Dose proportionality and comparison of single and multiple dose pharmacokinetics of fexofenadine (MDL 16 455) and its enantiomers in healthy male volunteers - Robbins, Doris K.; Castles, Mark A.; Pack, David J.; Bhargava, Vijay O.; Weir, Scott J. (Biopharmaceutics & drug disposition, 1998)
Keywords: achiral; Adult; Area Under Curve; Biological and medical sciences; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; enantiomers; fexofenadine hydrochloride; healthy males; Histamine and antagonists. Allergy; Histamine H1 Antagonists - administration & dosage; Histamine H1 Antagonists - pharmacokinetics; Humans; Male; MDL 16 455; Medical sciences; Middle Aged; pharmacokinetics; Pharmacology. Drug treatments; Spectrometry, Fluorescence; Stereoisomerism; Terfenadine - administration & dosage; Terfenadine - analogs & derivatives; Terfenadine - pharmacokinetics; Human; Single dose; Oral administration; Fexofenadine; Normal; Antihistaminic; Dose activity relation; Multiple dose; Stereoselectivity; Enantiomer; Antagonist; Pharmacokinetics; H1 Histamine receptor