Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators - Klinkhammer, Werner; Müller, Henrik; Globisch, Christoph; Pajeva, Ilza K.; Wiese, Michael (Bioorganic & medicinal chemistry, 2009)
Keywords: Animals; Antineoplastic agents; ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors; ATP-Binding Cassette, Sub-Family B, Member 1 - physiology; Biological and medical sciences; Dogs; Drug Resistance, Multiple - drug effects; General aspects; Magnetic Resonance Spectroscopy; Medical sciences; Models, Molecular; Multidrug resistance modulators; P-Glycoprotein; Pharmacology. Drug treatments; BCRP; ABC; P-gp; Multidrug resistance modulators; MDR; MRP; P-Glycoprotein; Nitro compound; P Glycoprotein; Kidney; Ovary; Structure activity relation; Chemical compound library; Multiple resistance; Ureas; Inhibition; Small molecule; Chemical synthesis; Dog; Tumor cell; Carrier protein; Human; Transmembrane protein; Fissipedia; Carnivora; Drug combination; Isoquinoline derivatives; Hydrophobic compound; Vertebrata; Mammalia; Cell line; Carboxamide; Reversibility; Chemosensitizing agent; ABC transporter