Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions - Mygind, Leda; Bergh, Marianne Skov-Skov; Tejsi, Vivien; Vaitheeswaran, Ramanan; Lambertsen, Kate L.; Finsen, Bente; Metaxas, Athanasios (Cells (Basel, Switzerland), 2021)
Keywords: Age; aging; Animal cognition; Animals; Cognition; Cognition - drug effects; Cognitive ability; Cytokines; Experiments; Female; Gene Expression Regulation; Hippocampus; Hippocampus - metabolism; Immunity; Immunological memory; Inflammation; Laboratories; Lipopolysaccharides; Lipopolysaccharides - pharmacology; LPS; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurogenesis; Neurotransmitter Agents - metabolism; Norepinephrine; Observational learning; Physiology; RNA, Messenger - genetics; RNA, Messenger - metabolism; Rodents; sickness behavior; Spatial discrimination learning; Spatial Learning; Spatial memory; Synaptic plasticity; TNF; Tumor necrosis factor; Tumor Necrosis Factor-alpha - genetics; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-TNF; Denmark; Spain; cognition; sickness behavior; inflammation; Barnes maze; aging; TNF; LPS