chin J Integr Med |
| PublicationYear | 2015 |
| Publisher | Chinese Association of Traditional and Western Medicine |
| Publisher_xml | – name: Chinese Association of Traditional and Western Medicine |
| References | Artigas, Adell, Celada (CR41) 2006; 7 Strimpakos, Sharma (CR9) 2008; 10 Su (CR5) 2012; 2 Cassano, Pini, Saettoni, Dell’Osso (CR1) 1999; 156 Kuppusamy, Ohnishi, Numagami, Ohnishi, Zweier (CR8) 1995; 15 Kulkarni, Dhir, Akula (CR23) 2009; 9 Ruhé, Mason, Schene (CR37) 2007; 12 Sahebkar (CR25) 2014; 28 Kumar, Singh (CR27) 2008; 15 Fan, Qian, Wo, Yan, Gao (CR11) 2005; 11 Sahebkar, Chew, Watts (CR16) 2014; 56 Azmitia, Gannon, Kheck, Whitaker-Azmitia (CR40) 1996; 14 Nabiuni, Nazari, Abdolhamid Angaji, Safayi Nejad (CR44) 2011; 5 Morganti-Kossmann, Otto, Stahel, Kossmann (CR6) 2000; 6 Schechter, Ring, Beyer, Hughes, Khawaja, Malberg (CR2) 2005; 2 Salim, Chugh, Asghar (CR36) 2012; 88 Kasper (CR38) 2009; 66 Sahebkar (CR12) 2013; 39 Csiszar, Wang, Lakatta, Ungvari (CR35) 2008; 105 Lovell, Markesbery (CR32) 2007; 85 Panahi, Sahebkar, Parvin, Saadat (CR20) 2012; 49 Xu, Ku, Tie, Yao, Jiang, Ma (CR22) 2006; 1122 Wong, Dong, Maestre-Mesa, Licinio (CR7) 2008; 13 Yu, Kong, Chen (CR43) 2002; 83 van Reedt Dortland, Vreeburg, Giltay, Licht, Vogelzangs, van Veen (CR4) 2013; 38 Gilhotra, Dhingra (CR26) 2010; 1352 CR29 Zheng, Tong, Wu (CR10) 2006; 12 Chimakurthy, Talasila (CR28) 2010; 3 Beck, Ward, Mendelson, Mock, Erbaugh (CR31) 1961; 4 Panahi, Sahebkar, Amiri, Davoudi, Beiraghdar, Hoseininejad (CR21) 2012; 108 Panahi, Saadat, Beiraghdar, Hosseini Nouzari, Jalalian, Sahebkar (CR18) 2014; 6 Sahebkar (CR13) 2010; 94 Skilton, Moulin, Terra, Bonnet (CR3) 2007; 62 Xu, Ku, Cui, Li, Barish, Foster (CR42) 2007; 1162 Sahebkar, Mohammadi, Atabati, Rahiman, Tavallaie, Iranshahi (CR14) 2013; 27 Hovatta, Juhila, Donner (CR34) 2010; 68 Panahi, Saadat, Beiraghdar, Sahebkar (CR17) 2014; 28 Beck, Epstein, Brown, Steer (CR30) 1988; 56 Harman (CR33) 1956; 11 Mohammadi, Sahebkar, Iranshahi, Amini, Khojasteh, Ghayour-Mobarhan (CR45) 2013; 27 Esatbeyoglu, Huebbe, Ernst, Chin, Wagner, Rimbach (CR19) 2012; 51 Goel, Kunnumakkara, Aggarwal (CR24) 2008; 75 Goldberg, Finnerty (CR39) 1979; 136 Panahi, Khalili, Hosseini, Abbasinazari, Sahebkar (CR15) 2014; 22 A Mohammadi (2160_CR45) 2013; 27 MC Morganti-Kossmann (2160_CR6) 2000; 6 MD Kasper (2160_CR38) 2009; 66 A Sahebkar (2160_CR25) 2014; 28 CL Fan (2160_CR11) 2005; 11 A Sahebkar (2160_CR14) 2013; 27 KP Su (2160_CR5) 2012; 2 Y Xu (2160_CR42) 2007; 1162 LD Zheng (2160_CR10) 2006; 12 A Sahebkar (2160_CR12) 2013; 39 Y Panahi (2160_CR20) 2012; 49 F Artigas (2160_CR41) 2006; 7 ZF Yu (2160_CR43) 2002; 83 A Csiszar (2160_CR35) 2008; 105 D Harman (2160_CR33) 1956; 11 Y Panahi (2160_CR18) 2014; 6 LE Schechter (2160_CR2) 2005; 2 MR Skilton (2160_CR3) 2007; 62 MA Lovell (2160_CR32) 2007; 85 HL Goldberg (2160_CR39) 1979; 136 GB Cassano (2160_CR1) 1999; 156 P Kuppusamy (2160_CR8) 1995; 15 SK Kulkarni (2160_CR23) 2009; 9 T Esatbeyoglu (2160_CR19) 2012; 51 Y Panahi (2160_CR21) 2012; 108 M Nabiuni (2160_CR44) 2011; 5 AK Reedt Dortland van (2160_CR4) 2013; 38 J Chimakurthy (2160_CR28) 2010; 3 A Sahebkar (2160_CR13) 2010; 94 AT Beck (2160_CR31) 1961; 4 Y Panahi (2160_CR15) 2014; 22 ML Wong (2160_CR7) 2008; 13 HG Ruhé (2160_CR37) 2007; 12 EC Azmitia (2160_CR40) 1996; 14 S Salim (2160_CR36) 2012; 88 AS Strimpakos (2160_CR9) 2008; 10 I Hovatta (2160_CR34) 2010; 68 N Gilhotra (2160_CR26) 2010; 1352 A Sahebkar (2160_CR16) 2014; 56 2160_CR29 A Kumar (2160_CR27) 2008; 15 Y Panahi (2160_CR17) 2014; 28 Y Xu (2160_CR22) 2006; 1122 A Goel (2160_CR24) 2008; 75 AT Beck (2160_CR30) 1988; 56 7593349 - J Cereb Blood Flow Metab. 