VKORC1 , CYP2C9 and CYP4F2 Genetic-based Algorithm for Warfarin Dosing: An Italian Retrospective Study - Zambon, Carlo-Federico; Pengo, Vittorio; Padrini, Roberto; Basso, Daniela; Schiavon, Stefania; Fogar, Paola; Nisi, Alessandra; Frigo, Anna Chiara; Moz, Stefania; Pelloso, Michela; Plebani, Mario (Pharmacogenomics, 2011)
Keywords: Adult; Aged; Aged, 80 and over; Algorithms; Aryl Hydrocarbon Hydroxylases - genetics; Blood Coagulation - drug effects; Blood Coagulation - genetics; Cytochrome P-450; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System - genetics; Cytochrome P450 Family 4; Dosage and administration; Dose-Response Relationship, Drug; Female; Genetic algorithms; Genetic aspects; Humans; Italy; Male; Middle Aged; Mixed Function Oxygenases - genetics; Pharmacogenetics; Physiological aspects; Polymorphism, Genetic; Precision Medicine; Retrospective Studies; Single nucleotide polymorphisms; Vitamin K Epoxide Reductases; Warfarin; Warfarin - administration & dosage; Warfarin - adverse effects; Warfarin - pharmacokinetics; Warfarin - therapeutic use; Italy