Chemical and biological studies of reveromycin A

The research on antibiotics requires the integration of broad areas, such as microbiology, organic chemistry, biochemistry and pharmacology. It is similar to the field of chemical biology that is recently popular as an approach for drug discovery. When we isolate a new compound from a microorganism,...

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Bibliographic Details
Published in	Journal of antibiotics Vol. 69; no. 10; pp. 723 - 730
Main Author	Osada, Hiroyuki
Format	Journal Article
Language	English
Published	London Nature Publishing Group UK 01.10.2016 Nature Publishing Group
Subjects	631/92/436 Animals Antibiotics Antibiotics, Antineoplastic - chemistry Antibiotics, Antineoplastic - pharmacology Bacteriology Biomedical and Life Sciences Bioorganic Chemistry Cell Line, Tumor Disease Models, Animal Drug Discovery Humans Life Sciences Medicinal Chemistry Mice Microbiology Organic Chemistry Osteoclasts - drug effects Pharmacology Pyrans - chemistry Pyrans - pharmacology review-article Spiro Compounds - chemistry Spiro Compounds - pharmacology Structure-Activity Relationship
Online Access	Get full text
ISSN	0021-8820 1881-1469 1881-1469
DOI	10.1038/ja.2016.57

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Summary:	The research on antibiotics requires the integration of broad areas, such as microbiology, organic chemistry, biochemistry and pharmacology. It is similar to the field of chemical biology that is recently popular as an approach for drug discovery. When we isolate a new compound from a microorganism, we can pursue the interesting research on chemistry and biology. In this review, I would like to introduce our achievements in relation to reveromycin A.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ISSN:	0021-8820 1881-1469 1881-1469
DOI:	10.1038/ja.2016.57