1995 Nov;15(6):899-903 25440375 - Complement Ther Med. 2014 Oct;22(5):851-7 22566109 - Angew Chem Int Ed Engl. 2012 May 29;51(22):5308-32 17389902 - Mol Psychiatry. 2007 Apr;12(4):331-59 16800992 - Chin J Integr Med. 2006 Jun;12(2):126-31 3204199 - J Consult Clin Psychol. 1988 Dec;56(6):893-7 20804792 - Neurosci Res. 2010 Dec;68(4):261-75 19882093 - ScientificWorldJournal. 2009 Nov 01;9:1233-41 16475955 - Curr Drug Targets. 2006 Feb;7(2):139-47 17510979 - J Neurosci Res. 2007 Nov 1;85(14):3036-40 23239418 - Biofactors. 2013 Mar-Apr;39(2):197-208 10080568 - Am J Psychiatry. 1999 Mar;156(3):474-6 18504423 - Mol Psychiatry. 2008 Aug;13(8):800-12 18599677 - J Appl Physiol (1985). 2008 Oct;105(4):1333-41 17022948 - Brain Res. 2006 Nov 29;1122(1):56-64 13688369 - Arch Gen Psychiatry. 1961 Jun;4:561-71 22610853 - Phytother Res. 2013 Mar;27(3):374-9 23038702 - Ann Clin Biochem. 2012 Nov;49(Pt 6):580-8 25083925 - Prog Lipid Res. 2014 Oct;56:47-66 24648302 - Phytother Res. 2014 Oct;28(10):1461-7 20797714 - Fertil Steril. 2010 Oct;94(5):e75-6; author reply e77 22814704 - Adv Protein Chem Struct Biol. 2012;88:1-25 17553465 - Biol Psychiatry. 2007 Dec 1;62(11):1251-7 13332224 - J Gerontol. 1956 Jul;11(3):298-300 382878 - Am J Psychiatry. 1979 Sep;136(9):1184-7 17617388 - Brain Res. 2007 Aug 8;1162:9-18 16181535 - Chin J Integr Med. 2005 Sep;11(3):201-4 18586477 - Phytomedicine. 2008 Aug;15(8):577-86 12413724 - J Ethnopharmacol. 2002 Nov;83(1-2):161-5 22717171 - Psychoneuroendocrinology. 2013 Feb;38(2):209-18 19423077 - Biol Psychiatry. 2009 Oct 1;66(7):627-35 18370854 - Antioxid Redox Signal. 2008 Mar;10(3):511-45 23922235 - Phytother Res. 2014 May;28(5):633-42 17900536 - Biochem Pharmacol. 2008 Feb 15;75(4):787-809 23494802 - Phytother Res. 2013 Dec;27(12):1883-8 20633542 - Brain Res. 2010 Sep 17;1352:167-75 22099425 - Br J Nutr. 2012 Oct;108(7):1272-9 8719028 - Neuropsychopharmacology. 1996 Jan;14(1):35-46 16489368 - NeuroRx. 2005 Oct;2(4):590-611 |
| References_xml | – volume: 1352 start-page: 167 year: 2010 end-page: 175 ident: CR26 article-title: GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice publication-title: Brain Res doi: 10.1016/j.brainres.2010.07.007 – volume: 15 start-page: 899 year: 1995 end-page: 903 ident: CR8 article-title: Three-dimensional imaging of nitric oxide production in the rat brain subjected to ischemia-hypoxia publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.1995.114 – volume: 4 start-page: 561 year: 1961 end-page: 571 ident: CR31 article-title: Aninventory for measuring depression publication-title: Arch Gen Psychiatry doi: 10.1001/archpsyc.1961.01710120031004 – volume: 108 start-page: 1272 year: 2012 end-page: 1279 ident: CR21 article-title: Improvement of sulphur mustardinduced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial publication-title: Br J Nutr doi: 10.1017/S0007114511006544 – volume: 51 start-page: 5308 year: 2012 end-page: 5332 ident: CR19 article-title: Curcumin-from molecule to biological function publication-title: Angew Chem Int Ed Engl doi: 10.1002/anie.201107724 – volume: 12 start-page: 126 year: 2006 end-page: 131 ident: CR10 article-title: