Randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of a single oral dose of vanoxerine for the conversion of subjects with recent onset atrial fibrillation or flutter to normal sinus rhythm: RESTORE SR - Piccini, Jonathan P.; Pritchett, Edward L.C.; Davison, Beth A.; Cotter, Gad; Wiener, Laura E.; Koch, Gary; Feld, Gregory; Waldo, Albert; van Gelder, Isabelle C.; Camm, A. John; Kowey, Peter R.; Iwashita, Julie; et al. (Heart rhythm, 2016)
Keywords: Administration, Oral; Aged; Anti-Arrhythmia Agents - administration & dosage; Anti-Arrhythmia Agents - adverse effects; Antiarrhythmic; Atrial fibrillation; Atrial Fibrillation - drug therapy; Atrial Flutter - drug therapy; Cardioversion; Clinical trial; Double-Blind Method; Female; Heart Rate - drug effects; Humans; Male; Middle Aged; Piperazines - administration & dosage; Piperazines - adverse effects; Prospective Studies; Tachycardia, Ventricular - chemically induced; Treatment Outcome; Vanoxerine; Antiarrhythmic; Cardioversion; Clinical trial; Atrial fibrillation; Vanoxerine