Exploring vortioxetine combination with intranasal esketamine: A feasible alternative to SSRI/SNRI? - Insights from the REAL-ESK study - d’Andrea, Giacomo; Miuli, Andrea; Pettorruso, Mauro; Cavallotto, Clara; Marrangone, Carlotta; Cocco, Alessio; De Filippis, Sergio; Martiadis, Vassillis; Andriola, Ileana; Barlati, Stefano; Vita, Antonio; Dell'Osso, Bernardo Maria; et al. (Journal of affective disorders, 2024)
Keywords: Administration, Intranasal; Adult; Antidepressive Agents - administration & dosage; Antidepressive Agents - therapeutic use; Depression; Depressive Disorder, Major - drug therapy; Depressive Disorder, Treatment-Resistant - drug therapy; Drug Therapy, Combination; Emotional blunting; ESK-NS; Female; Glutamate; Humans; Ketamine - administration & dosage; Ketamine - adverse effects; Male; Middle Aged; Psychiatric Status Rating Scales; Psychiatric/Mental Health; Selective Serotonin Reuptake Inhibitors - administration & dosage; Serotonin and Noradrenaline Reuptake Inhibitors - administration & dosage; Serotonin and Noradrenaline Reuptake Inhibitors - pharmacology; TRD; Treatment Outcome; Vortioxetine; Vortioxetine - administration & dosage; Depression; Glutamate; Emotional blunting; Vortioxetine; ESK-NS; TRD