Growth inhibition and apoptosis inducing mechanisms of curcumin on human ovarian cancer cell line A2780 publication-title: Chin J Integr Med doi: 10.1007/BF02857359 – volume: 11 start-page: 298 year: 1956 end-page: 300 ident: CR33 article-title: Aging: a theory based on free radical and radiation chemistry publication-title: J Gerontol doi: 10.1093/geronj/11.3.298 – volume: 1122 start-page: 56 year: 2006 end-page: 64 ident: CR22 article-title: Curcumin reverses the effects of chronic stress on behavior, the HPA axis, BDNF expression and phosphorylation of CREB publication-title: Brain Res doi: 10.1016/j.brainres.2006.09.009 – volume: 22 start-page: 851 year: 2014 end-page: 857 ident: CR15 article-title: Lipid-modifying effects of adjunctive therapy with curcuminoids-piperine combination in patients with metabolic syndrome: results of a randomized controlled trial publication-title: Complement Ther Med doi: 10.1016/j.ctim.2014.07.006 – volume: 38 start-page: 209 year: 2013 end-page: 218 ident: CR4 article-title: The impact of stress systems and lifestyle on dyslipidemia and obesity in anxiety and depression publication-title: Psychoneuroendocrinology doi: 10.1016/j.psyneuen.2012.05.017 – volume: 6 start-page: 98 year: 2000 end-page: 109 ident: CR6 article-title: The role of inflammation in neurologic disease publication-title: Curr Opin Crit Care doi: 10.1097/00075198-200004000-00005 – volume: 75 start-page: 787 year: 2008 end-page: 809 ident: CR24 article-title: Curcumin as “curecumin”: from kitchen to clinic publication-title: Biochem Pharmacol doi: 10.1016/j.bcp.2007.08.016 – volume: 56 start-page: 47 year: 2014 end-page: 66 ident: CR16 article-title: Recent advances in pharmacotherapy for hypertriglyceridemia publication-title: Prog Lipid Res doi: 10.1016/j.plipres.2014.07.002 – volume: 11 start-page: 201 year: 2005 end-page: 204 ident: CR11 article-title: Effect of curcumin on the gene expression of low density lipoprotein receptors publication-title: Chin J Integr Med doi: 10.1007/BF02836505 – volume: 85 start-page: 3036 year: 2007 end-page: 3040 ident: CR32 article-title: Oxidative damage in mild cognitive impairment and early Alzheimer’s disease publication-title: J Neurosci Res doi: 10.1002/jnr.21346 – ident: CR29 – volume: 12 start-page: 331 year: 2007 end-page: 359 ident: CR37 article-title: Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001949 – volume: 10 start-page: 511 year: 2008 end-page: 545 ident: CR9 article-title: Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials publication-title: Antioxid Redox Signal doi: 10.1089/ars.2007.1769 – volume: 2 start-page: 68 year: 2012 end-page: 74 ident: CR5 article-title: Inflammation in psychopathology of depression: Clinical, biological, and therapeutic implications publication-title: BioMedicine (Netherlands) – volume: 66 start-page: 627 year: 2009 end-page: 635 ident: CR38 article-title: The serotonin-1A receptor in anxiety disorders publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2009.03.012 – volume: 6 start-page: 615 year: 2014 end-page: 622 ident: CR18 article-title: Antioxidant effects of bioavailability-enhanced curcuminoids in patients with solid tumors: a randomized double-blind placebo-controlled trial publication-title: J Funct Foods doi: 10.1016/j.jff.2013.12.008 – volume: 49 start-page: 580 year: 2012 end-page: 588 ident: CR20 article-title: A randomized controlled trial