Normal Thymic Architecture and Negative Selection Are Associated with Aire Expression, the Gene Defective in the Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED) - Zuklys, Saulius; Balciunaite, Gina; Agarwal, Anni; Fasler-Kan, Elizaveta; Palmer, Ed; Hollander, Georg A (The Journal of immunology (1950), 2000)
Keywords: AIRE gene; AIRE Protein; Animals; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy; Cell Communication - genetics; Cell Communication - immunology; Cell Differentiation - genetics; Cell Differentiation - immunology; Embryonic and Fetal Development - genetics; Embryonic and Fetal Development - immunology; Epithelial Cells - cytology; Epithelial Cells - immunology; Epithelial Cells - metabolism; Gene Expression Regulation - immunology; Immune Tolerance - genetics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Polyendocrinopathies, Autoimmune - genetics; Polyendocrinopathies, Autoimmune - immunology; Polyendocrinopathies, Autoimmune - pathology; Proto-Oncogene Proteins - biosynthesis; Proto-Oncogene Proteins - physiology; RNA, Messenger - biosynthesis; Stromal Cells - cytology; Stromal Cells - immunology; Stromal Cells - metabolism; Thymus Gland - anatomy & histology; Thymus Gland - cytology; Thymus Gland - growth & development; Thymus Gland - immunology; Transcription Factor RelB; Transcription Factors - biosynthesis; Transcription Factors - deficiency; Transcription Factors - genetics; Transcription Factors - physiology; Transcription, Genetic - immunology