on the anti-inflammatory effects of curcumin in patients with chronic sulphur mustard-induced cutaneous complications publication-title: Ann Clin Biochem doi: 10.1258/acb.2012.012040 – volume: 83 start-page: 161 year: 2002 end-page: 165 ident: CR43 article-title: Antidepressant activity of aqueous extracts of Curcuma longa in mice publication-title: J Ethnopharmacol doi: 10.1016/S0378-8741(02)00211-8 – volume: 2 start-page: 590 year: 2005 end-page: 611 ident: CR2 article-title: Innovative approaches for the development of antidepressant drugs: current and future strategies publication-title: J Am Soc Exp Neurother – volume: 56 start-page: 893 year: 1988 end-page: 897 ident: CR30 article-title: An inventory for measuring clinical anxiety: psychometric properties publication-title: J Consult Clin Psychol doi: 10.1037/0022-006X.56.6.893 – volume: 1162 start-page: 9 year: 2007 end-page: 18 ident: CR42 article-title: Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brainderived neurotrophic factor expression in chronically stressed rats publication-title: Brain Res doi: 10.1016/j.brainres.2007.05.071 – volume: 28 start-page: 1461 year: 2014 end-page: 1467 ident: CR17 article-title: Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors: a randomized double-blind placebo-controlled trial publication-title: Phytother Res doi: 10.1002/ptr.5149 – volume: 9 start-page: 1233 year: 2009 end-page: 1241 ident: CR23 article-title: Potentials of curcumin as an antidepressant publication-title: Sci World J doi: 10.1100/tsw.2009.137 – volume: 39 start-page: 197 year: 2013 end-page: 208 ident: CR12 article-title: Why it is necessary to translate curcumin into clinical practice for the prevention and treatment of metabolic syndrome publication-title: Biofactors doi: 10.1002/biof.1062 – volume: 3 start-page: 239 year: 2010 end-page: 244 ident: CR28 article-title: Effects of curcumin on pentylenetetrazole-induced anxiety like behaviors and associated changes in cognition and monoamine levels publication-title: Psychol Neurosci doi: 10.3922/j.psns.2010.2.013 – volume: 105 start-page: 1333 year: 2008 end-page: 1341 ident: CR35 article-title: Inflammation and endothelial dysfunction during aging: role of NF-?B publication-title: J Appl Physiol doi: 10.1152/japplphysiol.90470.2008 – volume: 136 start-page: 1184 year: 1979 end-page: 1187 ident: CR39 article-title: The comparative efficacy of buspirone and diazepam in the treatment of anxiety publication-title: Am J Psychiatry doi: 10.1176/ajp.136.9.1184 – volume: 27 start-page: 374 year: 2013 end-page: 379 ident: CR45 article-title: Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial publication-title: Phytother Res doi: 10.1002/ptr.4715 – volume: 94 start-page: 75 year: 2010 ident: CR13 article-title: Molecular mechanisms for curcumin benefits against ischemic injury publication-title: Fertil Steril doi: 10.1016/j.fertnstert.2010.07.1071 – volume: 62 start-page: 1251 year: 2007 end-page: 1257 ident: CR3 article-title: Associations between anxiety, depression, and the metabolic syndrome publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2007.01.012 – volume: 68 start-page: 261 year: 2010 end-page: 275 ident: CR34 article-title: Oxidative stress in anxiety and comorbid disorders publication-title: Neurosci Res doi: 10.1016/j.neures.2010.08.007 – volume: 27 start-page: 1883 year: 2013 end-page: 1888 ident: CR14 article-title: Curcuminoids modulate prooxidant- antioxidant balance but not the immune response to heat shock protein 27 and oxidized LDL in obese individuals publication-title: Phytother Res doi: 10.1002/ptr.4952 – volume: 14 start-page: 35 year: 1996 end-page: 46 ident: CR40 article-title: Cellular localization of the 5-HT1A receptor in primate brain neurons and glial cells publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(96)80057-1 – volume: 15 start-page: 577 year: 2008 end-page: 586 ident: CR27 article-title: Possible nitric oxide modulation in protective effect of (Curcuma longa, Zingiberaceae) against sleep deprivation-induced behavioral alterations and oxidative damage in mice publication-title: Phytomedicine doi: 10.1016/j.phymed.2008.02.003 – volume: 13 start-page: 800 year: 2008 end-page: 812 ident: CR7 article-title: Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response publication-title: Mol Psychiatry doi: 10.1038/mp.2008.59 – volume: 28 start-page: 633 year: 2014 end-page: 642 ident: CR25 article-title: Are curcuminoids effective C-reactive proteinlowering agents in clinical practice? Evidence from a metaanalysis publication-title: Phytother Res doi: 10.1002/ptr.5045 – volume: 156 start-page: 474 year: 1999 end-page: 476 ident: CR1 article-title: Multiple anxiety disorder comorbidity in patients with mood spectrum disorders with psychotic features publication-title: Am J Psychiatry doi: 10.1176/ajp.156.6.966a – volume: 7 start-page: 139 year: 2006 end-page: 147 ident: CR41 article-title: Pindolol augmentation of antidepressant response publication-title: Curr Drug Targets doi: 10.2174/138945006775515446 – volume: 88 start-page: 1 year: 2012 end-page: 25 ident: CR36 article-title: Inflammation in anxiety publication-title: Adv Protein Chem Struct Biol doi: 10.1016/B978-0-12-398314-5.00001-5 – volume: 5 start-page: 2224 year: 2011 end-page: 2240 ident: CR44 article-title: Neuroprotective effects of curcumin publication-title: Aust J Basic Appl Sci – volume: 5 start-page: 2224 year: 2011 ident: 2160_CR44 publication-title: Aust J Basic Appl Sci – volume: 39 start-page: 197 year: 2013 ident: 2160_CR12 publication-title: Biofactors doi: 10.1002/biof.1062 – volume: 85 start-page: 3036 year: 2007 ident: 2160_CR32 publication-title: J Neurosci Res doi: 10.1002/jnr.21346 – volume: 12 start-page: 126 year: 2006 ident: 2160_CR10 publication-title: Chin J Integr Med doi: 10.1007/BF02857359 – volume: 49 start-page: 580 year: 2012 ident: 2160_CR20 publication-title: Ann Clin Biochem doi: 10.1258/acb.2012.012040 – volume: 1122 start-page: 56 year: 2006 ident: 2160_CR22 publication-title: Brain Res doi: 10.1016/j.brainres.2006.09.009 – volume: 62 start-page: 1251 year: 2007 ident: 2160_CR3 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2007.01.012 – ident: 2160_CR29 – volume: 11 start-page: 201 year: 2005 ident: 2160_CR11 publication-title: Chin J Integr Med doi: 10.1007/BF02836505 – volume: 1352 start-page: 167 year: 2010 ident: 2160_CR26 publication-title: Brain Res doi: 10.1016/j.brainres.2010.07.007 – volume: 68 start-page: 261 year: 2010 ident: 2160_CR34 publication-title: Neurosci Res doi: 10.1016/j.neures.2010.08.007 – volume: 22 start-page: 851 year: 2014 ident: 2160_CR15 publication-title: Complement Ther Med doi: 10.1016/j.ctim.2014.07.006 – volume: 12 start-page: 331 year: 2007 ident: 2160_CR37 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001949 – volume: 6 start-page: 98 year: 2000 ident: 2160_CR6 publication-title: Curr Opin Crit Care doi: 10.1097/00075198-200004000-00005 – volume: 7 start-page: 139 year: 2006 ident: 2160_CR41 publication-title: Curr Drug Targets doi: 10.2174/138945006775515446 – volume: 88 start-page: 1 year: 2012 ident: 2160_CR36 publication-title: Adv Protein Chem Struct Biol doi: 10.1016/B978-0-12-398314-5.00001-5 – volume: 38 start-page: 209 year: 2013 ident: 2160_CR4 publication-title: Psychoneuroendocrinology doi: 10.1016/j.psyneuen.2012.05.017 – volume: 2 start-page: 68 year: 2012 ident: 2160_CR5 publication-title: BioMedicine (Netherlands) – volume: 9 start-page: 1233 year: 2009 ident: 2160_CR23 publication-title: Sci World J doi: 10.1100/tsw.2009.137 – volume: 94 start-page: 75 year: 2010 ident: 2160_CR13 publication-title: Fertil Steril doi: 10.1016/j.fertnstert.2010.07.1071 – volume: 1162 start-page: 9 year: 2007 ident: 2160_CR42 publication-title: Brain Res doi: 10.1016/j.brainres.2007.05.071 – volume: 13 start-page: 800 year: 2008 ident: 2160_CR7 publication-title: Mol Psychiatry doi: 10.1038/mp.2008.59 – volume: 27 start-page: 374 year: 2013 ident: 2160_CR45 publication-title: Phytother Res doi: 10.1002/ptr.4715 – volume: 66 start-page: 627 year: 2009 ident: 2160_CR38 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2009.03.012 – volume: 105 start-page: 1333 year: 2008 ident: 2160_CR35 publication-title: J Appl Physiol doi: 10.1152/japplphysiol.90470.2008 – volume: 28 start-page: 633 year: 2014 ident: 2160_CR25 publication-title: Phytother Res doi: 10.1002/ptr.5045 – volume: 51 start-page: 5308 year: 2012 ident: 2160_CR19 publication-title: Angew Chem Int Ed Engl doi: 10.1002/anie.201107724 – volume: 136 start-page: 1184 year: 1979 ident: 2160_CR39 publication-title: Am J Psychiatry doi: 10.1176/ajp.136.9.1184 – volume: 10 start-page: 511 year: 2008 ident: 2160_CR9 publication-title: Antioxid Redox Signal doi: 10.1089/ars.2007.1769 – volume: 108 start-page: 1272 year: 2012 ident: 2160_CR21 publication-title: Br J Nutr doi: 10.1017/S0007114511006544 – volume: 56 start-page: 47 year: 2014 ident: 2160_CR16 publication-title: Prog Lipid Res doi: 10.1016/j.plipres.2014.07.002 – volume: 15 start-page: 577 year: 2008 ident: 2160_CR27 publication-title: Phytomedicine doi: 10.1016/j.phymed.2008.02.003 – volume: 156 start-page: 474 year: 1999 ident: 2160_CR1 publication-title: Am J Psychiatry doi: 10.1176/ajp.156.6.966a – volume: 15 start-page: 899 year: 1995 ident: 2160_CR8 publication-title: J Cereb Blood Flow Metab doi: 10.1038/jcbfm.1995.114 – volume: 27 start-page: 1883 year: 2013 ident: 2160_CR14 publication-title: Phytother Res doi: 10.1002/ptr.4952 – volume: 3 start-page: 239 year: 2010 ident: 2160_CR28 publication-title: Psychol Neurosci doi: 10.3922/j.psns.2010.2.013 – volume: 56 start-page: 893 year: 1988 ident: 2160_CR30 publication-title: J Consult Clin Psychol doi: 10.1037/0022-006X.56.6.893 – volume: 2 start-page: 590 year: 2005 ident: 2160_CR2 publication-title: J Am Soc Exp Neurother – volume: 75 start-page: 787 year: 2008 ident: 2160_CR24 publication-title: Biochem Pharmacol doi: 10.1016/j.bcp.2007.08.016 – volume: 6 start-page: 615 year: 2014 ident: 2160_CR18 publication-title: J Funct Foods doi: 10.1016/j.jff.2013.12.008 – volume: 28 start-page: 1461 year: 2014 ident: 2160_CR17 publication-title: Phytother Res doi: 10.1002/ptr.5149 – volume: 4 start-page: 561 year: 1961 ident: 2160_CR31 publication-title: Arch Gen Psychiatry doi: 10.1001/archpsyc.1961.01710120031004 – volume: 11 start-page: 298 year: 1956 ident: 2160_CR33 publication-title: J Gerontol doi: 10.1093/geronj/11.3.298 – volume: 14 start-page: 35 year: 1996 ident: 2160_CR40 publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(96)80057-1 – volume: 83 start-page: 161 year: 2002 ident: 2160_CR43 publication-title: J Ethnopharmacol doi: 10.1016/S0378-8741(02)00211-8 – reference: 23494802 - Phytother Res. 2013 Dec;27(12):1883-8 – reference: 17553465 - Biol Psychiatry. 2007 Dec 1;62(11):1251-7 – reference: 10080568 - Am J Psychiatry. 1999 Mar;156(3):474-6 – reference: 18370854 - Antioxid Redox Signal. 2008 Mar;10(3):511-45 – reference: 17900536 - Biochem Pharmacol. 2008 Feb 15;75(4):787-809 – reference: 20633542 - Brain Res. 2010 Sep 17;1352:167-75 – reference: 23239418 - Biofactors. 2013 Mar-Apr;39(2):197-208 – reference: 16800992 - Chin J Integr Med. 2006 Jun;12(2):126-31 – reference: 19882093 - ScientificWorldJournal. 2009 Nov 01;9:1233-41 – reference: 13688369 - Arch Gen Psychiatry. 1961 Jun;4:561-71 – reference: 23038702 - Ann Clin Biochem. 2012 Nov;49(Pt 6):580-8 – reference: 25083925 - Prog Lipid Res. 2014 Oct;56:47-66 – reference: 16181535 - Chin J Integr Med. 2005 Sep;11(3):201-4 – reference: 7593349 - J Cereb Blood Flow Metab. 1995 Nov;15(6):899-903 – reference: 3204199 - J Consult Clin Psychol. 1988 Dec;56(6):893-7 – reference: 22610853 - Phytother Res. 2013 Mar;27(3):374-9 – reference: 382878 - Am J Psychiatry. 1979 Sep;136(9):1184-7 – reference: 24648302 - Phytother Res. 2014 Oct;28(10):1461-7 – reference: 18586477 - Phytomedicine. 2008 Aug;15(8):577-86 – reference: 22566109 - Angew Chem Int Ed Engl. 2012 May 29;51(22):5308-32 – reference: 20797714 - Fertil Steril. 2010 Oct;94(5):e75-6; author reply e77 – reference: 12413724 - J Ethnopharmacol. 2002 Nov;83(1-2):161-5 – reference: 17510979 - J Neurosci Res. 2007 Nov 1;85(14):3036-40 – reference: 22814704 - Adv Protein Chem Struct Biol. 2012;88:1-25 – reference: 18504423 - Mol Psychiatry. 2008 Aug;13(8):800-12 – reference: 23922235 - Phytother Res. 2014 May;28(5):633-42 – reference: 19423077 - Biol Psychiatry. 2009 Oct 1;66(7):627-35 – reference: 18599677 - J Appl Physiol (1985). 2008 Oct;105(4):1333-41 – reference: 17022948 - Brain Res. 2006 Nov 29;1122(1):56-64 – reference: 22717171 - Psychoneuroendocrinology. 2013 Feb;38(2):209-18 – reference: 22099425 - Br J Nutr. 2012 Oct;108(7):1272-9 – reference: 17389902 - Mol Psychiatry. 2007 Apr;12(4):331-59 – reference: 25440375 - Complement Ther Med. 2014 Oct;22(5):851-7 – reference: 16475955 - Curr Drug Targets. 2006 Feb;7(2):139-47 – reference: 20804792 - Neurosci Res. 2010 Dec;68(4):261-75 – reference: 13332224 - J Gerontol. 1956 Jul;11(3):298-300 – reference: 8719028 - Neuropsychopharmacology. 1996 Jan;14(1):35-46 – reference: 16489368 - NeuroRx. 2005 Oct;2(4):590-611 – reference: 17617388 - Brain Res. 2007 Aug 8;1162:9-18 |
| SSID | ssj0057605 |
| Score | 2.4269965 |
| Snippet | Objective
To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of... To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms... OBJECTIVETo investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of... |
| SourceID | proquest pubmed crossref springer |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 332 |
| SubjectTerms | Adult Anxiety - complications Anxiety - drug therapy Curcumin - therapeutic use Demography Depression - complications Depression - drug therapy Female Humans Male Medicine Medicine & Public Health Obesity - complications Obesity - drug therapy Original Article Placebos Psychiatric Status Rating Scales |
| Title | An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial |
| URI | https://link.springer.com/article/10.1007/s11655-015-2160-z https://www.ncbi.nlm.nih.gov/pubmed/25776839 https://www.proquest.com/docview/1678747710 |
| Volume | 21 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1JS8QwFH64gHhxX8aNCJ6USLqk7Xgr4oKiJwf0VCYbDGordgo6v96XNp3BFTy1pWnaJK8vX3jf-wJw4CFGRjSkqa8Yo2Hc51QIK1sZBbFRRnebDO-b2-iyF17d83uXx122bPc2JFl76kmymxdxSzTj1PciRkfTMMtxfYJ_42x68XB91jpgRNA1c9GLYp_aDPQ2mPlTJZ-no28Y81t8tJ52zhfhrv3ghm3yeFwNxbEcfdFy_GeLlmDBwVCSNnazDFM6X4G5GxdoX4X3NCeDiQRHkZPCEMSKxPE_7KWsXmX1PMBbOennb5b8iUdFxuRaWwUphC41GYzzvsoTkhKcIFXxPBhpRRxX_glP6x1E1qB3fnZ3ekndLg1Uhl44pCJRXXQKVhsuViYRCWKYgDGlPOOFImDaJLFiOjC-ZVmZSMeG-4lQoWSGhzoM1mEmL3K9CYSj4eh-hO0wCItEIlhiulIyoQ2XgnkdYO1gZdJJmNudNJ6yifiy7dIMuzSzXZqNOnA4fuSl0e_4q_B-awEZ_mU2dNLPdVGVGdpSggsvhGMd2GhMY1wdOj1cswXdDhy1w5w5R1D-_q6tf5Xehnnf2knNtNyBmeFrpXcRDQ3FnrP-PZju-ekHETMCWA |
| linkProvider | Springer Nature |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1bS8MwFD7oBPVFvDuvEXxSAum99W2IY-q2pw32FpYmgcHWyrqB7td70suGTAWf2tI0pf1yTr5wvnMCcGchR0Y2pKgtGaNuMPSoEKZspe8EWmoVFRnena7f6ruvA29Q5nFnldq9CknmnnqV7Gb5nhGaedS2fEYXm7BlooxmxdW3G5X7Rf6c6xYtP7CpyT-vQpk_dfF9MlpjmGvR0XzSae7DXskWSaOA9wA2VHII250yHn4En42EjFaVMtKEpJogpSOlTMNcxvNpPJ-M8FZChsmH0WjiUZKlBtZ0QVKhMkVGy_Ss7JE0CM5jMp2MFkqSUtI-xtN8o49j6Defe08tWm6mQGPXcmdUhDJC2zUl3AKpQxEi1XAYk9LSliscpnQYSKYcbRsxlPZVoD07FNKNmfZc5TonUEvSRJ0B8RBfNfTxOzSyFxEKFuoojplQ2osFs-rAqr_K47LSuNnwYsxXNZINEByB4AYIvqjD_fKR96LMxl-NbyuoOBqDiXAME5XOM46gh7g-QtZUh9MCw2V36JtwaeVEdXioQOWlvWa_v-v8X61vYKfV67R5-6X7dgG7thlpuTjyEmqz6VxdIYGZiet8wH4BxxLnRg |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1dT9RAFL3RJSG-IKLCIuiY-KQZmLbTj-VtA6wIQnyQBJ_Gna9kA0wJbRPdX8-d7XQ3gpoYn9qm02ln5nbmTO655wK8ixAjIxoyNNaMUZ6PUyqll63MktxqawZthPfpWXZ0zo8v0ouQ57Tq2O6dS7KNafAqTa7evdF2dxH4FmWpJ52lNI4yRqePYYn7FBI9WBp-_HZy2E3GiKZnLMYoy2Pqo9E7x-bvKvl1aXqANx_4SmdL0OgpfO8-vmWeXO40tdxR03u6jv_RulVYCfCUDFt7egaPjFuD5dPggH8OP4eOTBbSHKUjpSWIIUnghfhL1dyq5nqCtxwZux-eFIpHTeakW18FKaWpDJnM48GqPTIkuHDq8noyNZoEDv0Vns4yi7yA89Hh1_0jGrI3UMUjXlNZ6AFOFl4zLte2kAVim4QxrSMbcZkwY4tcM5PY2LOvbGZym8aF1Fwxm3LDk5fQc6UzG0BSNCgzzrAdFuGSLCQr7EApJo1NlWRRH1g3cEIFaXOfYeNKLESZfZcK7FLhu1RM-_B-_shNq-vxt8JvO2sQ-Pd5l8rYmbKpBNpVgRsyhGl9WG_NZF4dToa4l0sGffjQDbkIE0T153dt_lPpN7D85WAkPn86O3kFT2JvMjMy5hb06tvGbCNgquXr8FPcAQJzDTs |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=An+investigation+of+the+effects+of+curcumin+on+anxiety+and+depression+in+obese+individuals%3A+A+randomized+controlled+trial&rft.jtitle=Chinese+journal+of+integrative+medicine&rft.au=Esmaily%2C+Habibollah&rft.au=Sahebkar%2C+Amirhossein&rft.au=Iranshahi%2C+Mehrdad&rft.au=Ganjali%2C+Shiva&rft.date=2015-05-01&rft.issn=1672-0415&rft.eissn=1993-0402&rft.volume=21&rft.issue=5&rft.spage=332&rft.epage=338&rft_id=info:doi/10.1007%2Fs11655-015-2160-z&rft.externalDBID=n%2Fa&rft.externalDocID=10_1007_s11655_015_2160_z |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1672-0415&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1672-0415&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1672-0415&client=summon |